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Figure 4.

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HIV-1 RNA is localized in the organized lymphoid follicles of the GI tract in subjects with acute and early HIV-1 infection. In situ hybridization was performed using a 35S-labeled, single stranded antisense RNA probe as described in Materials and Methods. Cells expressing HIV-1 RNA (arrows) are present in the germinal center and T cell zone. A magnification of 40.

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