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Neoplasia. Dec 2008; 10(12): 1314–1324.
PMCID: PMC2586682
Neoplasia: The Second Decade
Alnawaz Rehemtulla
University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA
Address all correspondence to: Alnawaz Rehemtulla, PhD, University of Michigan, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200. E-mail: alnawaz/at/umich.edu
Received October 27, 2008; Revised October 27, 2008; Accepted October 27, 2008.
This issue marks the end of the 10-year anniversary of Neoplasia where we have seen exciting growth in both number of submitted and published articles in Neoplasia. Neoplasia was first published in 1999. During the past 10 years, Neoplasia has dynamically adapted to the needs of the cancer research community as technologies have advanced. Neoplasia is currently providing access to articles through PubMed Central to continue to facilitate rapid broad-based dissemination of published findings to the scientific community through an Open Access model. This has in part helped Neoplasia to achieve an improved impact factor this past year, demonstrating that the manuscripts published by Neoplasia are of great interest to the overall cancer research community. This past year, Neoplasia received a record number of articles for review and has had a 21% increase in the number of published articles.
During the past 3 years (2006–2008), Neoplasia has shown strong growth as evidenced in the number of articles published. As shown in Figure 1, the percentage of articles published in Neoplasia increased by 6% in 2007 and further increased by an astounding 21% in 2008. Manuscripts published in these pages continue to be of the utmost high quality and cover a broad range of research topics and reviews from many different and exciting areas of cancer research. Shown in Table 1 are examples of articles previously published which have been sorted by general topic area for the 2006–2008 publication time frame. Whereas many articles could be classified in several of these categories, it is evident that Neoplasia provides its readership with a broad coverage of the many exciting discoveries during the past year.
Figure 1
Figure 1
A plot of the percent increase in the number of articles published in Neoplasia from 2006 to 2008. For each year, the bar graph indicates the percentage increase over the prior year. Note a major jump in the percentage of published articles occurred in (more ...)
Table 1
Table 1
Major Research Topics of Publications in Neoplasia from 2006 to 2008.
Neoplasia continues to differentiate itself from other journals in many areas. One key example is that Neoplasia provides immediate open access to all of its published articles at the time of publication through PubMed Central. This policy allows for all of the articles published by Neoplasia to be accessible immediately to the worldwide cancer research communities and to patients interested in keeping up-to-date with the latest developments, which may affect their treatment decisions. This feature also provides authors' research findings available to the largest possible readership ensuring that articles published in Neoplasia will have significant impact. One metric of the success of Open Access can be found in the Thomson Scientific Impact Factor, which, for Neoplasia, has increased from 4.9 in 2006 to 5.7 in 2007, revealing both the high quality and impact of articles published by Neoplasia and the increased impact in the cancer field as judged by the escalating number of citations by other scientists.
In conclusion, Neoplasia has successfully adapted to the needs of the cancer research community by implementing leading-edge technological changes including online peer review and electronic hosting of articles on PubMed Central, which now provides for instant and Open Access for all articles published within our pages.
1. Klein PJ, Schmidt CM, Wiesenauer CA, Choi JN, Gage EA, Yip-Schneider MT, Wiebke EA, Wang Y, Omer C, Sebolt-Leopold JS. The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer. Neoplasia. 2006;8:1–8. [PMC free article] [PubMed]
2. Andriani F, Perego P, Carenini N, Sozzi G, Roz L. Increased sensitivity to cisplatin in non-small lung cancer cell lines after FHIT gene transfer. Neoplasia. 2006;8:9–17. [PMC free article] [PubMed]
3. Kiewlich D, Zhang J, Gross C, Xia W, Larsen B, Cobb RR, Biroc S, Gu J, Sato T, Light DR, et al. Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth. Neoplasia. 2006;8:18–30. [PMC free article] [PubMed]
4. Watson GA, Queiroz de Oliveira PE, Stang MT, Armstrong MJ, Gooding WE, Kuan S, Yim JH, Hughes SJ. Ad-IRF-1 induces apoptosis in esophageal adenocarcinoma. Neoplasia. 2006;8:31–37. [PMC free article] [PubMed]
5. Chekerov R, Klaman I, Zafrakas M, Koensgen D, Mustea A, Petschke B, Lichtenegger W, Sehouli JJ, Dahl E. Altered expression pattern of topoisomerase IIα (TOP2A) in ovarian tumor epithelial and stromal cells after platinum-based chemotherapy. Neoplasia. 2006;8:38–45. [PMC free article] [PubMed]
6. Liu Y, Lan Q, Siegfried JM, Luketich JD, Keohavong P. Aberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients. Neoplasia. 2006;8:36–51. [PMC free article] [PubMed]
7. Yan Y, Wang Y, Tan Q, Hara Y, Yun T, Lubet R, You M. Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. Neoplasia. 2006;8:52–58. [PMC free article] [PubMed]
8. Bismar TA, Demichelis F, Riva A, Kim R, Varambally S, He L, Kutok J, Aster JC, Tang J, Kuefer R, et al. Defining aggressive prostate cancer using a 12 gene model. Neoplasia. 2006;8:59–68. [PMC free article] [PubMed]
9. Loberg RD, Day LL, Dunn R, Kalikin LM, Pienta KJ. Inhibition of decay accelerating factor (CD55) attenuates prostate cancer growth and survival in vivo. Neoplasia. 2006;8:69–78. [PMC free article] [PubMed]
10. Goon P, Lip G, Boos C, Stonelake P, Blann A. Circulating endothelial cells and endothelial progenitor cells in cancer. Neoplasia. 2006;8:79–88. [PMC free article] [PubMed]
11. Hofmann M, Guschel M, Bernd A, Bereiter-Hahn J, Kaufmann R, Tandi C, Wiig H, Kippenberger S. Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model. Neoplasia. 2006;8:89–95. [PMC free article] [PubMed]
12. Taraboletti G, D'Ascenzo S, Giusti I, Marchetti D, Borsotti P, Millimaggi D, Giavazzi R, Pavan A, Dolo V. Bioavailability of VEGF in tumor shed vesicles depends on vesicle burst induced by acidic pH. Neoplasia. 2006;8:96–103. [PMC free article] [PubMed]
13. Webster JD, Yuzbasiyan-Gurkan V, Kaneene JB, Miller R, Resau JH, Kiupel M. The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors. Neoplasia. 2006;8:104–111. [PMC free article] [PubMed]
14. Kelavkar UP, Hutzley J, Dhir R, Kim P, Allen KG, McHugh K. Prostate tumor growth and recurrence can be modulated by the omega (ω)-6:ω-3 ratio in diet: athymic mouse xenograft model simulating radical prostatectomy. Neoplasia. 2006;8:112–124. [PMC free article] [PubMed]
15. Liu Y, Zhang W, Niu T, Cheung LH, Munshi A, Meyn RE, Rosenblum MG. Targeted apoptosis activation with GrB/scFvMEL modulates melanoma growth, metastatic spread, chemosensitivity and radiosensitivity. Neoplasia. 2006;8:125–135. [PMC free article] [PubMed]
16. Tabori U, Vukovic B, Zielenska M, Hawkins C, Braude I, Rutka J, Bouffet E, Squire J, Malkin D. The role of telomere maintenance in the spontaneous growth arrest pediatric low grade gliomas. Neoplasia. 2006;8:136–142. [PMC free article] [PubMed]
17. Thews O, Gassner B, Kelleher DK, Schwerdt G, Gekle M. Impact of extracellular acidity on the activity of p-glycoprotein and the cytotoxicity of chemotherapeutic drugs. Neoplasia. 2006;8:143–152. [PMC free article] [PubMed]
