PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of brjcancerBJC HomepageBJC Advance online publicationBJC Current IssueSubmitting an article to BJCWeb feeds
 
Br J Cancer. 1997; 75(7): 1061–1065.
PMCID: PMC2222746

Mucoid breast carcinomas: histology and prognosis.

Abstract

In a series of 73 patients with mucoid breast carcinomas treated at Guy's Hospital between 1973 and 1989, 24 (33%) patients had pure mucoid lesions and 49 (67%) had mixed mucoid carcinomas. The patients with pure mucoid cancers had significantly smaller tumours and, among those in whom an axillary dissection was performed, mixed mucoid cancers were more likely to be associated with axillary nodal metastases (46% vs 14%). After long-term follow-up of 64 patients, both relapse-free and overall survival were significantly better for those with pure mucoid carcinomas, for whom the 10-year actuarial overall survival was 100%. The overall proportion of the tumour that was mucoid was also positively associated with a more favourable prognosis in patients with mixed tumours. With such a good prognosis, patients with pure mucoid carcinomas may not require systemic adjuvant therapy after adequate primary treatment.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (857K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • André S, Cunha F, Bernardo M, Meneses e Sousa J, Cortez F, Soares J. Mucinous carcinoma of the breast: a pathologic study of 82 cases. J Surg Oncol. 1995 Mar;58(3):162–167. [PubMed]
  • Capella C, Eusebi V, Mann B, Azzopardi JG. Endocrine differentiation in mucoid carcinoma of the breast. Histopathology. 1980 Nov;4(6):613–630. [PubMed]
  • Clayton F. Pure mucinous carcinomas of breast: morphologic features and prognostic correlates. Hum Pathol. 1986 Jan;17(1):34–38. [PubMed]
  • Coady AT, Shousha S, Dawson PM, Moss M, James KR, Bull TB. Mucinous carcinoma of the breast: further characterization of its three subtypes. Histopathology. 1989 Dec;15(6):617–626. [PubMed]
  • Elston CW, Gresham GA, Rao GS, Zebro T, Haybittle JL, Houghton J, Kearney G. The cancer research campaign (King's/Cambridge trial for early breast cancer: clinico-pathological aspects. Br J Cancer. 1982 May;45(5):655–669. [PMC free article] [PubMed]
  • Ferguson DJ, Anderson TJ, Wells CA, Battersby S. An ultrastructural study of mucoid carcinoma of the breast: variability of cytoplasmic features. Histopathology. 1986 Dec;10(12):1219–1230. [PubMed]
  • Maluf HM, Koerner FC. Solid papillary carcinoma of the breast. A form of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma. Am J Surg Pathol. 1995 Nov;19(11):1237–1244. [PubMed]
  • MELAMED MR, ROBBINS GF, FOOTE FW., Jr Prognostic significance of gelatinous mammary carcinoma. Cancer. 1961 Jul-Aug;14:699–704. [PubMed]
  • NORRIS HJ, TAYLOR HB. PROGNOSIS OF MUCINOUS (GELATINOUS) CARCINOMA OF THE BREAST. Cancer. 1965 Jul;18:879–885. [PubMed]
  • Pereira H, Pinder SE, Sibbering DM, Galea MH, Elston CW, Blamey RW, Robertson JF, Ellis IO. Pathological prognostic factors in breast cancer. IV: Should you be a typer or a grader? A comparative study of two histological prognostic features in operable breast carcinoma. Histopathology. 1995 Sep;27(3):219–226. [PubMed]
  • Rasmussen BB. Human mucinous breast carcinomas and their lymph node metastases. A histological review of 247 cases. Pathol Res Pract. 1985 Oct;180(4):377–382. [PubMed]
  • Rasmussen BB, Rose C, Thorpe SM, Andersen KW, Hou-Jensen K. Argyrophilic cells in 202 human mucinous breast carcinomas. Relation to histopathologic and clinical factors. Am J Clin Pathol. 1985 Dec;84(6):737–740. [PubMed]
  • Rasmussen BB, Rose C, Christensen IB. Prognostic factors in primary mucinous breast carcinoma. Am J Clin Pathol. 1987 Feb;87(2):155–160. [PubMed]
  • Scopsi L, Andreola S, Pilotti S, Bufalino R, Baldini MT, Testori A, Rilke F. Mucinous carcinoma of the breast. A clinicopathologic, histochemical, and immunocytochemical study with special reference to neuroendocrine differentiation. Am J Surg Pathol. 1994 Jul;18(7):702–711. [PubMed]
  • Silverberg SG, Kay S, Chitale AR, Levitt SH. Colloid carcinoma of the breast. Am J Clin Pathol. 1971 Mar;55(3):355–363. [PubMed]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK