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Table 4

Predictors of symptom severity for days 2–4 after seeing the doctor.

β (95% CI)Adjusted βa (95% CI)P-value
Clinical assessment
 Prior duration, days0.00 (−0.01 to 0.01)0.00 (−0.005 to 0.01)0.34
 History of fever0.44 (0.26 to 0.62)0.06 (−0.08 to 0.19)0.42
 Green–coloured sputum0.12 (−0.06 to 0.29)−0.04 (−0.17 to 0.10)0.34
 Sore throat0.11 (−0.08 to 0.30)0.01 (−0.13 to 0.15)0.86
 Runny nose0.06 (−0.12 to 0.25)−0.06 (−0.19 to 0.08)0.43
 Prolonged expiration0.31 (−0.21 to 0.84)0.04 (−0.39 to 0.46)0.87
 Respiration rate, ≥20/min0.07 (−0.14 to 0.27)−0.04 (−0.20 to 0.11)0.60
 Temperature, ≥37.0°C−0.06 (−0.25 to 0.13)−0.07 (−0.21 to 0.07)0.33
 Coarse crepitations0.09 (−0.16 to 0.33)0.02 (−0.16 to 0.20)0.83
 Wheeze0.18 (−0.09 to 0.44)−0.04 (−0.23 to 0.16)0.70
 Fine crepitations−0.04 (−0.57 to 0.49)0.16 (−0.22 to 0.54)0.42
 Smoker0.33 (0.10 to 0.56)0.02 (−0.16 to 0.20)0.80

Age
 Older age, ≥60 years−0.53 (−0.31 to 0.75)−0.17 (−0.01 to −0.34)0.043
 Children, <16 years−0.58 (−0.35 to −0.80)−0.23 (−0.06; to −0.41)0.008b

Symptoms on day 1
 Cough0.36 (0.29 to 0.43)0.03 (−0.03 to 0.10)0.33
 Sputum0.30 (0.25 to 0.35)0.15 (0.10 to 0.19)<0.001b
 Short of breath0.31 (0.25 to 0.36)0.12 (0.07 to 0.17)<0.001b
 Sleep0.28 (0.24 to 0.33)0.11 (0.07 to 0.16)<0.001b
 Restriction of activities0.40 (0.35 to 0.45)0.17 (0.11 to 0.24)<0.001b
 Unwell0.40 (0.34 to 0.45)0.10 (0.03 to 0.17)0.003b

The β estimates are the estimate of the number of days' difference in duration attributable to each variable.

aThe estimates for each variable controls for the effects of the other variables and the randomised interventions.
bP-value is significant at ≤0.01.