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Logo of brjsmedBritish Journal of Sports MedicineVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
Br J Sports Med. 2007 August; 41(8): e5.
PMCID: PMC2465416


This review article provides a good insight into different aspects of tissue engineering for tendon repair. Tissue engineering offers the potential to improve the quality of tendon tissue during the healing process, and may provide a more effective approach to the treatment of injuries to tendons than traditional methods. Application of growth factors, gene transfer techniques, cell therapy and cell‐matrix composites has shown to affect the process of tendon healing. The benefits of using mesenchymal stem cells on a three‐dimensional biological matrix have been shown. Tissue engineering also includes mechanical manipulation of tissue environments to accelerate cell differentiation and to improve matrix formation. The authors, however, do not show the potential clinical applications. Thus, the reader is not informed on what is experimental and what is possible in the clinical setting at present.

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