18. Tomlins S, Mehra R, Rhodes DR, Shah RB, Rubin MA, Bruening EE, Makarov V, Chinnaiyan AM. Whole transcriptome amplification for gene expression profiling and development of molecular archives. Neoplasia. 2006;8:153–162. [PMC free article] [PubMed]
19. Wolter KG, Wang SJ, Henson BS, Wang S, Griffith KA, Kumar B, Chen J, Carey TE, Bradford CR, D'Silva NJ. (-)-Gossypol inhibits growth of human head and neck squamous cell carcinoma in vivo. Neoplasia. 2006;8:163–172. [PMC free article] [PubMed]
20. Lo AK, Lo K, Tsao S, Wong H, Hui J, To K, Hayward S, Chui Y, Lau Y, Takada K, et al. Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells. Neoplasia. 2006;8:173–180. [PMC free article] [PubMed]
21. Wu Z, Siadaty MS, Riddick G, Frierson HF, Jr, Lee JK, Golden W, Knuutila S, Hampton GM, El-Rifai W, Theodorescu D. A novel method for gene expression mapping of metastatic competence in human bladder cancer. Neoplasia. 2006;8:181–189. [PMC free article] [PubMed]
22. Ghebeh H, Mohammed S, Al-Omair A, Qattan A, Lehe C, Al-Qudaihi G, Elkum N, Alshabanah M, Bin Amer S, Tulbah A, et al. The B7-H1 (PD-L1) T lymphocytes inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high risk prognostic factors. Neoplasia. 2006;8:190–198. [PMC free article] [PubMed]
23. McPhail LD, McIntyre DJ, Ludwig C, Kestell P, Griffiths JR, Kelland LR, Robinson S. Rat tumor response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindole acetic acid levels, and tumor necrosis. Neoplasia. 2006;8:199–206. [PMC free article] [PubMed]
24. Gimi B, Mori N, Ackerstaff E, Frost EE, Bulte JW, Bhujwalla ZM. Noninvasive MR imaging of endothelial cell response to human breast cancer cells. Neoplasia. 2006;8:207–213. [PMC free article] [PubMed]
25. Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L. Nanoparticle imaging of integrins on tumor cells. Neoplasia. 2006;8:214–222. [PMC free article] [PubMed]
26. Gros F, Yasmine S, de Guibert S, Branger B, Bernard M, Fauchet R, Amiot L. Soluble HLA-G molecules are increased during acute leukaemia especially in subtypes affecting monocytic and lymphoid lineages. Neoplasia. 2006;8:223–230. [PMC free article] [PubMed]
27. Oba Shinjo SM, Correa M, Ricca TI, Molognoni F, Pinhal MA, Neves IA, Marie SK, Sampaio LO, Nader HB, Chammas R, et al. Melanocyte transformation associated with substrate adhesion impediment. Neoplasia. 2006;8:231–242. [PMC free article] [PubMed]
28. Leung Y, Gao Y, Lau K, Zhang X, Ho S. ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated via estrogen receptor-β/NFκB crosstalk. Neoplasia. 2006;8:242–249. [PMC free article] [PubMed]
29. Duriseti KS, Winnard PT, Jr, Mironchik Y, Vesuna F, Raman A, Raman V. HOXA5 regulates hMLH1 expression in breast cancer cells. Neoplasia. 2006;8:250–258. [PMC free article] [PubMed]
30. Moffat BA, Chenevert TL, Meyer C, Mckeever PE, Hall DE, Hoff BA, Johnson TD, Rehemtulla A, Ross BD. The functional diffusion map: an imaging biomarker for early prediction of cancer treatment outcome. Neoplasia. 2006;8:259–267. [PMC free article] [PubMed]
31. Kwong J, Lee J, Wong K, Zhou X, Wong D, Lo K, Welch WR, Berkowitz RS, Mok SC. Candidate tumor suppressor gene DLEC1 is frequently down-regulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer. Neoplasia. 2006;8:268–278. [PMC free article] [PubMed]
32. Zeng G, Germinaro M, Micsenyi A, Monga NK, Bell A, Sood A, Malhotra V, Sood N, Midda V, Monga DK, et al. Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma. Neoplasia. 2006;8:279–289. [PMC free article] [PubMed]
33. Engl T, Relja B, Marian D, Blumenberg C, Mueller I, Beecken W, Jones J, Ringel EM, Bereiter-Hahn J, Jonas D, et al. CXCR4 chemokine receptor mediates prostate tumor cell adhesion via α5 and β3 integrins. Neoplasia. 2006;8:290–301. [PMC free article] [PubMed]
34. Trehin R, Figueiredo J, Pittet M, Weissleder R, Josephson L, Mahmood U. luorescent nanoparticle uptake for brain tumor visualization. Neoplasia. 2006;8:302–311. [PMC free article] [PubMed]
35. Taras D, Blanc J, Rullier A, Dugot-Senant N, Laurendeau I, Bièche I, Pines M, Rosenbaum J. Halofuginone suppresses lung metastasis of chemically-induced hepatocellular carcinoma in rats via MMP inhibition. Neoplasia. 2006;8:312–318. [PMC free article] [PubMed]
36. Kuefer R, Day KC, Kleer CG, Sabel MS, Hofer MD, Varambally S, Zorn CS, Chinnaiyan AM, Rubin MA, Day ML. The ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease. Neoplasia. 2006;8:319–329. [PMC free article] [PubMed]
37. Goldstein M, Meller I, Issakov J, Orr-Urtreger A. Novel genes implicated in embryonal, alveolar and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors. Neoplasia. 2006;8:332–343. [PMC free article] [PubMed]
38. Tsarfaty G, Stein GY, Moshitch-Moshkovit S, Kaufman DW, Cao B, Resau JH, Vande Woude GF, Tsarfaty I. HGF/SF increases tumor blood volume: a novel tool for in vivo functional molecular imaging of Met. Neoplasia. 2006;8:344–352. [PMC free article] [PubMed]
39. Moshitch-Moshkovitz S, Tsarfaty G, Kaufman DW, Stein GY, Shichrur K, Resau JH, Vande Woude G, Tsarfaty I. In vivo direct molecular imaging of early tumorigensis and malignant progression induced by transgenic expression of GFP-Met. Neoplasia. 2006;8:353–391. [PMC free article] [PubMed]
40. Olsen MW, Ley CD, Junker N, Hansen AJ, Lund EL, Kristjansen PE. Angiopoietin-4 inhibits angiogenesis and reduces interstitial fluid pressure. Neoplasia. 2006;8:362–372. [PMC free article] [PubMed]
41. Pérez-Carreón JI, López-García C, Fattel-Fazenda S, Arce-Popoca E, Alemán-Lazarini L, Hernández-García S, Le Berre V, Sokol S, Francois J, Villa-Treviño S. Gene expression profile related to the progression of preneoplastic nodules toward hepatocellular carcinoma in rats. Neoplasia. 2006;8:373–383. [PMC free article] [PubMed]
42. Liu Y, Zhang W, Cheung LH, Wu Q, Li C, Van Pelt CS, Rosenblum MG. The antimelanoma immunocytokine scFvMEL/TNF shows reduced toxicity and potent antitumor activity against human tumor xenografts. Neoplasia. 2006;8:384–393. [PMC free article] [PubMed]
43. Wan X, Shen N, Mendoza A, Khanna C, Helman LJ. CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to targeting mTOR/Hif-1a/VEGF signaling. Neoplasia. 2006;8:394–402. [PMC free article] [PubMed]
44. Mijatovic T, Mathieu V, Gaussin J, De Nève N, Ribaucour F, Van Quaquebeke E, Dumont P, Darro F, Kiss R. Cardenolide-induced lysosomal membrane permeabilization contributes therapeutic benefits in experimental human non-small-cell-lung cancers. Neoplasia. 2006;8:403–412. [PMC free article] [PubMed]
45. Jin Y, Mertens F, Kullendoref CM, Panagopoulos I. Fusion of the tumor suppressor gene CHEK2 and the gene for the regulatory subunit B of protein phosphatase 2 (PPP2R2A) in a childhood teratoma. Neoplasia. 2006;8:413–418. [PMC free article] [PubMed]
46. Lee O, Fueyo J, Xu J, Yung W, Lemoine MG, Lang FF, Bekele B, Zhou X, Alonso MA, Aldape KD, et al. Sustained angiopoietin-2 expression disrupts vessel formation and inhibits glioma growth. Neoplasia. 2006;8:419–428. [PMC free article] [PubMed]
47. Furth EE, Gustafson KS, Dai C, Gibson SL, Menard-Katcher P, Chen T, Koh J, Enders GH. Induction of the tumor suppressor p16Ink4a within regenerating crypts in ulcerative colitis. Neoplasia. 2006;8:429–436. [PMC free article] [PubMed]
48. Schmidt CM, Crowell PL, Yip-Schneider M, Savage JJ, Hertzler DA, II, Cummings WO. Cyclooxygenase-2 expression throughout hamster and human pancreatic neoplasia. Neoplasia. 2006;8:437–445. [PMC free article] [PubMed]
49. Ziauddin M, Yeow W, Maxhimer JB, Baras A, Chua A, Reddy RM, Tsai W, Cole GW, Jr, Schrump DS, Nguyen DM. Valproic acid, an anti-epileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells via mitochondria-dependent caspase activation. Neoplasia. 2006;8:446–457. [PMC free article] [PubMed]
50. Ogino S, Brahmandam M, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype (CIMP) in colorectal cancer. Neoplasia. 2006;8:458–464. [PMC free article] [PubMed]
