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J Med Internet Res. 2008 Oct-Dec; 10(4): e27.
Published online 2008 September 8. doi:  10.2196/jmir.1080
PMCID: PMC2629369

The ALFA (Activity Log Files Aggregation) Toolkit: A Method for Precise Observation of the Consultation

Monitoring Editor: Gunther Eysenbach
Reviewed by Ashly Black, Alec Holt, and Elizabeth Borycki

Abstract

Background

There is a lack of tools to evaluate and compare Electronic patient record (EPR) systems to inform a rational choice or development agenda.

Objective

To develop a tool kit to measure the impact of different EPR system features on the consultation.

Methods

We first developed a specification to overcome the limitations of existing methods. We divided this into work packages: (1) developing a method to display multichannel video of the consultation; (2) code and measure activities, including computer use and verbal interactions; (3) automate the capture of nonverbal interactions; (4) aggregate multiple observations into a single navigable output; and (5) produce an output interpretable by software developers. We piloted this method by filming live consultations (n = 22) by 4 general practitioners (GPs) using different EPR systems. We compared the time taken and variations during coded data entry, prescribing, and blood pressure (BP) recording. We used nonparametric tests to make statistical comparisons. We contrasted methods of BP recording using Unified Modeling Language (UML) sequence diagrams.

Results

We found that 4 channels of video were optimal. We identified an existing application for manual coding of video output. We developed in-house tools for capturing use of keyboard and mouse and to time stamp speech. The transcript is then typed within this time stamp. Although we managed to capture body language using pattern recognition software, we were unable to use this data quantitatively. We loaded these observational outputs into our aggregation tool, which allows simultaneous navigation and viewing of multiple files. This also creates a single exportable file in XML format, which we used to develop UML sequence diagrams. In our pilot, the GP using the EMIS LV (Egton Medical Information Systems Limited, Leeds, UK) system took the longest time to code data (mean 11.5 s, 95% CI 8.7-14.2). Nonparametric comparison of EMIS LV with the other systems showed a significant difference, with EMIS PCS (Egton Medical Information Systems Limited, Leeds, UK) (P = .007), iSoft Synergy (iSOFT, Banbury, UK) (P = .014), and INPS Vision (INPS, London, UK) (P = .006) facilitating faster coding. In contrast, prescribing was fastest with EMIS LV (mean 23.7 s, 95% CI 20.5-26.8), but nonparametric comparison showed no statistically significant difference. UML sequence diagrams showed that the simplest BP recording interface was not the easiest to use, as users spent longer navigating or looking up previous blood pressures separately. Complex interfaces with free-text boxes left clinicians unsure of what to add.

Conclusions

The ALFA method allows the precise observation of the clinical consultation. It enables rigorous comparison of core elements of EPR systems. Pilot data suggests its capacity to demonstrate differences between systems. Its outputs could provide the evidence base for making more objective choices between systems.

Keywords: Video recordings, process assessment, observation, attitude to computer, professional-patient relations, general practice, family practice, decision modeling, process assessment, medical informatics, computers, medical records systems, computerized, electronic patient record (EPR), electronic medical record (EMR), evaluation methodologies, usability

Introduction

Electronic Patient Record (EPR) Systems Vary, and These Differences Provide Opportunities to Make Comparisons

Information and communications technology is ever more widely used in health care [1,2]; however, most EPR systems have grown organically, rather than being based on development specifications. Most countries have started with multiple small vendors developing EPR systems to meet the needs of the GP customers. Subsequently, commercial and regulatory pressures have reduced that number over time [3]; however, even within the same health system, the interfaces and functionalities clinicians use vary [4], as is the way they integrate the computer into the consultation [5]. Health systems are moving toward introducing new enterprise-wide information systems, which provide the opportunity for improved efficiency and patient safety through data sharing across the health system, so-called systemic interoperability [6]. The implementation of these new systems provides an opportunity to improve the interface and functionality, or, at the very least, have a rational reason for adopting the best design features of the existing systems.

Using Video to Record the Impact of the EPR on the Clinical Consultation

For nearly a decade, we have been developing a video-based method to measure the influence of technology on the clinical consultation. We started with a single channel video, but found that, without simultaneously displaying the clinical system screen and closely questioning the clinician about their objectives behind interactions, it was impossible to interpret the video [7]. Trying to measure the precise length of interactions was also challenging.

