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J Clin Microbiol. 1986 May; 23(5): 965–966.
PMCID: PMC268763

Leukocyte survival in cerebrospinal fluid.


Delays in the laboratory examination of cerebrospinal fluid are commonly encountered in clinical medicine. The present studies were designed to evaluate changes in cerebrospinal fluid leukocyte counts relative to time elapsed before analysis. Neutrophil counts decreased most rapidly, being 68 +/- 10% (standard error of the mean) and 50 +/- 12% of initial values at 1 and 2 h, respectively. Lymphocyte and monocyte numbers were not significantly altered until 3 h.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Criteria for diagnosis of Guillain-Barré syndrome. Ann Neurol. 1978 Jun;3(6):565–566. [PubMed]
  • Hooshmand H, Escobar MR, Kopf SW. Neurosyphilis. A study of 241 patients. JAMA. 1972 Feb;219(6):726–729. [PubMed]
  • Olson LC, Buescher EL, Artenstein MS, Parkman PD. Herpesvirus infections of the human central nervous system. N Engl J Med. 1967 Dec 14;277(24):1271–1277. [PubMed]
  • Pantazis CG, Kniker WT. Assessment of blood leukocyte microbial killing by using a new fluorochrome microassay. J Reticuloendothel Soc. 1979 Aug;26(2):155–170. [PubMed]

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