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Anesth Prog. 1994; 41(1): 1–5.
PMCID: PMC2148708

Respiratory effects of a balanced anesthetic technique--revisited fifteen years later.


Five hundred and fifty patients underwent general anesthesia with fentanyl, diazepam, and methohexital. Forty-seven (8.5%) developed signs of hypoventilation or airway obstruction. Arterial blood gas analysis revealed mild hypoxemia in three of the 47 cases and mild hypercarbia in six. Airway obstruction was more predictive of abnormal blood gas values than was hypoventilation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Campbell RL, Gregg JM, Levin KJ. Cardiorespiratory effects of a balanced anesthetic technique in outpatient general anesthesia. J Oral Surg. 1976 May;34(5):399–406. [PubMed]
  • Campbell RL, Shamaskin RG, Saunders VW. Analysis of cardiovascular changes and arterial blood gases in patients resistant to methohexital anesthesia. Anesth Prog. 1987 Mar-Apr;34(2):51–57. [PMC free article] [PubMed]
  • Cohen PJ, Alexander SC, Smith TC, Reivich M, Wollman H. Effects of hypoxia and normocarbia on cerebral blood flow and metabolism in conscious man. J Appl Physiol. 1967 Aug;23(2):183–189. [PubMed]
  • Olsen RW, Yang J, King RG, Dilber A, Stauber GB, Ransom RW. Barbiturate and benzodiazepine modulation of GABA receptor binding and function. Life Sci. 1986 Nov 24;39(21):1969–1976. [PubMed]
  • Brogden RN, Goa KL. Flumazenil. A preliminary review of its benzodiazepine antagonist properties, intrinsic activity and therapeutic use. Drugs. 1988 Apr;35(4):448–467. [PubMed]
  • Dundee JW, Halliday NJ, Harper KW, Brogden RN. Midazolam. A review of its pharmacological properties and therapeutic use. Drugs. 1984 Dec;28(6):519–543. [PubMed]
  • Rubin A, Allen GD, Everett GB. Induction of general anesthesia with diazepam or thiopental: a comparison of the cardiorespiratory effects. Anesth Prog. 1978 Mar-Apr;25(2):39–44. [PMC free article] [PubMed]
  • Samuelson PN, Reves JG, Kouchoukos NT, Smith LR, Dole KM. Hemodynamic responses to anesthetic induction with midazolam or diazepam in patients with ischemic heart disease. Anesth Analg. 1981 Nov;60(11):802–809. [PubMed]
  • McGimpsey JG, Kawar P, Gamble JA, Browne ES, Dundee JW. Midazolam in dentistry. Br Dent J. 1983 Jul 23;155(2):47–50. [PubMed]

Articles from Anesthesia Progress are provided here courtesy of American Dental Society of Anesthesiology