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The use of computer‐based neurocognitive testing has become increasingly popular throughout the field of sports medicine. Given the rapid dissemination of computer‐based systems, increasingly specific questions have emerged regarding the interpretation of test results and the factors that may or may not influence test performance in a given athlete. This is an important issue as athletes may undergo post‐concussion testing in different situations and at different times after injury. An understanding of how specific test conditions affect performance is important in interpreting test results. This paper evaluates the effects of exercise on one test of neurocognitive functioning (IMmediate Post‐concussion Assessment and Cognitive Testing (ImPACT)). The authors found that the Verbal Memory Composite score of ImPACT was affected by maximal exercise. Therefore, clinicians and researchers should take care to perform post‐injury evaluations after a period of rest and not immediately after strenuous exercise.