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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
Cancer Res. Author manuscript; available in PMC 2010 August 1.
Published in final edited form as:
Cancer Res. 2009 August 1; 69(15): 6021–6026.
Published online 2009 July 21. doi: 10.1158/0008-5472.CAN-09-1086

Figure 3

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Physiological angiogenesis is unaltered in TEM8−/− mice. Vessel structure at P10.5 in the developing retina (A), the rate of wound closure (B), the number of vessels in wounds (C) and vessel structure in the uterus (D) appeared similar between knockout and wildtype mice. D, In the knockouts a decreased nuclear density (DAPI, blue) corresponding to areas with excessive ECM deposits (see Fig. 2) was frequently observed. CD31-positive vessels (green); NG2-positive pericytes (red). Bar, 20µm.

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