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Lyn Pilowsky was a pioneer in the use of single photon emission tomography in schizophrenia research, being one of the first psychiatrists to use this method in the world. She was the first to demonstrate that high dose typical antipsychotic treatment conferred no additional benefit in treatment resistant patients, thus reducing unnecessary side effects substantially. She was also the first to uncover the basis of the atypical action (limbic selectivity) of clozapine. Her more recent work concentrated on novel targets for treatment in schizophrenia such as NMDA and sigma-1 receptors. Lyn had a passion for music, and was the lead singer in a bluegrass band for several years. She loved life, taking great pleasure in everything she did. Those who were privileged to work with Lyn will miss her friendship, her academic leadership, her gift for laughter and fun, and her unwavering personal and professional integrity. She was a devoted mother to her daughter, Judith, who survives her.
Professor of psychiatry Institute of Psychiatry, London (b 1961; q Flinders University 1986; MRCPsych, PhD), died from a brain tumour on 16 July 2007.