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Ulster Med J. 1993 October; 62(2): 141–144.
PMCID: PMC2449037

Huntington disease in County Donegal: epidemiological trends over four decades.


The prevalence rate of Huntington disease in County Donegal between 1961 and 1991 showed a decrease from 4.4 to 1.6 per 100,000 population. Emigration and reduction in family size probably account for the progressive decline in prevalence. Over the same time period in the rest of Europe, prevalence has declined only gradually, or has remained static.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Morrison PJ. Trinucleotide repeat repeat repeat. Lancet. 1993 Aug 14;342(8868):385–386. [PubMed]
  • Harper PS. The epidemiology of Huntington's disease. Hum Genet. 1992 Jun;89(4):365–376. [PubMed]
  • Quarrell OW, Tyler A, Jones MP, Nordin M, Harper PS. Population studies of Huntington's disease in Wales. Clin Genet. 1988 Mar;33(3):189–195. [PubMed]
  • LYON RL. Huntington's chorea in the Moray Firth area. Br Med J. 1962 May 12;1(5288):1301–1306. [PMC free article] [PubMed]

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