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Ulster Med J. 2001 May; 70(1): 15–18.
PMCID: PMC2449207

Double contrast barium enema and colorectal carcinoma: sensitivity and potential role in screening.

Abstract

To establish the sensitivity of double contrast barium enema (DCBE) for detection of colorectal carcinoma in a tertiary referral centre and consider its possible role as a suitable imaging method in screening for this disease. A total of 160 patients with a histopathologically proven diagnosis of colorectal carcinoma over a two year period were reviewed. Subsequently 112 of the 160 patients were identified as having undergone DCBE, the results of which were analysed to determine its sensitivity for detecting colorectal carcinoma. Colorectal carcinoma was missed in 4 of the 112 barium enemas performed. This corresponds to a sensitivity of 96.5% with a false negative rate of 3.5%. The Dukes Classification in these 4 cases showed that Dukes stage B, C and D were missed, with tumours located in the right and the sigmoid colon. The mean delay to operation in these four cases was 6 weeks. Our study correlates with previous studies showing a false negative rate for DCBE of 3.5%. Colonoscopy also fails to detect small numbers of tumours with false negative rates reported as high as 10%. We suggest that double contrast barium enema should be effective as a screening method in any future colorectal cancer screening program.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Eddy DM. Screening for colorectal cancer. Ann Intern Med. 1990 Sep 1;113(5):373–384. [PubMed]
  • Ott DJ, Scharling ES, Chen YM, Wu WC, Gelfand DW. Barium enema examination: sensitivity in detecting colonic polyps and carcinomas. South Med J. 1989 Feb;82(2):197–200. [PubMed]
  • Gazelle GS, McMahon PM, Scholz FJ. Screening for colorectal cancer. Radiology. 2000 May;215(2):327–335. [PubMed]
  • Johnson CD, Carlson HC, Taylor WF, Weiland LP. Barium enemas of carcinoma of the colon: sensitivity of double- and single-contrast studies. AJR Am J Roentgenol. 1983 Jun;140(6):1143–1149. [PubMed]
  • Beggs I, Thomas BM. Diagnosis of carcinoma of the colon by barium enema. Clin Radiol. 1983 Jul;34(4):423–425. [PubMed]
  • Fork FT, Lindström C, Ekelund G. Double contrast examination in carcinoma of the colon and rectum. A prospective clinical series. Acta Radiol Diagn (Stockh) 1983;24(3):177–188. [PubMed]
  • Fork FT. Radiographic findings in overlooked colon carcinomas. A retrospective analysis. Acta Radiol. 1988 May-Jun;29(3):331–336. [PubMed]
  • Anderson N, Cook HB, Coates R. Colonoscopically detected colorectal cancer missed on barium enema. Gastrointest Radiol. 1991 Spring;16(2):123–127. [PubMed]

Articles from The Ulster Medical Journal are provided here courtesy of Ulster Medical Society