Scanning electron micrographs illustrate face and brain defects in GD 10 embryos following GD 8 maternal ethanol treatment. Comparison to a control embryo (A, B) illustrates abnormal upper midface and forebrain contours in the 2 affected embryos shown (C–F). In both affected embryos the medial nasal prominences (M) are abnormally positioned, being directed away from the lateral nasal prominences (L) and allowing full view of the developing vomeronasal organs (arrow). As compared with control, the interior of the forebrain in each of the affected embryos appears hypoplastic, with the degree of affect being consistent with that for the face. C = corpus striatum, curved arrow = optic stalk. Bars = 100 lm (modified from Sulik et al., 1986).