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J Bacteriol. 1979 September; 139(3): 1068–1071.
PMCID: PMC218059

Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast.


The extrachromosomal psi+ determinant in the yeast Saccharomyces cerevisiae enhanced the expression of Mendelian UAA suppressors by 6- to 10-fold. The psi+ determinant by itself is a weak UAA suppressor that caused the production of approximately 1% of the normal level of iso-1-cytochrome c in a strain containing the UAA mutation cycl-72.

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