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J Biomol Tech. 1999 March; 10(1): 21–40.
PMCID: PMC2291579

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Selected References

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  • Lander ES. The new genomics: global views of biology. Science. 1996 Oct 25;274(5287):536–539. [PubMed]
  • Evangelista C, Lockshon D, Fields S. The yeast two-hybrid system: prospects for protein linkage maps. Trends Cell Biol. 1996 May;6(5):196–199. [PubMed]
  • Fromont-Racine M, Rain JC, Legrain P. Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat Genet. 1997 Jul;16(3):277–282. [PubMed]
  • Guarente L. Strategies for the identification of interacting proteins. Proc Natl Acad Sci U S A. 1993 Mar 1;90(5):1639–1641. [PubMed]
  • Adams SR, Harootunian AT, Buechler YJ, Taylor SS, Tsien RY. Fluorescence ratio imaging of cyclic AMP in single cells. Nature. 1991 Feb 21;349(6311):694–697. [PubMed]
  • Chien CT, Bartel PL, Sternglanz R, Fields S. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9578–9582. [PubMed]
  • Fields S, Song O. A novel genetic system to detect protein-protein interactions. Nature. 1989 Jul 20;340(6230):245–246. [PubMed]
  • Gyuris J, Golemis E, Chertkov H, Brent R. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell. 1993 Nov 19;75(4):791–803. [PubMed]
  • Johnsson N, Varshavsky A. Split ubiquitin as a sensor of protein interactions in vivo. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10340–10344. [PubMed]
  • Deonarain MP, Rowlinson-Busza G, George AJ, Epenetos AA. Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting. Protein Eng. 1997 Jan;10(1):89–98. [PubMed]
  • Kaufman RJ, Davies MV, Pathak VK, Hershey JW. The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs. Mol Cell Biol. 1989 Mar;9(3):946–958. [PMC free article] [PubMed]
  • Kunkel TA, Roberts JD, Zakour RA. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 1987;154:367–382. [PubMed]
  • Stammers DK, Champness JN, Beddell CR, Dann JG, Eliopoulos E, Geddes AJ, Ogg D, North AC. The structure of mouse L1210 dihydrofolate reductase-drug complexes and the construction of a model of human enzyme. FEBS Lett. 1987 Jun 22;218(1):178–184. [PubMed]
  • Appleman JR, Prendergast N, Delcamp TJ, Freisheim JH, Blakley RL. Kinetics of the formation and isomerization of methotrexate complexes of recombinant human dihydrofolate reductase. J Biol Chem. 1988 Jul 25;263(21):10304–10313. [PubMed]
  • Oefner C, D'Arcy A, Winkler FK. Crystal structure of human dihydrofolate reductase complexed with folate. Eur J Biochem. 1988 Jun 1;174(2):377–385. [PubMed]
  • Bystroff C, Kraut J. Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding. Biochemistry. 1991 Feb 26;30(8):2227–2239. [PubMed]
  • Perry KM, Onuffer JJ, Gittelman MS, Barmat L, Matthews CR. Long-range electrostatic interactions can influence the folding, stability, and cooperativity of dihydrofolate reductase. Biochemistry. 1989 Sep 19;28(19):7961–7968. [PubMed]
  • Bullerjahn AM, Freisheim JH. Site-directed deletion mutants of a carboxyl-terminal region of human dihydrofolate reductase. J Biol Chem. 1992 Jan 15;267(2):864–870. [PubMed]
  • Buchwalder A, Szadkowski H, Kirschner K. A fully active variant of dihydrofolate reductase with a circularly permuted sequence. Biochemistry. 1992 Feb 18;31(6):1621–1630. [PubMed]
  • Chen X, Rambo R, Matthews CR. Amino acid replacements can selectively affect the interaction energy of autonomous folding units in the alpha subunit of tryptophan synthase. Biochemistry. 1992 Mar 3;31(8):2219–2223. [PubMed]
  • Prevost M, Wodak SJ, Tidor B, Karplus M. Contribution of the hydrophobic effect to protein stability: analysis based on simulations of the Ile-96----Ala mutation in barnase. Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10880–10884. [PubMed]
  • Kellis JT, Jr, Nyberg K, Sali D, Fersht AR. Contribution of hydrophobic interactions to protein stability. Nature. 1988 Jun 23;333(6175):784–786. [PubMed]
  • Kellis JT, Jr, Nyberg K, Fersht AR. Energetics of complementary side-chain packing in a protein hydrophobic core. Biochemistry. 1989 May 30;28(11):4914–4922. [PubMed]
  • Dicker AP, Waltham MC, Volkenandt M, Schweitzer BI, Otter GM, Schmid FA, Sirotnak FM, Bertino JR. Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11797–11801. [PubMed]
  • Hussain A, Lewis D, Yu M, Melera PW. Construction of a dominant selectable marker using a novel dihydrofolate reductase. Gene. 1992 Mar 15;112(2):179–188. [PubMed]
  • Simonsen CC, Levinson AD. Isolation and expression of an altered mouse dihydrofolate reductase cDNA. Proc Natl Acad Sci U S A. 1983 May;80(9):2495–2499. [PubMed]
  • Thillet J, Absil J, Stone SR, Pictet R. Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim. J Biol Chem. 1988 Sep 5;263(25):12500–12508. [PubMed]
  • Schweitzer BI, Srimatkandada S, Gritsman H, Sheridan R, Venkataraghavan R, Bertino JR. Probing the role of two hydrophobic active site residues in the human dihydrofolate reductase by site-directed mutagenesis. J Biol Chem. 1989 Dec 5;264(34):20786–20795. [PubMed]
  • Banerjee D, Schweitzer BI, Volkenandt M, Li MX, Waltham M, Mineishi S, Zhao SC, Bertino JR. Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance. Gene. 1994 Feb 25;139(2):269–274. [PubMed]
  • Jonnalagadda S, Butt TR, Monia BP, Mirabelli CK, Gotlib L, Ecker DJ, Crooke ST. Multiple (alpha-NH-ubiquitin)protein endoproteases in cells. J Biol Chem. 1989 Jun 25;264(18):10637–10642. [PubMed]
  • Wilkinson KD, Lee KM, Deshpande S, Duerksen-Hughes P, Boss JM, Pohl J. The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. Science. 1989 Nov 3;246(4930):670–673. [PubMed]
  • Johnsson N, Varshavsky A. Ubiquitin-assisted dissection of protein transport across membranes. EMBO J. 1994 Jun 1;13(11):2686–2698. [PubMed]

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