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Doctor consultations for common childhood problems in early and late childhood according to maternal prenatal anxiety symptom scores
OR (95% CI) for wheezing
OR (95% CI) for earache
OR (95% CI) for accident
N (%)CrudeAdjusted for sexN (%)CrudeAdjusted for sexN (%)CrudeAdjusted for sex
Maternal anxiety at 18 wkSymptoms between 6 and 18 mo
1st quartile (0-2)758/912 (83.1)1.0 (reference)1.0 (ref)924/988 (93.5)1.0 (reference)1.0 (reference)356/567 (62.8)1.0 (reference)1.0 (reference)
2nd quartile (3-4)611/732 (83.5)1.03 (0.79-1.33)1.03 (0.79-1.34)733/807 (90.8)0.69 (0.48-0.97)0.69 (0.48-0.97)294/456 (64.5)1.08 (0.83-1.39)1.08 (0.83-1.40)
3rd quartile (5-7)770/914 (84.2)1.09 (0.85-1.39)1.09 (0.85-1.40)903/978 (92.3)0.83 (0.59-1.18)0.83 (0.59-1.18)386/584 (66.1)1.16 (0.91-1.47)1.16 (0.91-1.47)
4th quartile (8-16)735/848 (86.7)1.32 (1.02-1.72)1.33 (1.02-1.73)773/868 (89.1)0.56 (0.40-0.78)0.56 (0.40-0.78)354/490 (72.2)1.54 (1.19-2.0)1.55 (1.19-2.01)
P trend.04.04.004.004.002.001
Maternal anxiety at 18 wkSymptoms between 69 and 81 mo
1st quartile (0-2)243/351 (69.2)1.0 (reference)1.0 (reference)739/1016 (72.7)1.0 (reference)1.0 (reference)318/444 (71.6)1.0 (reference)1.0 (reference)
2nd quartile (3-4)205/314 (65.3)0.84 (0.60-1.16)0.83 (0.60-1.15)567/777 (73.0)1.01 (0.82-1.25)1.01 (0.82-1.25)208/317 (65.6)0.76 (0.55-1.03)0.75 (0.55-1.03)
3rd quartile (5-7)246/383 (64.2)0.80 (0.59-1.09)0.78 (0.57-1.07)696/950 (73.3)1.03 (0.84-1.25)1.03 (0.82-1.25)271/416 (65.1)0.74 (0.55-0.99)0.74 (0.55-0.99)
4th quartile (8-16)213/310 (68.7)0.98 (0.70-1.36)0.97 (0.70-1.35)527/689 (76.5)1.22 (0.97-1.53)1.22 (0.97-1.53)196/313 (62.6)0.66 (0.49-0.90)0.66 (0.49-0.90)
P trend.74.69.12.12.009.009
Maternal anxiety at 32 wkSymptoms between 6 and 18 mo
1st quartile (0-2)658/793 (83.0)1.0 (reference)1.0 (reference)858/927 (92.6)1.0 (reference)1.0 (reference)325/526 (61.8)1.0 (reference)1.0 (reference)
2nd quartile (3-4)624/749 (83.3)1.02 (0.78-1.34)1.03 (0.79-1.34)762/836 (91.1)0.83 (0.59-1.17)0.83 (0.59-1.16)333/497 (67.0)1.26 (0.97-1.62)1.26 (0.97-1.62)
3rd quartile (5-7)812/971 (83.6)1.05 (0.81-1.35)1.05 (0.82-1.36)931/1021 91.2)0.83 (0.60-1.15)0.83 (0.60-1.15)376/579 (64.9)1.15 (0.90-1.46)1.15 (0.90-1.46)
4th quartile (8-16)813/954 (85.2)1.18 (0.91-1.53)1.19 (0.92-1.54)864/960 (90)0.72 (0.52-1.0)0.72 (0.52-1.0)394/556 (70.8)1.50 (1.17-1.94)1.50 (1.17-1.94)
P trend.20.19.06.06.006.006
Maternal anxiety at 32 wkSymptoms between 69 and 81 mo
1st quartile (0-2)213/313 (68.1)1.0 (reference)1.0 (reference)681/939 (72.5)1.0 (reference)1.0 (reference)286/405 (70.6)1.0 (reference)1.0 (reference)
2nd quartile (3-4)209/322 (64.9)0.87 (0.62-1.21)0.86 (0.61-1.19)607/824 (73.7)1.06 (0.86-1.31)1.06 (0.86-1.31)247/366 (67.5)0.86 (0.64-1.17)0.86 (0.63-1.17)
3rd quartile (5-7)260/400 (65.0)0.87 (0.64-1.19)0.85 (0.62-1.16)727/993 (73.2)1.04 (0.85-1.27)1.04 (0.85-1.27)275/409 (67.2)0.85 (0.63-1.15)0.85 (0.63-1.15)
4th quartile (8-16)249/351 (70.9)1.15 (0.82-1.60)1.13 (0.81-1.58)583/762 (76.5)1.23 (0.99-1.54)1.23 (0.99-1.54)212/355 (59.7)0.62 (0.46-0.83)0.62 (0.46-0.83)
P trend.43.48.10.10.003.003