Search tips
Search criteria 


Logo of jhyg
J Hyg (Lond). 1984 December; 93(3): 455–463.
PMCID: PMC2129463

Experimental infection of castrated lambs with Mycoplasma agalactiae.


The course of experimental infection in groups of 6-month-old castrated lambs with field isolates of Mycoplasma agalactiae from France was followed culturally and serologically for 7 months. Infection with an ovine field isolate following inoculation by different routes and contact exposure was compared with that caused similarly by a caprine field isolate. The prolonged infections produced were symptomless apart from limited arthritis in one animal inoculated with the isolate from sheep and increased lachrymation in another associated with the goat isolate. The ovine isolate was more virulent in that ante- and post-mortem recoveries of the organism were more consistent and the serological responses more pronounced. Serological responses varied between animals and between strain infections, and the results of the film inhibition test were more consistent than those of the complement fixation test. The limitations of both these tests for detecting carrier infections are discussed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Foggie A, Etheridge JR, Erdağ O, Arisoy F. Contagious agalactia of sheep and goats. The serial passage in goats of an attenuated strain of Mycoplasma agalactiae AIK40. Res Vet Sci. 1970 Sep;11(5):477–479. [PubMed]
  • Ruhnke HL, Thawley D, Nelson FC. Bovine mastitis in Ontario due to Mycoplasma agalactiae subsp. bovis. Can J Comp Med. 1976 Apr;40(2):142–148. [PMC free article] [PubMed]
  • Schaeren W, Nicolet J. Anwendung eines Micro-ELISA für die Serologie der infektiösen Agalaktie der Ziegen. Schweiz Arch Tierheilkd. 1982 Apr;124(4):163–177. [PubMed]
  • Shabanov M, Toshkov A, Mikhailova L, Shirova L. Eksperimentalen mastit s Mycoplasma agalactiae u ovtse. Vet Med Nauki. 1973;10(10):81–84. [PubMed]
  • Thorns CJ, Boughton E. Studies on film production and its specific inhibition, with special reference to Mycoplasma bovis (M. agalactiae var. bovis). Zentralbl Veterinarmed B. 1978 Oct;25(8):657–667. [PubMed]
  • Toshkov A, Shirova L, Mikhailova L, Shabanov M. Prouchvaniia v'rkhu infektsioziia i imunizatorniia protses pri mikoplazmozi. V. Eksperimentalna infektsiia s Mycoplasma agalactiae u agneta. Acta Microbiol Virol Immunol (Sofiia) 1975;2:42–47. [PubMed]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press