We recognized that analogue video (which did not have an accurate time stamp), and using a stopwatch to time events in the consultation, had major limitations. Our next development was to record 3 channels of video: (1) wide-angle view of the consultation, (2) view of clinician’s head and upper body, and (3) screen capture. We used professional video recording tools to do this, as we needed an accurate time stamp to synchronize the videos. Although we produced useful output, the expense and the setup meant that this was not going to be a readily deployable technique [8].

Therefore, we set out to develop a recording method that would enable precise and objective measurement of consultation activities. The system would have to meet the following objectives: (1) can be readily set up in real consulting rooms or clinics in less than an hour; (2) be reliable and could be readily set up by others in a range of settings; (3) provide objective time stamps of activities within the consultation, allowing the synchronization and subsequent simultaneous viewing of multiple measures; and (4) produce an output that could be used by computer software engineers to develop better systems.

Lack of Readily Available Applications to Compare EPR Applications

We initially reviewed existing applications that we could use to meet these specifications but found none. We looked at applications widely used for (1) qualitative research, (2) transcription and analysis of audio or video recordings, (3) usability testing, and (4) screen casting for demonstrations or training materials. Their shortcomings, compared with our requirements, are shown in Table 1.

Table 1
Existing applications investigated

There are well established applications used in qualitative research, such as ATLAS.ti (ATLAS.ti Scientific Software Development GmbH, Berlin, Germany) and QSR NVIVO (QSR International Pty Ltd, Melbourne, Australia) which allow detailed analysis and coding of text and multimedia data. They are not designed, however, to incorporate the precise monitoring of computer use that we require or to produce an output that can be exported into a package to develop UML diagrams. Transana (Wisconsin Center for Education Research, University of Wisconsin-Madison, Madison, WI, USA) provides facilities to perform a greater level of analysis by incorporating transcriptions; however its main analysis approach (which is based on the use of keyword, annotations, or their groupings) is not suitable to classify and measure doctor-computer interactions, which often include series of small durations or overlaps with patient interactions.

Widely used usability tools, such as Morae (TechSmith Corporation, Okemos, MI, USA), record observational data about computer use from multiple aspects. Due to the merged outputs they produce, they cannot be flexibly adopted according to research needs and are less helpful to obtain separate quantifiable measures for different combinations of interactions. Camtasia (TechSmith Corporation, Okemos, MI, USA), Adobe Captivate (Adobe Systems Incorporated, San Jose, CA, USA), and BB Flash Back (Blueberry Consultants Ltd, Birmingham, UK) are examples of screen-casting applications. While providing greater details about computer use, they are not optimized to classify interactions in a meaningful way. Focus of their outputs is too narrow to identify the effect of computer use on the overall consultation.

Rationale for This Development

In the absence of any suitable off-the-shelf application, we commenced our own development process to produce a set of applications that would enable researchers to capture the complexity of the computer-mediated consultation.

Methods

Developing a Specification

We developed a specification for our development program based on our objectives and on our experiential learning about the limitations of existing techniques. We recognized that our technique should be extendible, to combine a number of monitoring methods which, at that time, we would not be able to define. At the time, we identified: (1) an indeterminate number of video channels; (2) a transcript of the consultation, captured with a precise time stamp, possibly using voice recognition software; (3) output from pattern recognition software [9] and other change recognition technologies [10]; (4) aggregate log files from observation techniques that we could not anticipate, as elements of our specification.

Developing Separate Work Packages

We converted this work schedule into small work packages, which we developed separately on a largely opportunistic basis, as we had not received any consistent funding. The elements of this were:

1. To determine the optimal number of video channels and a low-cost way of recording. This should have time stamps to allow synchronization with other video channels and methods of data collection.

2. To find a reliable way to code the video footage, so we could navigate directly to particular activities in the consultation and measure their durations.

3. To automate the capture of body language and eye contact, using pattern recognition and gaze detection direction technologies.

4. To aggregate all these elements into a single navigable analysis output.

5. To introduce the ability to export data in a format that could readily be utilized by software engineers to improve systems.

Multichannel Video

We explored using 3, 4, and 5 channels of video, mixed onto a single screen, as well as a 4-channel version where clicking on a screen would enlarge that window to full screen (Figure 1). The additional channels experimented with since the 3-channel stage are the cameras focused on the patient’s upper body and the clinician’s facial view. We showed example consultations to experienced educationalists and academics accustomed to assessing video consultations, and we conducted semi-structured interviews to elicit their opinions [11].

