Monozygotic twins (aged 63 years old), with group‐2A idiopathic juxtafoveolar retinal telangiectasia (JXT), underwent clinical examination, fluorescein angiography (FA) and optical coherence tomography (OCT). Twin 1: Right fundus showed right‐angled venules temporal to the fovea; FA demonstrated retino‐retinal anastomosis and intraretinal leakage. Twin 2: Fundoscopy revealed right‐angled venules in both eyes. OCT demonstrated foveal cysts in all eyes. This is the third set of monozygotic twins with group‐2A JXT that has been reported in the literature, further supporting a genetic predisposition for JXT. The twin who smoked had more severe disease, suggesting that smoking is a risk factor for progression. OCT is useful in the detection and monitoring of these patients.
Group‐2A JXT is characterised by bilateral regions of retinal thickening temporal to the fovea with minimal exudation.1 Gass and Blodi described five stages of group‐2A JXT.1 OCT clearly depicts the involvement of the intraretinal and subretinal spaces in this condition. Intraretinal cysts, lamellar hole, subretinal fibrosis and speckled intraretinal yellow‐red hyper‐reflectivity have been reported.2
We report identical twin sisters with group‐2A JXT.