Table 1
Neuropsychological and neurological data at baseline and at follow‐up
Neuropsychological and neurological data at baseline and at follow‐up| Baseline (0 wk) | FU 1 (26 wk) | FU 2 (52 wk) | FU 3 (156 wk) | FU 4 (157 wk) | FU 5 (163 wk) | FU 6 (180 wk) | |
|---|---|---|---|---|---|---|---|
| Stimulation parameters | |||||||
| Contacts, right/left monopolar | 1‐/1‐2‐ | 1‐/1‐2‐ | 1‐/1‐2 | Off | 3‐/2‐3‐ | 3‐/2‐3‐ | |
| Amplitude (V) right/left | 3.2/2.5 | 3.2/2.5 | 3.2/2.5 | 2.6/2.5 | 2.6/2.5 | ||
| Pulse width (μs) | 60 | 60 | 60 | 60 | 60 | ||
| Frequency (Hz) | 185 | 185 | 185 | 130 | 130 | ||
| UPDRS‐III (off/on) | 56/34 | 21/13 | 21/13 | /14 | 22/ | /18 | |
| H&Y (off/on) | 3/3 | 3/2,5 | 3/2,5 | /2,5 | 3/ | /2 | |
| Medication | |||||||
| Pergolide (mg) | 6–8 | 4 | 3 | 2 | 2 | 2 | 0 |
| LEU | 880 | 750 | 510 | 760 | 760 | 760 | 560 |
| Executive function | |||||||
| Category fluency (T) | 47 | 43 | 44 | 37 | 46 | 33 | 35 |
| COWAT letter fluency (T) | 52 | 51 | 50 | 55 | 56 | 60 | 63 |
| Stroop colour–word (T) | 39 | 33 | 44 | 34 | 28 | 32 | 37 |
| Trailmaking B (T) | 49 | 51 | 60 | 42 | 47 | 44 | 56 |
| PASAT number correct | 47 | 33 | 25 | 29 | 39 | 38 | 38 |
| Memory | |||||||
| AVLT immediate recall (T) | 51 | 37 | 38 | 37 | 33 | 37 | 45 |
| AVLT delayed recall (T) | 46 | 30 | 34 | 31 | 35 | 35 | 39 |
| Decision‐making | |||||||
| IGT disadvantageous choices% | 34 | 56 | 78 | 70 | |||
| Go/no go commission errors% | 48 | 43 | 68 | 77 | |||
| Questionnaires | |||||||
| DEX Questionnaire self/proxy | 11/23 | 10/29 | 6/22 | 15/42 | 11/56 | 9/50 | 10/28 |
| PDQL | 87 | 71 | 70 | 66 | 66 | 70 | |
| MADRS | 8 | 9 | 3 | 7 | 9 | 9 |
AVLT, Auditory Verbal Learning Test; COWAT, Controlled Oral Word Association Test; DEX, Dysexecutive Questionnaire; FU, Follow‐up; H&Y, Hoehn and Yahr scale; IGT, Iowa Gambling Task; LEU, levodopa equivalent unit; MADRS, Montgomery and Asberg Depression Rating Scale; PASAT, Paced Auditory Serial Addition Test; PDQL, Parkinson's Disease Quality of Life; T, normally distributed score with a mean of 50 and SD of 10, corrected for age and education; UPDRS, Unified Parkinson's Disease Rating Scale.
Significant changes in cognitive test scores (compared with baseline) are printed in bold typeface.