Cell cycle–regulated genes with characterized functions. Two hundred ninety-seven of the cell cycle–regulated genes are grouped by both function and phase of peak expression. Several functional groups are split into subgroups, which reflect the nature of the function. Those highlighted in red were previously known to be cell cycle regulated. Many functional categories display strong biases toward gene expression during particular intervals of the cell cycle. Obvious examples include genes involved in DNA synthesis and DNA repair (G1), mating (M, M/G1, and G1), chromatin structure (G1 and S), and methionine biosynthesis (S and G2).
Articles from Molecular Biology of the Cell are provided here courtesy of
American Society for Cell Biology