A home-monitoring program can be an important part of the follow-up care after lung transplantation surgery. We report mortality data from the home-monitoring program at University of Minnesota. The data from 246 lung recipients who participated in the home-monitoring program from 1992 to 2002 were analyzed. Subjects’ first year adherence rates were correlated with survival using a Cox proportional hazards model. The analysis showed a hazard ratio of 0.744, (95% CI 0.338–1.635). Kaplan-Meier survival analysis comparing the high adherence group (adherence rate > 75%) and the lower adherence group (adherence rate <= 75%) showed a tendency toward better survival, but again, it did not reach statistical significance (p=0.24). Competing risks analysis for causes of death showed a decreased risk ratio of 0.416 (95% CI 0.123–1.407) among pulmonary related mortality.