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Logo of jroyalcgpracBJGP at RCGPBJGP at PubMed CentralJ R Coll Gen Pract at PubMed CentralRCGP homepage
J R Coll Gen Pract. 1976 August; 26(169): 595–598.
PMCID: PMC2158348

Complications of `Slow-K' therapy


(1) The failure of `Slow-K' tablets to disintegrate prevents rapid release but allows them to be trapped by their bulk in the intestine.

(2) Two cases are reported. In the first the tablet was trapped in a caecal diverticulum and the patient developed an abcess. In the second, abdominal pain developed which subsided when `Slow-K' was stopped. Later `Slow-K' was again started and the patient developed dysphagia.

(3) The possibility of abdominal complications with this treatment should be remembered.

(4) Effervescent KC1 preparations may replace `Slow-K' but KC1 supplementation may be necessary only in cardiac disease.

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Selected References

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  • Dargie HJ, Boddy K, Kennedy AC, King PC, Read PR, Ward DM. Total body potassium in long-term frusemide therapy: is potassium supplementation necessary? Br Med J. 1974 Nov 9;4(5940):316–319. [PMC free article] [PubMed]
  • Edmondson RP, Thomas RD, Hilton PJ, Patrick J, Jones NF. Leucocyte electrolytes in cardiac and non-cardiac patients receiving diuretics. Lancet. 1974 Jan 5;1(7845):12–14. [PubMed]
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  • Wilkinson PR, Issler H, Hesp R, Raftery EB. Total body and serum potassium during prolonged thiazide therapy for essential hypertension. Lancet. 1975 Apr 5;1(7910):759–762. [PubMed]
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  • Modlin JF, Herrmann K, Brandling-Bennett AD, Eddins DL, Hayden GF. Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women. N Engl J Med. 1976 Apr 29;294(18):972–974. [PubMed]

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