51. Yoshimoto M, Joshua A, Chilton-MacNeill S, Bayani J, Selvarajah S, Evans AJ, Zielenska M, Squire JA. Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates genomic microdeletion of chromosome 21 is associated with rearrangement. Neoplasia. 2006;8:465–469. [PMC free article] [PubMed]
52. Baker CH, Pino MS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors. Neoplasia. 2006;8:470–476. [PMC free article] [PubMed]
53. van Laarhoven HW, Gambarota G, Lok J, Lammens M, Kamm YL, Wagener T, Punt CJ, Van der Kogel AJ, Heerschap A. Carbogen breathing differentially enhances blood plasma volume and 5-fluorouracil uptake in two murine colon tumor models with a distinct vascular structure. Neoplasia. 2006;8:477–487. [PMC free article] [PubMed]
54. Corbin IR, Li H, Chen J, Lund-Katz S, Zhou R, Glickson JD, Zheng G. Low density lipoprotein nanoparticles as magnetic resonance imaging contrast agents. Neoplasia. 2006;8:488–498. [PMC free article] [PubMed]
55. Brehm R, Rüttinger C, Fischer P, Gashaw I, Winterhager E, Kliesch S, Bohle RM, Steger K, Bergmann M. Transition from pre-invasive carcinoma in situ to seminoma is accompanied with a reduction of connexin43-expression in Sertoli cells and germ cells. Neoplasia. 2006;8:499–509. [PMC free article] [PubMed]
56. Kelavkar UP, Parwani A, Shappell SB, Martin W. Conditional expression of human 15-lipoxygenase-1 in mouse prostate induces prostatic intraepithelial neoplasia: the FLiMP mouse model. Neoplasia. 2006;8:510–522. [PMC free article] [PubMed]
57. Garcia GE, Arevalo N, Bhaskaran S, Gupta A, Kyprianou N, Kumar A. Akt and CREB mediated prostate cancer cell proliferation inhibition by NexrutineR a Phellodendron amurense extract. Neoplasia. 2006;8:523–533. [PMC free article] [PubMed]
58. Seshadri M, Mazurchuk R, Spernyak JA, Bhattacharya A, Rustum YM, Bellnier DA. Activity of the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) against human head and neck carcinoma xenografts. Neoplasia. 2006;8:534–542. [PMC free article] [PubMed]
59. Weihua Z, Tsan R, Nam D, Lu W, Fidler IJ. Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to become melanotic by inhibition of AKT. Neoplasia. 2006;8:543–550. [PMC free article] [PubMed]
60. Hopkins-Donaldson S, Belyanskaya LL, Simões-Wüst A, Sigrist B, Kurtz S, Zangemeister-Wittke U, Stahel R. p53-Induced apoptosis occurs in the absence of p14ARF in malignant pleural mesothelioma. Neoplasia. 2006;8:551–559. [PMC free article] [PubMed]
61. Madhu B, Waterton JC, Griffiths JR, Ryan AJ, Robinson S. The response of RIF-1 fibrosarcomas to the vascular disrupting agent ZD6126 assessed by in vivo and ex vivo 1H magnetic resonance spectroscopy. Neoplasia. 2006;8:560–567. [PMC free article] [PubMed]
62. Li H, Goswami PC, Domann F. AP-2γ induces p21 expression, arrests cell cycle, and inhibits tumor growth of human carcinoma cells. Neoplasia. 2006;8:569–577. [PMC free article] [PubMed]
63. Loberg RD, Day LL, Harwood J, Ying C, St John LN, Giles R, Neeley CK, Pienta KJ. CCL2 (monocyte chemoattractant protein-1) is a potent regulator of prostate cancer cell migration and proliferation. Neoplasia. 2006;8:578–586. [PMC free article] [PubMed]
64. Thomas CD, Walczak C, Kaffy J, Pontikis R, Jouanneau J, Volk A. Early effects of combretastatin-A-4-P assessed by anatomical and carbogen-based functional magnetic resonance imaging on rat bladder tumors implanted in nude mice. Neoplasia. 2006;8:587–595. [PMC free article] [PubMed]
65. Reiland J, Kempf D, Roy M, Denkins Y, Marchetti D. FGF2 binding, signaling and angiogenesis are modulated by heparanase in metastatic melanoma cancer. Neoplasia. 2006;8:596–606. [PMC free article] [PubMed]
66. Hama Y, Urano Y, Koyama Y, Kamiya M, Bernardo M, Paik R, Krishna MC, Choyke PL, Kobayashi H. In vivo spectral fluorescence imaging of submillimeter peritoneal cancer implants using a lectin-targeted optical agent. Neoplasia. 2006;8:607–612. [PMC free article] [PubMed]
67. Schaefer K, Brachwitz K, Braun Y, Diallo RI, Wai DH, Zahn S, Schneider DT, Kuhnen C, Vollmann A, Brockhoff G, et al. Constitutive activation of neuregulin/ERBB3 signaling pathway in clear cell sarcoma of soft tissue. Neoplasia. 2006;8:613–622. [PMC free article] [PubMed]
68. Ohh M. Ubiquitin pathway in VHL cancer syndrome. Neoplasia. 2006;8:623–629. [PMC free article] [PubMed]
69. Dai M, Jin Y, Gallegos JR, Lu H. Balance of yin and yang: ubiquitylation-mediated regulation of p53 and c-Myc. Neoplasia. 2006;8:630–644. [PMC free article] [PubMed]
70. Sun Y. E3 ubiquitin ligases as cancer targets and bio-markers. Neoplasia. 2006;8:645–654. [PMC free article] [PubMed]
71. Watson IR, Irwin MS. Ubiquitin and ubiquitin-like modifications of the p53 family. Neoplasia. 2006;8:655–666. [PMC free article] [PubMed]
72. Cheng J, Lee P, Bawa T, Gong L, Yeh ET. Role of de-sumoylation in the development of prostate cancer. Neoplasia. 2006;8:667–676. [PMC free article] [PubMed]
73. Izzi L, Attisano L. Ubiquitin-dependent regulation of TGFβ signaling in cancer. Neoplasia. 2006;8:677–688. [PMC free article] [PubMed]
74. Burger A, Amemiya Y, Kitching R, Seth AK. Novel RING E3 ubiquitin ligases in breast cancer. Neoplasia. 2006;8:689–695. [PMC free article] [PubMed]
75. Cheung S, Liu C, Chow J, Lee Y, Ip Y, Ho J, Fan S. Preoperative plasma transcript AA454543 level is an independent prognostic factor for hepatocellular carcinoma after partial hepatectomy. Neoplasia. 2006;8:696–701. [PMC free article] [PubMed]
76. von Rahden B, Stein HJ, Puehringer-Oppermann F, Sarbia M. c-myc Amplification is frequent in esophageal adenocarcinoma and correlated with up-regulation of VEGF-A expression. Neoplasia. 2006;8:702–707. [PMC free article] [PubMed]
77. Borowsky AD, Dingley KH, Ubick EA, Turteltaub KW, Cardiff RD, deVere White RW. Inflammation and atrophy precede prostate neoplasia in PhIP induced rat model. Neoplasia. 2006;8:708–715. [PMC free article] [PubMed]
78. Liu C, Chen Z, Chen Z, Zhang T, Lu Y. Multiple tumor types might originate from bone marrow-derived cells. Neoplasia. 2006;8:716–724. [PMC free article] [PubMed]
79. Akhavan A, McHugh KH, Guruli G, Bies RR, Zamboni WC, Strychor SA, Nelson JB, Pflug B. Endothelin receptor A blockade enhances taxane effects in prostate cancer. Neoplasia. 2006;8:725–732. [PMC free article] [PubMed]
80. Squarize CH, Castilho RM, Sriuranpong V, Pinto DS, Jr, Gutkind JS. A molecular cross-talk between the NFκB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia. 2006;8:733–746. [PMC free article] [PubMed]
81. Rebhun RB, Langley RR, Yokoi K, Fan D, Gershenwald JE, Fidler IJ. Targeting receptor tyrosine kinase on lymphatic endothelial cells for therapy of colon cancer lymph node metastasis. Neoplasia. 2006;8:747–757. [PMC free article] [PubMed]
82. Glunde K, Jie C, Bhujwalla ZM. Mechanisms of indomethacin-induced alterations in choline phospholipid metabolism of breast cancer cells. Neoplasia. 2006;8:758–771. [PMC free article] [PubMed]
83. Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher S. In vivo selection of phage for the optical imaging of human prostate carcinoma in mice. Neoplasia. 2006;8:772–780. [PMC free article] [PubMed]
84. Wang Q, Zhou Y, Evers B. Neurotensin phosphorylates GSK-3α/β through activation of PKC in human colon cancer cells. Neoplasia. 2006;8:781–787. [PMC free article] [PubMed]
85. Lammers T, Peschke P, Kühnlein R, Subr V, Ulbrich K, Huber P, Hennink W, Storm G. Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems. Neoplasia. 2006;8:788–795. [PMC free article] [PubMed]
86. Winnard PT, Jr, Kluth J, Raman V. Non-invasive optical tracking of red fluorescent protein expressing cancer cells in a model of metastatic breast cancer. Neoplasia. 2006;8:796–806. [PMC free article] [PubMed]
