Because of its high prevalence and its substantial effect, depression is a major contributor to the burden of illness in the older population. Its effect on function, quality of life, and use of medical services is severe. The presence of depression is associated with increased healthcare costs,
1 worse outcomes after acute medical events such as hip fracture
2,3 and stroke,
4,5 decline in physical function,
6,7 and poorer survival of elderly individuals.
8 Although many efforts have been made to promote the recognition of depression and its optimal care in the elderly,
9 current nationally representative data on patterns of identification and treatment are scarce, and rapid change in healthcare systems and treatment patterns has made many earlier analyses obsolete.
Many prior studies have called attention to underdiagnosis of depression among the elderly.
9–12 Diagnosis of depression in this population can be difficult,
13–16 and patients who seek help are likely to go to their regular primary care physician rather than a mental health specialist.
17–19 General practice physicians,
20,21 who often see mental health referral as unnecessary
22,23 and report a high level of confidence in their ability to manage antidepressant therapy for depressed elderly persons, prescribe the majority of psychotropics for the elderly.
24Even when diagnosed, older individuals often do not receive appropriate treatment.
9,25,26 Despite the availability of a basic level of health coverage through Medicare, older persons face particular barriers to care that can create added risk of nontreatment or undertreatment.
9 They may be particularly disinclined to view their distress as a medical problem. If they rely on Medicare alone for health coverage, cost barriers may be significant, because Medicare does not cover most prescription drug use and imposes high copayments for mental health specialty services such as psychotherapy (50%, vs 20% for other Part B services). For disabled Medicare beneficiaries with a different psychiatric condition (schizophrenia), a comparison of Medicare-only to dually eligible Medicare-Medicaid beneficiaries using Medicare Current Beneficiary Survey (MCBS) data found that those with Medicare only received less-appropriate patterns of treatment, suggesting that these patients experienced more barriers to care.
27Medical comorbidities may motivate undertreatment in the elderly because of physician concerns about side effects of antidepressants. Such concerns may have declined because of the availability of newer medications, such as selective serotonin-reuptake inhibitors (SSRIs), which have lower side-effect profiles. Almost 80% of Maryland family physicians surveyed in 1997 named an SSRI as their first-line medication for treating depression in the elderly,
24 but data from 1993 to 1994, 5 to 6 years after the introduction of fluoxetine, showed that generalists were still substantially underusing SSRIs.
28The two major recognized treatment modalities for depression are antidepressants and psychotherapy. A 1991 National Institutes of Health consensus panel supported the efficacy of psychotherapy for late-life depression, and a 1997 update report found that newer evidence continued to support these findings, with new reports of the utility of a variety of approaches, alone or in combination with drug treatment.
9 Antidepressant therapy is the mainstay of medical treatment for depression and has been shown to be safe and efficacious in the medically ill
29–34 and the elderly.
35,36 Rates of efficacy are similar across classes of antidepressants (e.g., tricyclic antidepressants versus SSRIs), with 60% to 80% of patients responding to treatment.
9 The elderly tend to tolerate SSRIs better than tricyclics, and dropout rates in clinical trials of SSRIs have been shown to be one-third to one-half those of patients treated with tricyclic antidepressants.
9In the elderly, there has been particularly inadequate attention to understanding the factors that predict use of available treatments. Especially scarce are large, nationally representative samples of the elderly. Findings on treatment of psychiatric disorders in other populations cannot be assumed to generalize to the elderly and disabled population, whose mental healthcare needs are particularly likely to be complicated by physical comorbidities and functional limitations. As previously reported,
37 factors affecting access to care include predisposing, enabling, and need (illness) variables. If access is equitable, one would anticipate finding that need factors principally predict treatment, whereas predisposing and, particularly, enabling factors would play minimal roles. As applied here, predisposing factors for depression treatment include age, race, and education; enabling factors include income, supplemental insurance coverage, and marital status; and need factors include such characteristics as health status, functional status, and severity. Given Medicare's limitations on pharmaceutical and mental health coverage, it is particularly important to determine the effect of supplemental coverage or lack thereof.
Thus, there is a need for better current information on trends in diagnosis and treatment of depression in older persons and on the extent of socioeconomic disparities in depression treatment for this population. Two questions, especially, are important. To what extent has identification and treatment of depression increased in the elderly in recent years? To what extent do socioeconomic factors such as the presence of supplementary insurance affect treatment?