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J Bacteriol. Nov 1984; 160(2): 702–705.
PMCID: PMC214793
Two-component suppression of recF143 by recA441 in Escherichia coli K-12.
M R Volkert, L J Margossian, and A J Clark
Sensitivity to UV irradiation conferred by recF143 was partially suppressed by recA441 (also known as tif-1). A temperature-conditional component depended on uvrA function and is thought to involve thermal induction of excision repair enzymes. In a uvrA6 mutant, a temperature-independent component of suppression was seen. This is thought to indicate that recA441 also caused temperature-independent changes in recA activity. Two hypotheses are offered to explain how recA441 produced both thermosensitive and thermoindependent effects.
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