Genome-scale representation of TBP and SNAP50 binding relative to H3 acetylation. A. Each cell of the heatmap in the left panel represents a probe from the microarray, with each row of cells representing an 8 kb region of the genome centered on a peak of H3 acetylation aligned according to direction of transcription (indicated by the black arrow at top). The color of each cell is determined by the intensity of TBP-binding (green), SNAP50-binding (red), and histone H3 acetylation (grey). The top three panels to the right indicate the aggregate signal for each heatmap column for acetyl-H3 (top), TBP (middle) and SNAP50 (bottom). B. The top panel shows (black) acetylation peaks, and the bottom panel shows the average (over all regions examined) maximum G or C tract length in a 20 bp window around each position.
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