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Br J Cancer. 1985 February; 51(2): 271–278.
PMCID: PMC1977023

Frequency of benign and malignant breast lesions in 207 consecutive autopsies in Australian women.


A histopathological study was undertaken on breast tissue dissected during the course of 207 consecutive forensic post-mortems on women over the age of 15 years in order to define the frequency and types of lesions found in Australian women. At least 10 blocks were obtained from each breast and a total of 4,738 blocks were examined. A particularly high frequency of atypical hyperplasia (12.6%), carcinoma in situ (13.0%), focal secretory change (24.1%) and perilobular haemangiomas (11.2%) was found. The radial scar, considered by some to be a precursor of infiltrating ductal carcinoma was found in 7.7% of the women.

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Selected References

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  • Black MM, Barclay TH, Cutler SJ, Hankey BF, Asire AJ. Association of atypical characteristics of benign breast lesions with subsequent risk of breast cancer. Cancer. 1972 Feb;29(2):338–343. [PubMed]
  • Brown RW, Meehan C, Martin FI, Bhathal PS. Breast tumors in patients with hyperprolactinemia. Cancer. 1982 Jul 1;50(1):125–129. [PubMed]
  • Fenoglio C, Lattes R. Sclerosing papillary proliferations in the female breast. A benign lesion often mistaken for carcinoma. Cancer. 1974 Mar;33(3):691–700. [PubMed]
  • Fisher ER, Palekar AS, Kotwal N, Lipana N. A nonencapsulated sclerosing lesion of the breast. Am J Clin Pathol. 1979 Mar;71(3):240–246. [PubMed]
  • Foote FW, Stewart FW. Comparative Studies of Cancerous Versus Noncancerous Breasts. Ann Surg. 1945 Jan;121(1):6–53. [PubMed]
  • FRANTZ VK, PICKREN JW, MELCHER GW, AUCHINCLOSS H., Jr Indicence of chronic cystic disease in so-called "normal breasts; a study based on 225 postmortem examinations. Cancer. 1951 Jul;4(4):762–783. [PubMed]
  • Humphrey LJ, Swerdlow M. Histologic changes in clinically normal breasts at postmortem examination. Arch Surg. 1966 Feb;92(2):192–193. [PubMed]
  • Kramer WM, Rush BF., Jr Mammary duct proliferation in the elderly. A histopathologic study. Cancer. 1973 Jan;31(1):130–137. [PubMed]
  • Lee PA, Kelly MR, Wallin JD. Increased prolactin levels during reserpine treatment of hypertensive patients. JAMA. 1976 May 24;235(21):2316–2317. [PubMed]
  • Lesueur GC, Brown RW, Bhathal PS. Incidence of perilobular hemangioma in the female breast. Arch Pathol Lab Med. 1983 Jun;107(6):308–310. [PubMed]
  • RYAN JA, COADY CJ. Intraductal epithelial proliferation in the human breast-a comparative study. Can J Surg. 1962 Jan;5:12–19. [PubMed]
  • Shah HS, Mathur BB. Cystic disease and carcinoma of the breast. A four quadrant study of normal and cancerous breasts. Indian J Pathol Bacteriol. 1967 Apr;10(2):197–203. [PubMed]
  • SLOSS PT, BENNETT WA, CLAGETT OT. Incidence in normal breasts of features associated with chronic cystic mastitis. Am J Pathol. 1957 Nov-Dec;33(6):1181–1191. [PubMed]
  • Wellings SR, Alpers CE. Subgross pathologic features and incidence of radial scars in the breast. Hum Pathol. 1984 May;15(5):475–479. [PubMed]
  • Wellings SR, Jensen HM, Marcum RG. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst. 1975 Aug;55(2):231–273. [PubMed]

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