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Logo of jroyalcgpracBJGP at RCGPBJGP at PubMed CentralJ R Coll Gen Pract at PubMed CentralRCGP homepage
J R Coll Gen Pract. 1979 July; 29(204): 391–396.
PMCID: PMC2159233

Compliance with prescribed medicines: a study of elderly patients in the community


Compliance with regular medicine taking has been assessed in 81 patients, aged 65 and over, living at home. Interview assessment, home tablet count, and retrospective review of general practice prescription record cards provided three indices of compliance.

Deviation by more than 10 per cent from absolute adherence to the prescription was found in 53 per cent of all tablet counts and was significantly more common in women than in men. Errors were also more common when medicines were to be taken more than once daily.

The compliance index obtained by inspection of prescription records correlated closely with the index calculated from tablet counts (rs = 0·68; p < 0·001) for 129 separate medicines taken regularly. Poor compliance with an individual medicine could be predicted accurately in 66 per cent of cases. A combination of prescription record inspection and interview assessment increased the accuracy of this prediction to 86 per cent.

These findings suggest that, using simple methods, the level of compliance can be accurately predicted in a substantial number of elderly patients at home.

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Selected References

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  • Crooks J, Shepherd AM, Stevenson IH. Drugs and the elderly. The nature of the problem. Health Bull (Edinb) 1975 Sep;33(5):222–227. [PubMed]
  • Drury VW, Wade OL, Woolf E. Following advice in general practice. J R Coll Gen Pract. 1976 Oct;26(171):712–718. [PMC free article] [PubMed]
  • Gatley MS. To be taken as directed. J R Coll Gen Pract. 1968 Jul;16(1):39–44. [PMC free article] [PubMed]
  • Gibson II, O'Hare MO. Prescription of drugs for old people at home. Gerontol Clin (Basel) 1968;10(5):271–280. [PubMed]
  • Parkin DM, Henney CR, Quirk J, Crooks J. Deviation from prescribed drug treatment after discharge from hospital. Br Med J. 1976 Sep 18;2(6037):686–688. [PMC free article] [PubMed]
  • Qureshi KN, Hodkinson HM. Evaluation of a ten-question mental test in the institutionalized elderly. Age Ageing. 1974 Aug;3(3):152–157. [PubMed]
  • SCHWARTZ D, WANG M, ZEITZ L, GOSS ME. Medication errors made by elderly, chronically ill patients. Am J Public Health Nations Health. 1962 Dec;52:2018–2029. [PubMed]
  • Skegg DC, Doll R, Perry J. Use of medicines in general practice. Br Med J. 1977 Jun 18;1(6076):1561–1563. [PMC free article] [PubMed]

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