87. Blaheta R, Weich E, Marian D, Bereiter-Hahn J, Jones J, Jonas D, Michaelis M, Doerr HW, Cinatl J. Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix. Neoplasia. 2006;8:807–816. [PMC free article] [PubMed]
88. Ogata Y, Osaki T, Naka T, Iwahori K, Furukawa M, Nagatomo I, Kijima T, Kumagai T, Yoshida M, Tachibana I, et al. Overexpression of PIAS3 suppresses cell growth and restores drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivation. Neoplasia. 2006;8:817–825. [PMC free article] [PubMed]
89. Cerveira N, Ribeiro FR, Peixoto A, Costa V, Henrique R, Jeronimo C, Teixeira MR. TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions. Neoplasia. 2006;8:826–832. [PMC free article] [PubMed]
90. Morandi F, Chiesa S, Bocca P, Millo E, Salis A, Solari M, Pistoia V, Prigione I. Tumor mRNA transfected dendritic cells stimulate generation of CTL that recognize neuroblastoma associated antigens and kill tumor cells: immunotherapeutic implications. Neoplasia. 2006;8:833–842. [PMC free article] [PubMed]
91. Lee O, Hong S, Razvi MH, Dun Fa P, Powell SM, Smolkin M, Moskaluk CA, El-Rifai W. Expression of calcium binding proteins S100A2 and S100A4 in Barrett's adenocarcinomas. Neoplasia. 2006;8:843–850. [PMC free article] [PubMed]
92. Vignati S, Albertini V, Rinaldi A, Kwee I, Riva C, Oldrini R, Capella C, Bertoni F, Carbone GM, Catapano CV. Cellular and molecular consequences of peroxisome proliferator-activated receptor-γ activation in ovarian cancer cells. Neoplasia. 2006;8:851–861. [PMC free article] [PubMed]
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116. Shih A, Holland EC. Notch signaling enhances nestin expression in gliomas. Neoplasia. 2006;8:1072–1082. [PMC free article] [PubMed]
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135. Schmitz KJ, Lang H, Frey UH, Sotiropoulos GC, Wohlschlaeger J, Reis H, Takeda A, Siffert W, Schmid KW, Baba HA. The GNAS1 T393C polymorphism is associated with the clinical course in patients with intrahepatic cholangiocarcinoma. Neoplasia. 2007;9:159–165. [PMC free article] [PubMed]
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157. Veronique MM, Mathieu V, Mijatovic T, Gailly P, Debeir O, De Nève N, Van Damme M, Decaestecker C, Kondo Y, Kiss R, et al. 4-IBP: a σ1 receptor agonist decreases the migration of human cancer cells including glioblastoma cells in vitro and sensitizes them in vitro and in vivo to the cytotoxic insults of pro-apoptotic and pro-autophagic drugs. Neoplasia. 2007;9:358–369. [PMC free article] [PubMed]
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172. Subramanium C, Jarzembowski JA, Opipari AW, Jr, Castle VP, Kwok P. Creb-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor, trichostatin A. Neoplasia. 2007;9:495–503. [PMC free article] [PubMed]
173. Theodoro TR, Luango de Matos L, Sant Anna AV, Fonseca FL, Semedo P, Martins LC, Nader HB, Del Giglio A, Pinhal MS. Heparanase expression in circulating lymphocytes of breast cancer patients depends on the presence of the primary tumor and/or systemic metastasis. Neoplasia. 2007;9:504–510. [PMC free article] [PubMed]
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206. Li R, Boehm AL, Miranda MB, Shangary S, Grandis JR, Johnson DE. Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells. Neoplasia. 2007;9:801–811. [PMC free article] [PubMed]
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208. Puiffe M, Le Page C, Filali-Mouhim A, Ziertarska M, Ouellet V, Tonin PN, Chevrette M, Provencher DM, Mes-Masson A. Characterization of ovarian cancer ascites on cell invasion, proliferation, spheroid formation and gene expression in an in vitro model of epithelial ovarian cancer. Neoplasia. 2007;9:820–829. [PMC free article] [PubMed]
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212. Kollmar O, Rupertus K, Scheuer C, Junker B, Tilton B, Schilling MK, Menger MD. Stromal cell-derived factor (SDF)-1 promotes cell migration and tumor growth of colorectal metastasis. Neoplasia. 2007;9:862–870. [PMC free article] [PubMed]
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214. Sakariassen PØ, Immervoll H, Chekenya M. Cancer stem cells as mediators of treatment resistance in brain tumours: status and controversies. Neoplasia. 2007;9:882–892. [PMC free article] [PubMed]
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217. Shafat I, Ben Barak A, Postovsky S, Elhasid R, Vlodavsky I, Vlodavsky I, Ben Arush M. Heparanase levels are elevated in the plasma of pediatric cancer patients and correlate with response to anti-cancer treatment. Neoplasia. 2007;9:909–916. [PMC free article] [PubMed]
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219. Devy L, Rabbani SA, Stochl M, Ruskowski M, Mackie I, Naa L, Toews M, van Gool R, Chen J, Ley A, et al. PEGylated DX-1000: pharmacokinetics and anti-neoplastic activity of a specific plasmin inhibitor. Neoplasia. 2007;9:927–937. [PMC free article] [PubMed]
220. Huss WJ, Gray DR, Tavakoli K, Marmillion ME, Durham LE, Johnson MA, Greenberg NM, Smith GJ. Origin of androgen insensitive poorly-differentiated tumors in the transgenic adenocarcinoma of mouse prostate model (TRAMP) Neoplasia. 2007;9:938–950. [PMC free article] [PubMed]
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226. Lee KC, Bradley DA, Hussain M, Meyer CR, Chenevert TL, Jacobson JA, Johnson TD, Galban CJ, Rehemtulla A, Pienta KJ, et al. A feasibility study evaluating the functional diffusion map as a predictive imaging biomarker for detection of treatment response in a patient with metastatic prostate cancer to the bone. Neoplasia. 2007;9:1003–1011. [PMC free article] [PubMed]
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231. Crich SG, Lanzardo S, Alberti D, Belfiore S, Ciampa A, Giovenzana GB, Lovazzano C, Pagliarin R, Aime S. MRI detection of tumor cells by targeting LDL receptors with Gd-loaded LDL particles. Neoplasia. 2007;9:1046–1056. [PMC free article] [PubMed]
232. Smith JM, Stubbert LJ, Hamill JD, McKay BC. The contribution of transactivation subdomains 1 and 2 to p53-induced gene expression is heterogeneous but not subdomain-specific. Neoplasia. 2007;9:1057–1065. [PMC free article] [PubMed]
233. Sasaki T, Kitadai Y, Nakamura T, Kim J, Tsan RZ, Kuwai T, Langley RR, Fan D, Kim S, Fidler IJ. Inhibition of EGFR and VEGFR phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice. Neoplasia. 2007;9:1066–1077. [PMC free article] [PubMed]
234. Sarrabayrouse G, Synaeve C, Leveque K, Favre G, Tilkin-Mariamé AF. Statins stimulate in vitro membrane FasL expression and lymphocyte apoptosis through RhoA/ROCK pathway in murine melanoma cells. Neoplasia. 2007;9:1078–1090. [PMC free article] [PubMed]
235. Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S. IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype (CIMP) and p53. Neoplasia. 2007;9:1091–1098. [PMC free article] [PubMed]
236. Perera RM, Zoncu R, Johns TG, Pypaert M, Lee F, Mellman I, Old LJ, Toomre DK, Scott AM. Internalization, intracellular trafficking and biodistribution of monoclonal antibody 806: a novel anti-EGFR antibody. Neoplasia. 2007;9:1099–1110. [PMC free article] [PubMed]
237. Campos AC, Molognoni F, Melo FH, Galdieri LC, Carneiro CR, D'Almeida V, Correa M, Jasiulionis MG. Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation. Neoplasia. 2007;9:1111–1121. [PMC free article] [PubMed]
238. Phillips TM, Kim K, Vlashi E, McBride WH, Pajonk F. Effects of recombinant erythropoietin on breast cancer initiating cells. Neoplasia. 2007;9:1122–1129. [PMC free article] [PubMed]
239. Pham W, Xie J, Gore J. Tracking the migration of dendritic cells by in vivo optical imaging. Neoplasia. 2007;9:1130–1137. [PMC free article] [PubMed]