Figure 1
The multichannel video output, combined recordings of clinical computer system screen and 3 views of consultation

We also needed to identify low-cost methods of filming the consultation, ideally using unobtrusive tools, which recorded sound and video with a digital time signal so that precise synchronization was possible [12].

Capturing and Coding Consultation Activity

We needed to be able to code interactions in the consultation so that we could readily navigate to a particular activity (eg, prescribing) and also identify its duration. We selected a flexible software called “ObsWin” (Antam Ltd, London, UK) to do this [13] (Figure 2). We conducted reliability tests of our manual coding method using multiple observers coding simulated blood pressure management follow-up consultations. We used intra-class correlation coefficient as an index of reliability [14]. Subsequently, we compared the manual coding time for prescribing activities with frame-by-frame analysis of the video to further assess the reliability of our approach.

Figure 2
Observational data capture using ObsWin, rating interface and outputs with summary statistics

Wherever possible, we set out to automate the time stamps for the start and end of activities in the consultation. We developed a User Action Recording (UAR) application to measure the precise time stamp of keyboard use (each key depression is recorded and time stamped), as well as all mouse clicks and coordinates. We also produced a Voice Activity Recorder (VAR), which detects and time stamps the start and end of speech (Figure 3).

Figure 3
Time-stamped consultation transcript creation using VAR

Automated Capture of Body Language

We automated the capture of body language to interpret nonverbal interactions and the direction of gaze to infer eye contact between clinician and patient. We experimented with Algol, an experimental pattern recognition software (PRS) not released as a commercial product (Main Highway Services, Winchester, UK), exploring correlation between movements detected with the software and manually detected activity [15] (Figure 4). We explored the possibility of obtaining software that measured the direction of gaze.

Figure 4
Measurement of nonverbal interactions using PRS, patient’s head nodding and doctor’s keyboard use

Aggregation and Navigation Application

We needed to aggregate the output from multiple data collection systems (Figure 5) into a single application that would be readily navigable. It needed to be able to flexibly load any number of input files and produce outputs that could be readily utilized in other applications. Unsuccessful effort to identify an appropriate proprietary application resulted in the in-house development of the Log Files Aggregation (LFA) application [16].

Figure 5
Time stamped log files created by three different consultation activity observation methods.

Output That Could Facilitate Better Clinical Computer System Development

We wanted to produce an output that would be readily interpretable by software engineers, so that our findings had a utility beyond the health care community. We specified our aggregation tool to export the combined log files in XML (extensible mark-up language) format, so they can be readily imported and interpreted by other applications. Process models of consultation tasks created using the UML, a standard modeling and specification notation widely used in software engineering, was chosen as our main mechanism for representing the use and impact of clinical system features within the consultation.

Pilot Recording of Consultations

We developed our method using simulated consultations between clinicians and actor patients within a simulated clinical environment. We initially developed the technique using standard consultations (eg, follow-up blood pressure checks [14]) and then a wider range of clinical problems.

We needed to know whether our technique was practical to set up within a standard consulting room and could cope with background noise, variable lighting including window position, and room size. We next tested our technique using actor patients in GP surgery premises. We found that audio recording from 1 camera was satisfactory; modern cameras coped well with variations in lighting, and 2 people could set up the cameras and install the other data-capture methods in less than 20 minutes. We found that the cameras and other data-capture tools could capture more than an hour’s data, but that it was prudent to remove screen capture and video data in a pause between consultations after 45 minutes.

We next developed a protocol that included our technical method, obtaining proper consent from patients and securing the data. We wanted to obtain pilot data from the 4 different most used brands of GP EPR systems, so we could make comparisons. These 4 brands are: (1) EMIS LV, the longest established and, at the time of the study, the most used system; (2) EMIS PCS, a more modern version from the same manufacturer; (3) INPS Vision; and (4) iSoft Synergy. EMIS LV is largely character user interface (CHUI) driven, whereas the other 3 have graphical user interfaces (GUI).

In our pilot analysis, we only included coding carried out using the picking list or other routine coding tools. We did not include data entry forms or templates that could facilitate more rapid data entry. The 4 GPs we filmed had used their current computer system for at least 3 years and had not routinely consulted with paper records for at least this period.

