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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
Cancer Lett. Author manuscript; available in PMC 2010 October 8.
Published in final edited form as:
Cancer Lett. 2009 October 8; 283(2): 152–158.
Published online 2009 April 17. doi: 10.1016/j.canlet.2009.03.033

Figure 2

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Inhibition of DOX and DNP-SG transport in RLIP76-proteoliposomes by cdc2

14C-DOX (panels A and B) and 3H-DNPSG (panels C and D) transport activity was measured as ATP-dependent DOX and DNP-SG uptake in artificial liposomes reconstituted with purified rec-RLIP76. Control included liposomes prepared without RLIP76. Purified cdc2 protein was added in varying ratio to the transport reaction mixture. Results presented are representative from three separate experiments, each with triplicate determinations. •, control-liposomes treatment; ■, cdc2-proteoliposomes treatment; * p < 0.005 compared with control-liposomes treatment

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