240. Ackerstaff E, Artemov D, Gillies RJ, Bhujwalla ZM. Hypoxia and the presence of human vascular endothelial cells affect prostate cancer cell invasion and metabolism. Neoplasia. 2007;9:1138–1151. [PMC free article] [PubMed]
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242. Harisinghani M, Ross R, Guimaraes A, Weissleder R. Utility of a new bolus injectable nanoparticle for clinical cancer staging. Neoplasia. 2007;9:1160–1165. [PMC free article] [PubMed]
243. Junker K, van Oers JM, Zwarthoff EC, Kania I, Schubert J, Hartmann A. Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations. Neoplasia. 2008;10:1–7. [PMC free article] [PubMed]
244. Crissey MA, Guo RJ, Fogt F, Li H, Katz JP, Silberg DG, Suh ER, Lynch JP. The homeodomain transcription factor Cdx1 does not behave as an oncogene in normal mouse intestine. Neoplasia. 2008;10:8–19. [PMC free article] [PubMed]
245. Tam NN, Szeto CY, Sartor MA, Medvedovic M, Ho SM. Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17β-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats. Neoplasia. 2008;10:20–40. [PMC free article] [PubMed]
246. Cai J, Niu X, Chen Y, Hu Q, Shi G, Wu H, Wang J, Yi J. Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis. Neoplasia. 2008;10:41–51. [PMC free article] [PubMed]
247. Yeh HH, Wu CH, Giri R, Kato K, Kohno K, Izumi H, Chou CY, Su WC, Liu HS. Oncogenic Ras-induced morphologic change is through MEK/ERK signaling pathway to downregulate Stat3 at a posttranslational level in NIH3T3 cells. Neoplasia. 2008;10:52–60. [PMC free article] [PubMed]
248. Rodrigues EG, Dobroff AS, Cavarsan CF, Paschoalin T, Nimrichter L, Mortara RA, Santos EL, Fazio MA, Miranda A, Daffre S, et al. Effective topical treatment of subcutaneous murine B16F10-Nex2 melanoma by the antimicrobial peptide gomesin. Neoplasia. 2008;10:61–68. [PMC free article] [PubMed]
249. Kim MK, Mason JM, Li CM, Berkofsky-Fessler W, Jiang L, Choubey D, Grundy PE, Tycko B, Licht JD. A pathologic link between Wilms tumor suppressor gene, WT1, and IFI16. Neoplasia. 2008;10:69–78. [PMC free article] [PubMed]
250. Yu J, Yu J, Cordero KE, Johnson MD, Ghosh D, Rae JM, Chinnaiyan AM, Lippman ME. A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival. Neoplasia. 2008;10:79–88. [PMC free article] [PubMed]
251. De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, et al. An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma. Neoplasia. 2008;10:89–98. [PMC free article] [PubMed]
252. Vojtechova M, Tureckova J, Kucerova D, Sloncova E, Vachtenheim J, Tuhackova Z. Regulation of mTORC1 signaling by Src kinase activity is Akt1-independent in RSV-transformed cells. Neoplasia. 2008;10:99–107. [PMC free article] [PubMed]
253. Banciu M, Metselaar JM, Schiffelers RM, Storm G. Antitumor activity of liposomal prednisolone phosphate depends on the presence of functional tumor-associated macrophages in tumor tissue. Neoplasia. 2008;10:108–117. [PMC free article] [PubMed]
254. Huang S, Chen Y, Podsypanina K, Li Y. Comparison of expression profiles of metastatic versus primary mammary tumors in MMTV-Wnt-1 and MMTV-Neu transgenic mice. Neoplasia. 2008;10:118–124. [PMC free article] [PubMed]
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256. Warner KA, Miyazawa M, Cordeiro MM, Love WJ, Pinsky MS, Neiva KG, Spalding AC, Nor JE. Endothelial cells enhance tumor cell invasion through a crosstalk mediated by CXC chemokine signaling. Neoplasia. 2008;10:131–139. [PMC free article] [PubMed]
257. Henkhaus RS, Roy UK, Cavallo-Medved D, Sloane BF, Gerner EW, Ignatenko NA. Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells. Neoplasia. 2008;10:140–148. [PMC free article] [PubMed]
258. Hwang JH, Smith CA, Salhia B, Rutka JT. The role of fascin in the migration and invasiveness of malignant glioma cells. Neoplasia. 2008;10:149–159. [PMC free article] [PubMed]
259. Yan M, Shen J, Person MD, Kuang X, Lynn WS, Atlas D, Wong PK. Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress. Neoplasia. 2008;10:160–167. [PMC free article] [PubMed]
260. Rosenow F, Ossig R, Thormeyer D, Gasmann P, Schluter K, Brunner G, Haier J, Eble JA. Integrins as antimetastatic targets of RGD-independent snake venom components in liver metastasis [corrected] Neoplasia. 2008;10:168–176. [PMC free article] [PubMed]
261. Tomlins SA, Laxman B, Varambally S, Cao X, Yu J, Helgeson BE, Cao Q, Prensner JR, Rubin MA, Shah RB, et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia. 2008;10:177–188. [PMC free article] [PubMed]
262. Lefranc F, Kiss R. The sodium pump α1 subunit as a potential target to combat apoptosis-resistant glioblastomas. Neoplasia. 2008;10:198–206. [PMC free article] [PubMed]
263. Foster PJ, Dunn EA, Karl KE, Snir JA, Nycz CM, Harvey AJ, Pettis RJ. Cellular magnetic resonance imaging: in vivo imaging of melanoma cells in lymph nodes of mice. Neoplasia. 2008;10:207–216. [PMC free article] [PubMed]
264. Craig DH, Downey C, Basson MD. SiRNA-mediated reduction of α-actinin-1 inhibits pressure-induced murine tumor cell wound implantation and enhances tumor-free survival. Neoplasia. 2008;10:217–222. [PMC free article] [PubMed]
265. Spankuch B, Steinhauser I, Wartlick H, Kurunci-Csacsko E, Strebhardt KI, Langer K. Downregulation of Plk1 expression by receptor-mediated uptake of antisense oligonucleotide-loaded nanoparticles. Neoplasia. 2008;10:223–234. [PMC free article] [PubMed]
266. Jiang W, Cazacu S, Xiang C, Zenklusen JC, Fine HA, Berens M, Armstrong B, Brodie C, Mikkelsen T. FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-κB signaling pathway. Neoplasia. 2008;10:235–243. [PMC free article] [PubMed]
267. Begley LA, Kasina S, Mehra R, Adsule S, Admon AJ, Lonigro RJ, Chinnaiyan AM, Macoska JA. CXCL5 promotes prostate cancer progression. Neoplasia. 2008;10:244–254. [PMC free article] [PubMed]
268. Sasaki M, Sakano S, Okayama N, Akao J, Hara T, Kawai Y, Ohmi C, Hinoda Y, Naito K. DNA repair gene polymorphisms may be associated with prognosis of upper urinary tract transitional cell carcinoma. Neoplasia. 2008;10:255–265. [PMC free article] [PubMed]
269. Ateeq B, Unterberger A, Szyf M, Rabbani SA. Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo. Neoplasia. 2008;10:266–278. [PMC free article] [PubMed]
270. Menschikowski M, Hagelgans A, Gussakovsky E, Kostka H, Paley EL, Siegert G. Differential expression of secretory phospholipases A2 in normal and malignant prostate cell lines: regulation by cytokines, cell signaling pathways, and epigenetic mechanisms. Neoplasia. 2008;10:279–286. [PMC free article] [PubMed]
271. Xiong H, Zhang ZG, Tian XQ, Sun DF, Liang QC, Zhang YJ, Lu R, Chen YX, Fang JY. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia. 2008;10:287–297. [PMC free article] [PubMed]
272. Perner S, Wagner PL, Demichelis F, Mehra R, Lafargue CJ, Moss BJ, Arbogast S, Soltermann A, Weder W, Giordano TJ, et al. EML4-ALK fusion lung cancer: a rare acquired event. Neoplasia. 2008;10:298–302. [PMC free article] [PubMed]
273. Chung YL, Troy H, Kristeleit R, Aherne W, Jackson LE, Atadja P, Griffiths JR, Judson IR, Workman P, Leach MO, et al. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia. 2008;10:303–313. [PMC free article] [PubMed]
274. Li Q, Mullins SR, Sloane BF, Mattingly RR. p21-Activated kinase 1 coordinates aberrant cell survival and pericellular proteolysis in a three-dimensional culture model for premalignant progression of human breast cancer. Neoplasia. 2008;10:314–329. [PMC free article] [PubMed]
275. Pahler JC, Tazzyman S, Erez N, Chen YY, Murdoch C, Nozawa H, Lewis CE, Hanahan D. Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia. 2008;10:329–340. [PMC free article] [PubMed]
276. van der Horst EH, Frank BT, Chinn L, Coxon A, Li S, Polesso F, Slavin A, Ruefli-Brasse A, Wesche H. The growth factor Midkine antagonizes VEGF signaling in vitro and in vivo. Neoplasia. 2008;10:340–347. [PMC free article] [PubMed]
