Author affiliations: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington (Ross L. Prentice, Marian L. Neuhouser, Ruth E. Patterson, Lesley F. Tinker); Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland (Pamela A. Shaw); Medical Research Council Dunn Human Nutrition Unit, University of Cambridge, Cambridge, United Kingdom (Sheila A. Bingham); Department of Epidemiology, University of Washington, Seattle, Washington (Shirley A. A. Beresford); Kaiser Permanente Division of Research, Oakland, California (Bette Caan); Stanford Prevention Research Center, Palo Alto, California (Marcia L. Stefanick); University of Tennessee Health Sciences Center, Memphis, Tennessee (Suzanne Satterfield); Department of Nutritional Sciences, University of Arizona, Tucson, Arizona (Cynthia A. Thomson); Department of Community and Behavioral Health, University of Iowa, Iowa City, Iowa (Linda Snetselaar); Medstar Research Institute, Washington, District of Columbia (Asha Thomas); and Johns Hopkins University/Sinai Hospital, Baltimore, Maryland (Asha Thomas).
This work was supported by the National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services (contracts N01WH22110, 24152, 32100-2, 32105-6, 32108-9, 32111-13, 32115, 32118-19, 32122, 42107-26, 42129-32, and 44221). Clinical Trials Registration: ClinicalTrials.gov identifier: NCT00000611. Dr. Prentice's work was partially supported by grant CA53996 from the National Cancer Institute.
The authors thank the WHI investigators and staff for their outstanding dedication and commitment. A full listing of WHI investigators can be found at the following website: http://www.whi.org
A list of key WHI investigators involved in this research follows. Program Office—National Heart, Lung, and Blood Institute, Bethesda, Maryland: Elizabeth Nabel, Jacques Rossouw, Shari Ludlam, Linda Pottern, Joan McGowan, Leslie Ford, Nancy Geller. Clinical Coordinating Centers—Fred Hutchinson Cancer Research Center, Seattle, Washington: Ross Prentice, Garnet Anderson, Andrea LaCroix, Charles L. Kooperberg, Ruth E. Patterson, Anne McTiernan; Wake Forest University School of Medicine, Winston-Salem, North Carolina: Sally Shumaker; Medical Research Labs, Highland Heights, Kentucky: Evan Stein; University of California at San Francisco, San Francisco, California: Steven Cummings. Clinical Centers—Albert Einstein College of Medicine, Bronx, New York: Sylvia Wassertheil-Smoller; Baylor College of Medicine, Houston, Texas: Aleksandar Rajkovic; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts: JoAnn Manson; Brown University, Providence, Rhode Island: Annlouise R. Assaf; Emory University, Atlanta, Georgia: Lawrence Phillips; Fred Hutchinson Cancer Research Center, Seattle, Washington: Shirley Beresford; George Washington University Medical Center, Washington, District of Columbia: Judith Hsia; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California: Rowan Chlebowski; Kaiser Permanente Center for Health Research, Portland, Oregon: Evelyn Whitlock; Kaiser Permanente Division of Research, Oakland, California: Bette Caan; Medical College of Wisconsin, Milwaukee, Wisconsin: Jane Morley Kotchen; MedStar Research Institute/Howard University, Washington, District of Columbia: Barbara V. Howard; Northwestern University, Chicago/Evanston, Illinois: Linda Van Horn; Rush Medical Center, Chicago, Illinois: Henry Black; Stanford Prevention Research Center, Stanford, California: Marcia L. Stefanick; State University of New York at Stony Brook, Stony Brook, New York: Dorothy Lane; The Ohio State University, Columbus, Ohio: Rebecca Jackson; University of Alabama at Birmingham, Birmingham, Alabama: Cora E. Lewis; University of Arizona, Tucson/Phoenix, Arizona: Tamsen Bassford; University at Buffalo, Buffalo, New York: Jean Wactawski-Wende; University of California at Davis, Sacramento, California: John Robbins; University of California at Irvine, Irvine, California: F. Allan Hubbell; University of California at Los Angeles, Los Angeles, California: Lauren Nathan; University of California at San Diego, LaJolla/Chula Vista, California: Robert D. Langer; University of Cincinnati, Cincinnati, Ohio: Margery Gass; University of Florida, Gainesville/Jacksonville, Florida: Marian Limacher; University of Hawaii, Honolulu, Hawaii: David Curb; University of Iowa, Iowa City/Davenport, Iowa: Robert Wallace; University of Massachusetts/Fallon Clinic, Worcester, Massachusetts: Judith Ockene; University of Medicine and Dentistry of New Jersey, Newark, New Jersey: Norman Lasser; University of Miami, Miami, Florida: Mary Jo O'Sullivan; University of Minnesota, Minneapolis, Minnesota: Karen Margolis; University of Nevada, Reno, Nevada: Robert Brunner; University of North Carolina, Chapel Hill, North Carolina: Gerardo Heiss; University of Pittsburgh, Pittsburgh, Pennsylvania: Lewis Kuller; University of Tennessee, Memphis, Tennessee: Karen C. Johnson; University of Texas Health Science Center, San Antonio, Texas: Robert Brzyski; University of Wisconsin, Madison, Wisconsin: Gloria E. Sarto; Wake Forest University School of Medicine, Winston-Salem, North Carolina: Mara Vitolins; and Wayne State University School of Medicine/Hutzel Hospital, Detroit, Michigan: Susan Hendrix.
Decisions concerning study design, data collection and analysis, interpretation of results, preparation of the manuscript, or submission of the manuscript for publication resided with committees comprising WHI investigators that included National Heart, Lung, and Blood Institute representatives.
Conflict of interest: none declared.