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The rays destroy, partially destroy, or injure cells, especially the nucleus. The injured cells may recover, so that further radiation is usually advisable after eight weeks. In throat conditions, overdosage is the great danger, owing to insufficient body-fluid coverings, and to the presence of large air cavities, which prevent the proper diffusion of rays and the striking back of those which penetrate the growth. The use of glucose and the permeating of the growth with metals in minute subdivision in order to cause secondary radiations advised. The best method of all, if practicable, would be to fill the air cavities with fluids, after preliminary tracheotomy. The main advantages of deep therapy are the ease with which wide areas can be radiated and the flexibility of the method. By varying the voltage and the filters with the depth from the surface, one can get diffusion of the rays, because the softer the ray the greater its absorption. This method is extremely safe, even for out-patients. Surgery when possible is always advisable. Diathermy is best, followed within three days by radiation. In doubtful cases partial radiation immediately before operation is advisable, to be completed within ten days after operation. Formation of antibodies is considered to be a vital factor. These are formed as the result of the absorption of the destroyed cells. In all malignant conditions the same dosage is now administered. After-treatment of hospital cases is most important. Artificial sunlight is advised, also sending the patient to an institution or convalescent home.