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From:
Published online Mar 5, 2009. doi: 10.1186/ar2636
Table 2
Relationship between adiposity measures and risk of primary joint replacement
VariableNumber of cases in each quartileHazard ratio95% confidence intervalP value
Weight (kg)
 Q1 (F <59.7, M <73.0)136 (9,756)1.00
 Q2 (F 59.7 to 66.2, M 73.0 to 79.7)202 (9,485)1.581.27 to 1.97
 Q3 (F 66.2 to 74.6, M 79.7 to 87.4)269 (9,418)2.171.77 to 2.67
 Q4 (F >74.6, M >87.4)401 (9,329)3.442.83 to 4.18
 Linear model (per 10 kg)1.421.36 to 1.48<0.001
Body mass index (kg/m2)
 Q1 (F <23.2, M <24.7)128 (9,663)1.00
 Q2 (F 23.2 to 25.9, M 24.7 to 26.8)211 (9,511)1.651.32 to 2.05
 Q3 (F 25.9 to 29.3, M 26.8 to 29.2)302 (9,458)2.482.01 to 3.05
 Q4 (F >29.3, M >29.2)367 (9,354)3.442.80 to 4.22
 Linear model (per 5 kg/m2)1.601.51 to 1.70<0.001
Waist circumference (cm)
 Q1 (F <71.0, M <87.0)136 (9,943)1.00
 Q2 (F 71.0 to 78.0, M 87.0 to 93.0)222 (9,612)1.591.29 to 1.97
 Q3 (F 78.0 to 87.0, M 93.0 to 99.0)290 (9,399)2.071.68 to 2.54
 Q4 (F >87.0, M >99.0)360 (9,025)2.772.26 to 3.39
 Linear model (per 10 cm)1.381.31 to 1.45<0.001
Waist-to-hip ratio
 Q1 (F < 0.74, M < 0.88)193 (9,553)1.00
 Q2 (F 0.74 to 0.78, M 0.88 to 0.92)234 (9,516)1.130.94 to 1.37
 Q3 (F 0.78 to 0.82, M 0.92 to 0.96)264 (9,498)1.231.02 to 1.48
 Q4 (F > 0.82, M > 0.96)317 (9,410)1.461.21 to 1.76
 Linear model (per 0.1 unit)1.231.12 to 1.35<0.001
Fat mass (kg)
 Q1 (F <21.1, M <18.4)125 (9,586)1.00
 Q2 (F 21.1 to 26.5, M 18.4 to 23.0)209 (9,502)1.711.37 to 2.13
 Q3 (F 26.5 to 32.9, M 23.0 to 27.9)273 (9,438)2.261.83 to 2.80
 Q4 (F >32.9, M >27.9)398 (9,312)3.512.87 to 4.30
 Linear model (per 10 kg)1.611.52 to 1.71<0.001
Percentage fat (%)
 Q1 (F <35.3, M <25.0)143 (9,568)1.00
 Q2 (F 35.3 to 40.1, M 25.0 to 28.9)205 (9,506)1.451.17 to 1.80
 Q3 (F 40.1 to 44.6, M 28.9 to 32.6)260 (9,451)1.861.51 to 2.28
 Q4 (F >44.6, M >32.6)397 (9,313)2.992.46 to 3.63
 Linear model (per 10%)2.011.81 to 2.22<0.001
All models using sex-specific quartiles of adiposity measures adjusted for age, gender, country of birth, and highest level of education. All models using continuous adiposity measures adjusted for age, country of birth, and highest level of education, stratifying by gender, representing an approximate change of one standard deviation for each of the adiposity measures. Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile; F, female; M, male.
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