Search tips
Search criteria 


Logo of jcmPermissionsJournals.ASM.orgJournalJCM ArticleJournal InfoAuthorsReviewers
J Clin Microbiol. Nov 1986; 24(5): 894–898.
PMCID: PMC269059
Effect of age and preexisting antibody on serum antibody response of infants and children to the F and G glycoproteins during respiratory syncytial virus infection.
B R Murphy, D W Alling, M H Snyder, E E Walsh, G A Prince, R M Chanock, V G Hemming, W J Rodriguez, H W Kim, B S Graham
, et al.
The serum antibody response of 50 infants and children infected with respiratory syncytial virus (RSV) was determined by a glycoprotein-specific enzyme-linked immunosorbent assay, and the effects of age and preexisting antibody titer at the time of RSV infection on response to the G and F glycoproteins of RSV were examined. The immune response to the G and F glycoproteins was assessed with anti-human immunoglobulin A to permit measurement of the response of young infants in the presence of maternally derived immunoglobulin G. The findings suggested that age primarily affects the response to the F glycoprotein and that preexisting antibody titer affects the response to the G glycoprotein.
Full text
Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (964K), or click on a page image below to browse page by page.
Articles from Journal of Clinical Microbiology are provided here courtesy of
American Society for Microbiology (ASM)