277. Gil Z, Kelly KJ, Brader P, Shah JP, Fong Y, Wong RJ. Utility of a herpes oncolytic virus for the detection of neural invasion by cancer. Neoplasia. 2008;10:347–353. [PMC free article] [PubMed]
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279. Coppola JM, Bhojani MS, Ross BD, Rehemtulla A. A small-molecule furin inhibitor inhibits cancer cell motility and invasiveness. Neoplasia. 2008;10:363–370. [PMC free article] [PubMed]
280. Havens AM, Pedersen EA, Shiozawa Y, Ying C, Jung Y, Sun Y, Neeley C, Wang J, Mehra R, Keller ET, et al. An in vivo mouse model for human prostate cancer metastasis. Neoplasia. 2008;10:371–380. [PMC free article] [PubMed]
281. Mikhaylova M, Mori N, Wildes FB, Walczak P, Gimi B, Bhujwalla ZM. Hypoxia increases breast cancer cell-induced lymphatic endothelial cell migration. Neoplasia. 2008;10:380–389. [PMC free article] [PubMed]
282. Li C, Greenwood TR, Glunde K. Glucosamine-bound near-infrared fluorescent probes with lysosomal specificity for breast tumor imaging. Neoplasia. 2008;10:389–398. [PMC free article] [PubMed]
283. Wang S, Liu H, Ren L, Pan Y, Zhang Y. Inhibiting colorectal carcinoma growth and metastasis by blocking the expression of VEGF using RNA interference. Neoplasia. 2008;10:399–407. [PMC free article] [PubMed]
284. Cruz-Monserrate Z, O'Connor KL. Integrin α6β4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation. Neoplasia. 2008;10:408–417. [PMC free article] [PubMed]
285. Lorenzo PI, Saatcioglu F. Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation. Neoplasia. 2008;10:418–428. [PMC free article] [PubMed]
286. Mitra S, Foster TH. In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6. Neoplasia. 2008;10:429–438. [PMC free article] [PubMed]
287. Dong Z, Saliganan AD, Meng H, Nabha SM, Sabbota AL, Sheng S, Bonfil RD, Cher ML. Prostate cancer cell-derived urokinase-type plasminogen activator contributes to intraosseous tumor growth and bone turnover. Neoplasia. 2008;10:439–449. [PMC free article] [PubMed]
288. Junk DJ, Vrba L, Watts GS, Oshiro MM, Martinez JD, Futscher BW. Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia. 2008;10:450–461. [PMC free article] [PubMed]
289. Sticht C, Freier K, Knopfle K, Flechtenmacher C, Pungs S, Hofele C, Hahn M, Joos S, Lichter P. Activation of MAP kinase signaling through ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC) Neoplasia. 2008;10:462–470. [PMC free article] [PubMed]
290. Al-Romaih K, Sadikovic B, Yoshimoto M, Wang Y, Zielenska M, Squire JA. Decitabine-induced demethylation of 5′ CpG island in GADD45A leads to apoptosis in osteosarcoma cells. Neoplasia. 2008;10:471–480. [PMC free article] [PubMed]
291. Giusti I, D'Ascenzo S, Millimaggi D, Taraboletti G, Carta G, Franceschini N, Pavan A, Dolo V. Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles. Neoplasia. 2008;10:481–488. [PMC free article] [PubMed]
292. Kuwai T, Nakamura T, Sasaki T, Kim SJ, Fan D, Villares GJ, Zigler M, Wang H, Bar-Eli M, Kerbel RS, et al. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. Neoplasia. 2008;10:489–500. [PMC free article] [PubMed]
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301. Zuco V, Zunino F. Cyclic pifithrin-α sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. Neoplasia. 2008;10:587–596. [PMC free article] [PubMed]
302. Reddy RC, Srirangam A, Reddy K, Chen J, Gangireddy S, Kalemkerian GP, Standiford TJ, Keshamouni VG. Chemotherapeutic drugs induce PPAR-γ expression and show sequence-specific synergy with PPAR-γ ligands in inhibition of non-small cell lung cancer. Neoplasia. 2008;10:597–603. [PMC free article] [PubMed]
303. Baia GS, Stifani S, Kimura ET, McDermott MW, Pieper RO, Lal A. Notch activation is associated with tetraploidy and enhanced chromosomal instability in meningiomas. Neoplasia. 2008;10:604–612. [PMC free article] [PubMed]
304. Volk LD, Flister MJ, Bivens CM, Stutzman A, Desai N, Trieu V, Ran S. Nab-paclitaxel efficacy in the orthotopic model of human breast cancer is significantly enhanced by concurrent anti-vascular endothelial growth factor A therapy. Neoplasia. 2008;10:613–623. [PMC free article] [PubMed]
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306. Toma MI, Grosser M, Herr A, Aust DE, Meye A, Hoefling C, Fuessel S, Wuttig D, Wirth MP, Baretton GB. Loss of heterozygosity and copy number abnormality in clear cell renal cell carcinoma discovered by high-density affymetrix 10K single nucleotide polymorphism mapping array. Neoplasia. 2008;10:634–642. [PMC free article] [PubMed]
307. Privette LM, Weier JF, Nguyen HN, Yu X, Petty EM. Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpoint. Neoplasia. 2008;10:643–652. [PMC free article] [PubMed]
308. Siwko SK, Bu W, Gutierrez C, Lewis B, Jechlinger M, Schaffhausen B, Li Y. Lentivirus-mediated oncogene introduction into mammary cells in vivo induces tumors. Neoplasia. 2008;10:653–662. 651 p following 662. [PMC free article] [PubMed]
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310. Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, et al. High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF. Neoplasia. 2008;10:674–679. [PMC free article] [PubMed]
311. Ahlquist T, Bottillo I, Danielsen SA, Meling GI, Rognum TO, Lind GE, Dallapiccola B, Lothe RA. RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A. Neoplasia. 2008;10:680–686. 682 p following 686. [PMC free article] [PubMed]
312. Koletsa T, Kostopoulos I, Charalambous E, Christoforidou B, Nenopoulou E, Kotoula V. A splice variant of HER2 corresponding to Herstatin is expressed in the noncancerous breast and in breast carcinomas. Neoplasia. 2008;10:687–696. [PMC free article] [PubMed]
313. Ueno K, Hiura M, Suehiro Y, Hazama S, Hirata H, Oka M, Imai K, Dahiya R, Hinoda Y. Frizzled-7 as a potential therapeutic target in colorectal cancer. Neoplasia. 2008;10:697–705. [PMC free article] [PubMed]
314. Ruddell A, Harrell MI, Minoshima S, Maravilla KR, Iritani BM, White SW, Partridge SC. Dynamic contrast-enhanced magnetic resonance imaging of tumor-induced lymph flow. Neoplasia. 2008;10:706–713. 701 p following 713. [PMC free article] [PubMed]
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316. Brurberg KG, Gaustad JV, Mollatt CS, Rofstad EK. Temporal heterogeneity in blood supply in human tumor xenografts. Neoplasia. 2008;10:727–735. [PMC free article] [PubMed]
317. Yu LJ, Wu ML, Li H, Chen XY, Wang Q, Sun Y, Kong QY, Liu J. Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells. Neoplasia. 2008;10:736–744. [PMC free article] [PubMed]
318. Robey IF, Stephen RM, Brown KS, Baggett BK, Gatenby RA, Gillies RJ. Regulation of the Warburg effect in early-passage breast cancer cells. Neoplasia. 2008;10:745–756. [PMC free article] [PubMed]
319. Potter N, Karakoula A, Phipps KP, Harkness W, Hayward R, Thompson DN, Jacques TS, Harding B, Thomas DG, Palmer RW, et al. Genomic deletions correlate with underexpression of novel candidate genes at six loci in pediatric pilocytic astrocytoma. Neoplasia. 2008;10:757–772. [PMC free article] [PubMed]
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321. Colby JK, Klein RD, McArthur MJ, Conti CJ, Kiguchi K, Kawamoto T, Riggs PK, Pavone AI, Sawicki J, Fischer SM. Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression. Neoplasia. 2008;10:782–796. [PMC free article] [PubMed]
322. Hall CL, Dubyk CW, Riesenberger TA, Shein D, Keller ET, van Golen KL. Type I collagen receptor (α2β1) signaling promotes prostate cancer invasion through RhoC GTPase. Neoplasia. 2008;10:797–803. [PMC free article] [PubMed]
323. Levkoff LH, Marshall GP, II, Ross HH, Caldeira M, Reynolds BA, Cakiroglu M, Mariani CL, Streit WJ, Laywell ED. Bromodeoxyuridine inhibits cancer cell proliferation in vitro and in vivo. Neoplasia. 2008;10:804–816. [PMC free article] [PubMed]
