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|Annotated ORFsa||Orthologous genes||Orthologous adjacent pairsb||Divergent pairse||Convergent pairse||Tandem pairse|
|Stringently conserved pairs (ratio)c||94 (6.30%)||95 (6.45%)||156 (5.70%)|
|Loosely conserved pairs (ratio)d||942 (63.18%)||973 (66.01%)||1667 (60.91%)|
aFor analysis, the annotated ORFs exclude dubious and silent ORFS as well as overlapping genes.
bThe orthologous adjacent pairs of the sensu stricto species are determined based on conservation of the orthologs as well as their adjacency relationship in S. cerevisiae.
cGene pairs with adjacency relationship preserved in all five species for the orthologous pairs.
dGene pairs with adjacency relationship preserved in any three species, or in S. castelli with at least one another yeast species used in this study.
eThe proportions of conservation for different adjacent patterns are similar to those for random sampling composition (p > 0.05, chi-square test).