Search tips
Search criteria 


Logo of jcmPermissionsJournals.ASM.orgJournalJCM ArticleJournal InfoAuthorsReviewers
J Clin Microbiol. 1987 April; 25(4): 748–750.
PMCID: PMC266077

Differential immunoglobulin G subclass antibody titers to respiratory syncytial virus F and G glycoproteins in adults.


Two respiratory syncytial virus glycoproteins, F and G, which differ substantially in the amount of glycosylation were used as antigens in an enzyme-linked immunosorbent assay to determine immunoglobulin G (IgG) subclass titers in 30 experimentally infected healthy adults. The titers of antibodies to the F glycoprotein achieved in postinfection sera were highest in the IgG1 subclass, whereas those to the G glycoprotein were highest and comparable in the IgG1 and IgG2 subclasses. The high IgG2 response to the G glycoprotein suggests that it is seen by the immune system as a polysaccharide antigen, a hypothesis consistent with its large carbohydrate content.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (501K), or click on a page image below to browse page by page.

Articles from Journal of Clinical Microbiology are provided here courtesy of American Society for Microbiology (ASM)