324. Nevo I, Sagi-Assif O, Edry Botzer L, Amar D, Maman S, Kariv N, Leider-Trejo LE, Savelyeva L, Schwab M, Yron I, et al. Generation and characterization of novel local and metastatic human neuroblastoma variants. Neoplasia. 2008;10:816–827. [PMC free article] [PubMed]
325. Liu X, Shi Y, Woods KW, Hessler P, Kroeger P, Wilsbacher J, Wang J, Wang JY, Li C, Li Q, et al. Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression. Neoplasia. 2008;10:828–837. [PMC free article] [PubMed]
326. Williams PD, Lee JK, Theodorescu D. Molecular credentialing of rodent bladder carcinogenesis models. Neoplasia. 2008;10:838–846. [PMC free article] [PubMed]
327. Wang J, Yu W, Cai Y, Ren C, Ittmann MM. Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression. Neoplasia. 2008;10:847–856. [PMC free article] [PubMed]
328. Bhattacharya A, Toth K, Durrani FA, Cao S, Slocum HK, Chintala S, Rustum YM. Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts. Neoplasia. 2008;10:857–865. [PMC free article] [PubMed]
329. Hollander MC, Balogh AR, Liwanag J, Han W, Linnoila RI, Anver MR, Dennis PA. Strain-specific spontaneous and NNK-mediated tumorigenesis in Pten+/- mice. Neoplasia. 2008;10:866–872. [PMC free article] [PubMed]
330. Hetschko H, Voss V, Senft C, Seifert V, Prehn JH, Kogel D. BH3 mimetics reactivate autophagic cell death in anoxia-resistant malignant glioma cells. Neoplasia. 2008;10:873–885. [PMC free article] [PubMed]
331. Isenberg JS, Hyodo F, Ridnour LA, Shannon CS, Wink DA, Krishna MC, Roberts DD. Thrombospondin 1 and vasoactive agents indirectly alter tumor blood flow. Neoplasia. 2008;10:886–896. [PMC free article] [PubMed]
332. Liu W, Xie CC, Zhu Y, Li T, Sun J, Cheng Y, Ewing CM, Dalrymple S, Turner AR, Sun J, et al. Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer. Neoplasia. 2008;10:897–907. [PMC free article] [PubMed]
333. Chan MW, Huang YW, Hartman-Frey C, Kuo CT, Deatherage D, Qin H, Cheng AS, Yan PS, Davuluri RV, Huang TH, et al. Aberrant transforming growth factor β1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer. Neoplasia. 2008;10:908–919. [PMC free article] [PubMed]
334. Bonte D, Lindvall C, Liu H, Dykema K, Furge K, Weinreich M. Cdc7-Dbf4 kinase overexpression in multiple cancers and tumor cell lines is correlated with p53 inactivation. Neoplasia. 2008;10:920–931. [PMC free article] [PubMed]
335. Okazaki T, Ebihara S, Asada M, Yamanda S, Niu K, Arai H. Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis. Neoplasia. 2008;10:932–939. [PMC free article] [PubMed]
336. Genin O, Rechavi G, Nagler A, Ben-Itzhak O, Nazemi KJ, Pines M. Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment? Neoplasia. 2008;10:940–948. [PMC free article] [PubMed]
337. El Sheikh SS, Romanska HM, Abel P, Domin J, Lalani el N. Predictive value of PTEN and AR coexpression of sustained responsiveness to hormonal therapy in prostate cancer—a pilot study. Neoplasia. 2008;10:949–953. [PMC free article] [PubMed]
338. Scheper MA, Shirtliff ME, Meiller TF, Peters BM, Jabra-Rizk MA. Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells. Neoplasia. 2008;10:954–963. [PMC free article] [PubMed]
339. Park DC, Yeo SG, Wilson MR, Yerbury JJ, Kwong J, Welch WR, Choi YK, Birrer MJ, Mok SC, Wong KK. Clusterin interacts with paclitaxel and confer paclitaxel resistance in ovarian cancer. Neoplasia. 2008;10:964–972. [PMC free article] [PubMed]
340. Grochola LF, Greither T, Taubert HW, Moller P, Knippschild U, Udelnow A, Henne-Bruns D, Wurl P. Prognostic relevance of hTERT mRNA expression in ductal adenocarcinoma of the pancreas. Neoplasia. 2008;10:973–976. [PMC free article] [PubMed]
341. Chen T, Tang XD, Wan Y, Chen L, Yu ST, Xiong Z, Fang DC, Liang GP, Yang SM. HLA-A2-restricted cytotoxic T lymphocyte epitopes from human heparanase as novel targets for broad-spectrum tumor immunotherapy. Neoplasia. 2008;10:977–986. [PMC free article] [PubMed]
342. Ryzhov S, Novitskiy SV, Zaynagetdinov R, Goldstein AE, Carbone DP, Biaggioni I, Dikov MM, Feoktistov I. Host A(2B) adenosine receptors promote carcinoma growth. Neoplasia. 2008;10:987–995. [PMC free article] [PubMed]
343. Wiesner C, Nabha SM, Dos Santos EB, Yamamoto H, Meng H, Melchior SW, Bittinger F, Thuroff JW, Vessella RL, Cher ML, et al. C-kit and its ligand stem cell factor: potential contribution to prostate cancer bone metastasis. Neoplasia. 2008;10:996–1003. [PMC free article] [PubMed]
344. Liu B, Yu HM, Huang J, Hsu W. Co-opted JNK/SAPK signaling in Wnt/β-catenin-induced tumorigenesis. Neoplasia. 2008;10:1004–1013. [PMC free article] [PubMed]
345. Kischel P, Guillonneau F, Dumont B, Bellahcene A, Stresing V, Clezardin P, De Pauw EA, Castronovo V. Cell membrane proteomic analysis identifies proteins differentially expressed in osteotropic human breast cancer cells. Neoplasia. 2008;10:1014–1020. [PMC free article] [PubMed]
346. Weichert W, Denkert C, Noske A, Darb-Esfahani S, Dietel M, Kalloger SE, Huntsman DG, Kobel M. Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas. Neoplasia. 2008;10:1021–1027. [PMC free article] [PubMed]
347. Zhu Q, Tannenbaum S, Hegde P, Kane M, Xu C, Kurtzman SH. Noninvasive monitoring of breast cancer during neoadjuvant chemotherapy using optical tomography with ultrasound localization. Neoplasia. 2008;10:1028–1040. [PMC free article] [PubMed]
348. de Haas EC, di Pietro A, Simpson KL, Meijer C, Suurmeijer AJ, Lancashire LJ, Cummings J, de Jong S, de Vries EG, Dive C, et al. Clinical evaluation of M30 and M65 ELISA cell death assays as circulating biomarkers in a drug-sensitive tumor, testicular cancer. Neoplasia. 2008;10:1041–1048. [PMC free article] [PubMed]
349. Macher-Goeppinger S, Aulmann S, Wagener N, Funke B, Tagscherer KE, Haferkamp A, Hohenfellner M, Kim S, Autschbach F, Schirmacher P, et al. Decoy receptor 3 is a prognostic factor in renal cell cancer. Neoplasia. 2008;10:1049–1056. [PMC free article] [PubMed]
350. Bayani J, Paderova J, Murphy J, Rosen B, Zielenska M, Squire JA. Distinct patterns of structural and numerical chromosomal instability characterize sporadic ovarian cancer. Neoplasia. 2008;10:1057–1065. [PMC free article] [PubMed]
351. Perez JM, Grimm J, Josephson L, Weissleder R. Integrated nano-sensors to determine levels and functional activity of human telomerase. Neoplasia. 2008;10:1066–1072. [PMC free article] [PubMed]
352. Allen CE, Du J, Jiang B, Huang Q, Yakovich AJ, Barnard JA. Transformation by oncogenic Ras expands the early genomic response to transforming growth factor β in intestinal epithelial cells. Neoplasia. 2008;10:1073–1082. [PMC free article] [PubMed]
353. Romer MU, Larsen L, Offenberg H, Brunner N, Lademann UA. Plasminogen activator inhibitor 1 protects fibrosarcoma cells from etoposide-induced apoptosis through activation of the PI3K/Akt cell survival pathway. Neoplasia. 2008;10:1083–1091. [PMC free article] [PubMed]
354. Said NA, Elmarakby AA, Imig JD, Fulton DJ, Motamed K. SPARC ameliorates ovarian cancer-associated inflammation. Neoplasia. 2008;10:1092–1104. [PMC free article] [PubMed]
355. Das B, Antoon R, Tsuchida R, Lotfi S, Morozova O, Farhat W, Malkin D, Koren G, Yeger H, Baruchel S. Squalene selectively protects mouse bone marrow progenitors against cisplatin and carboplatin-induced cytotoxicity in vivo without protecting tumor growth. Neoplasia. 2008;10:1105–1119. [PMC free article] [PubMed]
356. Glogowska A, Pyka J, Kehlen A, Los M, Perumal P, Weber E, Cheng SY, Hoang-Vu C, Klonisch T. The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells. Neoplasia. 2008;10:1120–1130. [PMC free article] [PubMed]
357. Lincz LF, Mudge LM, Scorgie FE, Sakoff JA, Hamilton CS, Seldon M. Quantification of hTERT splice variants in melanoma by SYBR green real-time polymerase chain reaction indicates a negative regulatory role for the β deletion variant. Neoplasia. 2008;10:1131–1137. [PMC free article] [PubMed]