Statistical Methods

We planned to compare the time taken to carry out clinical coding, prescribing, and other routine tasks in the clinical consultation. We expected data from a small pilot to not have a normal distribution. This expectation is for 2 reasons: (1) we have a small sample and (2) we expected a skewed distribution because sometimes these tasks take a long time, but they always take a minimum time. We used box whisker plots to visually compare actions that were frequently recorded. We also used nonparametric tests (Mann-Whitney U test) to differentiate between EMIS LV (the then most used brand of GP EPR system) with the other systems. We next used the Krushkal-Wallis to explore any statistically significant difference in mean ranking. We used SPSS version 15 to carry out these analyses.

Ethical Considerations

We obtained ethical approval for the pilot recording of live consultations via the National Health Services Central Office for Research Ethics Committees (COREC). The protocol included making proper provision for the secure transport and storage of media and limiting access.

We used a 3-step process to obtain consent from patients to be video recorded. First, the video sessions were marked as such in participating practices, so that patients who booked into these sessions knew they were going to have their consultation video taped by 3 cameras as part of a research project. Second, they signed consent at the start of the consultation and were told that, if they did not want the video used after the consultation, they were free to say so. Finally, they and the clinician signed consent after the consultation stating that they remained willing for the consultation data to be used in research.

Results

Technical and Pilot Investigation Results

The results initially report a summary of our final technical method and then the results of our pilot study. The full description of the technical process is contained in Appendix 1.

Number of Video Channels Optimal for Analysis

We found 4 video channels to be optimal for observing the consultation. Our 3-channel video method, which provides an overview of the consultation, the clinician’s upper body, and screen capture, overcame most of the problems associated with single-channel observation [17]; however, a qualitative investigation suggested a fourth channel filming the head and upper torso of the patient was essential to capture the patient’s body language [11] (see Multimedia Appendix 3). In 2006, we found we could source the necessary hardware for 3-channel video around 1100 Euros [18] (or 1500 Euros for 4 channels).

Coding Consultation Activity

We used our in-house–developed UAR to capture mouse and key movement and VAR to time stamp the start and end of speech. We have piloted the use of UAR to compare the time taken to code a new problem and to issue a single acute prescription on 2 different GP computer systems [19].

The use of VAR overcame the limitations of manual coding of the start and end of speech. Prior to using VAR, we found that training manual raters could reliably code simulated consultations [14], but when presented with a heterogeneous mixture of real consultations, some activities were less reliably coded. The VAR also enables us to identify who initiates and terminates silence. We have observed how the clinician sometimes makes purposeless use of the IT to initiate silence to control the consultation [20].

Automated Capture of Body Language

We have extensively tested pattern recognition software to see if we can automate the capture of body language and movements such as affirmative head nodding; however, limitations in this technology, and our ability to process it, have left us unable to correlate this with the output from our manual observations.

The Log File Aggregation (LFA) Tool for Synchronizing and Simultaneous Viewing of Log Files

The LFA tool combines any number of time-stamped log files of different formats. The data imported into LFA can be viewed as histograms or occurrence graphs (Figure 6). The power of this tool in analysis is that clicking on a rectangle representing a specific variable takes the user directly to the appropriate spot in the multichannel video (see Multimedia Appendix 4). This enables users to navigate into any spot in the consultation they wish to study and simultaneously view all the log files relating to that point in time. Reader programs could successfully interpret XML output from the ALFA tool.

Figure 6
Analyzable outputs of the ALFA tool after aggregation

Output That Can Be Used by Software Developers

UML sequence diagrams demonstrated the clinicians’ use of EPR system components within the consultation. They contrasted the variations of computer use and how this might be related to interface features. Software developers could examine these process models to evaluate the use and performance of design characteristics within a consultation. We have used the UML outputs to contrast the definition of the presenting problem, prescribing [21], past encounter reviewing, and BP data entry stages (Figure 7) [22]. Examples for design features that we could identify as having an impact on the consultation are: (1) navigation method (use of icons, function, or arrow keys), (2) structure of the main interface (single, sub, or tab-separated windows, (3) display of alerts or prompts, (4) mechanism for searching coded data, (5) retrieving of historical data, etc. The output from LFA automatically creates the framework of a UML sequence diagram. It takes approximately an hour to manually annotate the remaining sequences in a 10-minute consultation.

