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Mondor's disease, better known as superficial thrombophlebitis of the breast, is an uncommon disorder. Trauma and surgical biopsies head the top of the list of known causes. Over the past 25 to 30 years, various authors have proposed some new etiologies; however, the clinical course of the disease remains unchanged. This article describes three patients who presented for office visits and were diagnosed as having Mondor's disease. Although Mondor's disease is not a precancerous lesion, patients with atypical clinical courses should undergo close follow-up.