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From:
Published online Feb 24, 2009. doi: 10.1186/1471-2164-10-90
Table 4
Top high-level functions identified by Ingenuity global function analysis of regulated genes in IL-6-versus NGF- stimulated PC 12 cells
Biological function classificationNumber of genesSignificance (p-value)
IL-6-regulated genes
Cancer612.98 × 10-6 to 5.16 × 10-3
Cellular Growth and Proliferation541.14 × 10-6 to 5.16 × 10-3
Cell Death474.54 × 10-6 to 5.16 × 10-3
Cell-to-Cell Signalling and Interaction462.26 × 10-7 to 5.16 × 10-3
Tissue Development452.26 × 10-7 to 5.15 × 10-3
Cellular Movement399.19 × 10-6 to 5.16 × 10-3
Cellular Development388.56 × 10-6 to 4.85 × 10-3
Small Molecule Biochemistry371.32 × 10-5 to 4.47 × 10-3
...
Nervous system development and function242.83 × 10-5 to 3.77 × 10-3
NGF-regulated genes
Cellular growth and proliferation377.86 × 10-5 to 8.88 × 10-3
Cell-to-cell signalling and interaction311.03 × 10-4 to 7.43 × 10-3
Molecular transport308.89 × 10-6 to 8.70 × 10-3
Cancer301.03 × 10-4 to 7.43 × 10-3
Cellular movement292.41 × 10-5 to 8.70 × 10-3
Cell death292.73 × 10-5 to 8.77 × 10-3
Neurological diseases291.07 × 10-4 to 8.70 × 10-3
Nervous system development and function291.60 × 10-4 to 8.70 × 10-3
p-values are from IPA Tool
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