Figure 7
Blood pressure data recording interfaces of 4 different EPR systems and sequence diagrams for the interactions observed

Pilot Data

There is considerable heterogeneity of computer use between consultations. We collected initial data from 22 consultations from 4 practices. Each computer system was only used by 1 GP. The GPs generally coded between 1 and 3 items per consultation, though 12 items were coded in one iSoft consultation, and the GP using EMIS LV appeared to code more. The summary of the coding carried out in each consultation is shown in Table 2. Only 2 of the 22 patients seen in this pilot asked to have the cameras switched off. No patients or clinicians withdrew consent for video material to be used post consultation.

Table 2
Coding carried out in the pilot consultations

We observed differences in time taken to code data, prescribe, and repeat prescribe into the computer systems, though we only had sufficient episodes of coding data and acute (new) prescribing to make any sort of statistical comparison. The descriptive findings are shown in Table 3, and the coding and repeat prescribing data are illustrated using box-whisker plots (Figure 8 and Figure 9.) The clinician using EMIS LV (the CHUI interface) appears to take longer to code items than users of other systems. Their mean ranking (Kruskal-Wallis test) was in the following order: EMIS LV, slowest (highest median); then iSoft Synergy was second slowest to code data; the fastest two were INPS Vision and EMIS PCS, having similar medians. The difference in medians was statistically significant (P = .007). Nonparametric (Mann-Whitney U) tests showed that they were all statistically significantly faster than EMIS LV; for EMIS PCS and INPS P < .01 and for iSoft Synergy P < .05 (Table 3).

Table 3
Comparison between EMIS LV (EL), EMIS PCS (EP), INPS Vision (IV), and iSoft Synergy (iS) of time taken to code data, prescribe, and record BP data
Figure 8
Box-whisker plot comparing coding times with different brands of GP EPR systems
Figure 9
Box-whisker plot comparing prescribing times with different brands of GP EPR systems

Acute prescribing appears to be faster with EMIS LV; however, although the EMIS LV prescriber was consistently at the faster end of prescribing time, there is overlap with the other systems shown in the box-whisker plots. Not surprisingly, the difference in medians was not statistically significantly different from the other two systems for which we have acute prescribing data (P = .71 and P = .64).

Discussion

Principal Findings

The ALFA toolkit allows greater precision of observation of the clinical consultation than other techniques. The current toolkit allows multiple video channels including screen capture, the consultation transcript, computer use, and speech to be precisely synchronized, timed, and navigated through. There is enough scope to add other input as required. Its output can be used to create models that software engineers could use to develop better EPR systems.

The multichannel filming appears to be acceptable to patients; however, the 4 practices involved were teaching and training practices where both medical students and trainee doctors regularly video tape themselves.

Our pilot data shows how the method allows small, but statistically significant, differences between clinical systems and users to be measured. Although these differences in time per coded item and prescription are relatively short, when multiplied up through a clinician’s day, better interfaces might result in a considerable time saving.

The UML models of BP recording show how having the previous reading readily available positively influences the clinical process and provide insights into how the new computer interfaces might be developed in the future. This principal could be carried forward into the recording of other common clinical information, for example, recording a smoking habit or adverse reactions to medication.

Implications

We developed this tool to meet our aspirations to evaluate the impact of technology on the consultation. Its precise time stamps could be used to compare clinical computer systems or to contrast the time taken with paper systems versus computerization. Comparative analysis of computer use and clinician-patient interactions could determine the common tasks and be used to develop theoretical models for computer-mediated consultation. We hope that our UML sequence diagrams will enable the clinical system designers to evaluate existing systems and also develop and evaluate new features.

The ALFA toolkit can also be used to measure the performance of the clinician or the reaction of the patient. Colleagues who have seen this technique have suggested that remedial doctors assessed in simulated surgeries could be given multichannel videos of their performance as a tool for reflection; if we could automate measures of body language, then this might be used as a formative assessment of communication skills.

The full set of tools created by the team and their source codes are freely available under a GNU General Public License (GNU GPL). Instructions for download, set up, sample files, and links to other related resources are made available as Web resources [23].

Limitations of the Method

Some of the parts of our development failed. We were unable to use the log file from the motion recognition software effectively. As yet, we have not been able to achieve a transcript from a voice-recognition system; these technologies still require training and are unable to recognize differing patients’ voices. We have not been able to access suitable methods to measure direction of gaze; commonly available tool kits are intrusive.

We have run this development as a series of small-scale components, rather than as a comprehensive program.