358. Li Q, Feldman RA, Radhakrishnan VM, Carey S, Martinez JD. Hsf1 is required for the nuclear translocation of p53 tumor suppressor. Neoplasia. 2008;10:1138–1145. [PMC free article] [PubMed]
359. Mehta GU, Shively SB, Duong H, Tran MG, Moncrief TJ, Smith JH, Li J, Edwards NA, Lonser RR, Zhuang Z, et al. Progression of epididymal maldevelopment into hamartoma-like neoplasia in VHL disease. Neoplasia. 2008;10:1146–1153. [PMC free article] [PubMed]
360. Schmieder M, Wolf S, Danner B, Stoehr S, Juchems MS, Wuerl P, Henne-Bruns D, Knippschild U, Hasel C, Kramer K. p16 expression differentiates high-risk gastrointestinal stromal tumor and predicts poor outcome. Neoplasia. 2008;10:1154–1162. [PMC free article] [PubMed]
361. Stasinopoulos I, Mori N, Bhujwalla ZM. The malignant phenotype of breast cancer cells is reduced by COX-2 silencing. Neoplasia. 2008;10:1162–1169. [PMC free article] [PubMed]
362. Ashkenazi R, Gentry SN, Jackson TL. Pathways to tumorigenesis—modeling mutation acquisition in stem cells and their progen. Neoplasia. 2008;10:1170–1182. [PMC free article] [PubMed]
363. Friboulet L, Pioche-Durieu C, Rodriguez S, Valent A, Souquère S, Ripoche H, Khabir A, Tsao TW, Bosq J, Lo KW, et al. Recurrent overexpression of c-IAP2 in EBV-associated nasopharyngeal carcinomas: critical role in resistance to toll-like receptor 3-mediated apoptosis. Neoplasia. 2008;10:1183–1194. [PMC free article] [PubMed]
364. Menschikowski M, Hagelgans A, Kostka H, Eisenhofer G, Siegert G. Involvement of epigenetic mechanisms in the regulation of secretory phospholipase A2 expression in Jurkat leukemia cells. Neoplasia. 2008;10:1195–1203. [PMC free article] [PubMed]
365. Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A. The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP. Neoplasia. 2008;10:1204–1212. [PMC free article] [PubMed]
366. Jones GN, Tep C, Towns WH, II, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS. Tissue-specific ablation of Prkar1a causes schwannomas by suppressing NF protein production. Neoplasia. 2008;10:1213–1221. [PMC free article] [PubMed]
367. Roschke AV, Glebov OK, Lababidi S, Gehlhaus KS, Weinstein JN, Kirsch IR. Chromosomal instability is associated with higher expression of genes implicated in EMT, cancer invasiveness and metastasis, and lower expression of genes involved in cell cycle checkpoints, DNA repair and chromatin maintenance. Neoplasia. 2008;10:1222–1230. [PMC free article] [PubMed]
368. Gallagher SJ, Thompson JF, Indsto J, Scurr LL, Lett M, Gao B, Dunleavey R, Mann GJ, Kefford RF, Rizos H. p16INK4a expression and absence of B-RAF are independent predictors of chemosensitivity in melanoma tumors. Neoplasia. 2008;10:1231–1239. [PMC free article] [PubMed]
369. Corsino PE, Davis BJ, Nørgaard PH, Parker NNT, Law M, Dunn W, Law BK. Mammary tumors initiated by constitutive Cdk2 activation contain an invasive basal-like component. Neoplasia. 2008;10:1240–1252. [PMC free article] [PubMed]
370. Gorringe KL, Choong DYH, Williams LH, Ramakrishna M, Sridhar A, Qiu W, Bearfoot JL, Campbell IG. Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer. Neoplasia. 2008;10:1253–1258. [PMC free article] [PubMed]
371. Landen CN, Kim T, Lin YG, Merritt WM, Kamat AA, Han LY, Spannuth WA, Nick AM, Jennnings NB, Kinch MS, et al. Tumor-selective response to antibody-mediated targeting of αvβ3 integrin in ovarian cancer. Neoplasia. 2008;10:1259–1267. [PMC free article] [PubMed]
372. Chesler L, Goldenberg DD, Collins R, Grimmer M, Kim GE, Tihan T, Nguyen K, Yakovenko S, Matthay KK, Weiss WA. Chemotherapy induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction. Neoplasia. 2008;10:1268–1274. [PMC free article] [PubMed]
373. Liu F, Chen Z, Wang J, Shao X, Cui Z, Yang C, Zhu Z, Xiong D. Overexpression of cell-surface cytokeratin 8 in multidrug-resistant MCF-7/MX cells enhances cell adhesion to the extracellular matrix. Neoplasia. 2008;10:1275–1284. [PMC free article] [PubMed]
374. Varambally S, Laxman B, Mehra R, Cao Q, Dhanasekaran SM, Tomlins SA, Granger J, Vellaichamy A, Sreekumar A, Yu J, et al. Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer. Neoplasia. 2008;10:1285–1294. [PMC free article] [PubMed]
375. Schneider A, Younis RH, Gutkind JS. Hypoxia-induced energy stress inhibits the mTOR pathway by activating an AMPK/REDD1 signaling axis in head and neck squamous cell carcinoma. Neoplasia. 2008;10:1295–1302. [PMC free article] [PubMed]
376. Elia U, Flescher E. PI3K/Akt pathway activation attenuates the cytotoxic effect of methyl jasmonate towards sarcoma cells. Neoplasia. 2008;10:1303–1313. [PMC free article] [PubMed]
377. Mathieu V, Neve ND, Mercier ML, Dewelle J, Gaussin J, Dehaux M, Kiss R, LeFranc F. Combining bevacizumab with temozolomide increases the anti-tumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model. Neoplasia. 2008;10 [PMC free article] [PubMed]
378. Calzolari F, Appolloni I, Tutucci E, Caviglia S, Terrile M, Corte G, Malatesta P. Tumor progression and oncogene addiction in a PDGF-B-induced model of gliomagenesis. Neoplasia. 2008;10 [PMC free article] [PubMed]
379. Jiang W, Xiang C, Cazacu S, Brodie C, Mikkelsen T. Insulin-like growth factor binding protein 7 (IGFBP-7) mediates glioma cell growth and migration. Neoplasia. 2008;10 [PMC free article] [PubMed]
380. Li Q, Mattingly RR. Restoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast epithelial cells. Neoplasia. 2008;10 [PMC free article] [PubMed]
381. Rowe A, Weiske J, Kramer TS, Huber O, Jackson P. Phorbol ester enhances KAI1 transcription by recruiting Tip60/Pontin complexes. Neoplasia. 2008;10 [PMC free article] [PubMed]
382. Sprenger CCT, Drivdahl RH, Woodke LB, Eyman D, Reed MR, Carter WG, Plymate S. Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells. Neoplasia. 2008;10 [PMC free article] [PubMed]
383. Ogbomo H, Michaelis M, Klassert D, Doerr HW, Cinatl J. Resistance of cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells. Neoplasia. 2008;10 [PMC free article] [PubMed]
384. Chen JY, Hung C, Huang K, Chen Y, Liu S, Chiang W, Chen H, Yen C, Wu Y, Ko J, et al. Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma. Neoplasia. 2008;10 [PMC free article] [PubMed]
385. Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, Lohuizen MV, Dlugosz A. Bmi1 is required for Hedgehog-pathway driven medulloblastoma expansion. Neoplasia. 2008;10 [PMC free article] [PubMed]
386. Grange C, Stefania L, Cavallo F, Camussi G, Bussolati B. Sca-1 identifies the tumor initiating cells in mammary tumors of BALB-NEUT transgenic mice. Neoplasia. 2008;10 [PMC free article] [PubMed]
387. Kim HK, Zhang H, Li H, Wu T, Swisher S, He D, Wu L, Xu J, Elmets CA, Athar M, et al. Slit2 inhibits the growth and metastasis of fibrosarcoma and squamous cell carcinoma. Neoplasia. 2008;10 [PMC free article] [PubMed]
388. Sangha N, Wu R, Kuick R, Powers S, Mu D, Fiander D, Yuen K, Katabuchi H, Tashiro H, Fearon ER, et al. Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations. Neoplasia. 2008;10 [PMC free article] [PubMed]
389. Tamimi Y, Ekuere U, Laughton N, Milanovic A, Grundy P. WNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesis. Neoplasia. 2008;10 [PMC free article] [PubMed]
390. Tilborg GAF, Mulder WJM, Schaft DKJ, Reutelingsperger CPM, Griffioen AW, Strijkers GJ, Nicolay K. Improved MR molecular imaging of tumor angiogenesis by avidin-induced clearance of non-bound bimodal liposomes. Neoplasia. 2008;10 [PMC free article] [PubMed]
391. Triplett AA, Montagna CM, Wagner K. A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis. Neoplasia. 2008;10 [PMC free article] [PubMed]
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