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Br J Cancer. May 1978; 37(5): 849–857.
PMCID: PMC2009630
Allocation of patients to treatment groups in a controlled clinical study.
S. J. White and L. S. Freedman
In a controlled clinical study ("clinical trial") to compare 2 or more treatments for a disease, an objective method of allocating patients to treatment groups is needed. Various existing methods of allocation are described, including those which take account of patients' pre-treatment characteristics.
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