Our pilot data only used one clinician per system. More data are needed to discover if these differences were clinician-related or system-related.

Comparison With the Literature

We are unaware of any similar technique that provides such precision of observation (see Multimedia Appendix 2). Table 4 compares the features of ALFA against popular existing techniques. Although the study of human computer interaction (HCI) is a well developed discipline, it focuses on the interaction between 1 or more individuals and 1 or more computer systems [24]. In HCI, the user-computer interaction has primacy; we wanted instead to develop a toolkit to capture the complex social interaction of the consultation, within which the clinician-patient activity is pre-eminent. 

Table 4
Comparison of ALFA toolkit features with existing tools

Evaluation methods in software engineering combine multiple techniques for observation [25, 26]. The analyzable products of these are often a data file stream combining visual or audio representations of sequence of activities in sensory channels [27]. We are not aware, however, of any application that enables such a range of log files to be aggregated, synchronized, and, where needed, exported into other applications. Some keyboard listening or spyware applications could identify the sequence of keyboard activities. Voice spectrum analyzer applications that can present visual data about sound levels also exist. Unlike UAR and VAR applications, these are not capable of timing the computer use or verbal interactions in an analyzable format.

This method examines the impact of the computer on the consultation from a broad sociotechnical perspective, as advocated by Coiera [28], rather than from a purely technical perspective. Rigorous and broadly acceptable evaluation frameworks of IT in health care should be capable of identifying problems, suitable tools for evaluation, and methods for applying them sensibly [29]. It potentially helps fill some of the gaps in the methods for evaluation of health care systems [30].

Call for Further Research

More research is needed on how to automate data collection regarding the impact of technology on the consultation. Improved voice-recognition techniques would save the time spent in transcribing. As well as filling in the gaps about how to use pattern-recognition software and visual gaze estimation software to capture body language, we need to consider how we might embed logs into active clinical systems so that, for example, the change in length in consultation associated with a new release of software can be automatically measured and potentially investigated.

We also need to explore with a larger sample what are true differences between EPR systems and what is clinician variation. Recording several clinicians using 1 system should enable us to do this.

Conclusions

We set out to develop tools that would provide objective time stamps of activities within the consultation, allowing their simultaneous viewing and analyzing interactions in detail. The ALFA toolkit allows multiple observations of the consultation to be aggregated, simultaneously navigated, and output into other applications. The output from the ALFA tool should provide the evidence, based on which improved technology and models for the consultation can be developed.

Acknowledgments

The authors wish to thank the Foundation Doctors and students on placements who have worked on these developments over the last 5 years. Elske Ammenwerth is Bernhard Pflug’s academic supervisor. The authors also thank MainHighway for use of the Algol software and technical support.

Abbreviations

ALFA
activity log file aggregation
BP
blood pressure
CHUI
character user interface
COREC
Central Office for Research Ethics Committees
EPR
electronic patient record
GP
general practitioner
GUI
graphical user interface
GPL
general public license
HCI
human computer interaction
LFA
log files aggregation
ODC
observational data capture
PRS
pattern recognition software
UAR
user action recording
UML
unified modeling language
VAR
voice activity recording
XML
extensible markup language

Multimedia Appendix 1

Technical design of ALFA toolkit

Multimedia Appendix 2

Comparison of ALFA toolkit features with existing tools

Multimedia Appendix 3

Sample multichannel video file

Multimedia Appendix 4

Demonstration video of navigable occurrence graph created by LFA stage

Multimedia Appendix 5

Source code for LFA tool

Multimedia Appendix 6

Source code for UAR tool

Conflicts of Interest:

None declared.

Authors' Contributions

Contributed by

Simon de Lusignan and Pushpa Kumarapeli contributed equally to this work. Simon de Lusignan has set out a strategy for the development of better tools to study the impact of IT on the consultation with Tom Chan. Simon de Lusignan wrote this paper with comments from the other authors. Pushpa Kumarapeli has developed the UAR and VAR applications and specification for UML modeling; he has also been involved in developing the specification and design of the ALFA application. Bernhard Pflug developed the ALFA application. Simon de Lusignan, Beryl Jones, and Tom Chan are Pushpa Kumarapeli’s academic supervisory team for his PhD. Jeremy van Vlymen provided technical support and input throughout the project, supporting many critical technical developments. George K. Freeman is the chair of the SGUL Clinical Consultation Research Group and has contributed to these developments.

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