Similar mitochondrial responses to calcium entry and to calcium mobilization by agonists. Cells were coloaded with rhod-2 and Calcium Green esters, examined in perforated patch, and the data analyzed, all as in Fig. Fig.4.4. Each record is representative of 3–5 similar experiments. (A) At the indicated times a single cell was perfused with 100 nM bradykinin (BK) for 5 s. After recovery, a 250-ms depolarization (ΔV) was applied. (B) Cam and Cac responses of another cell to a 5-s perfusion with 50 μM muscarine (musc) and subsequent depolarization.