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Br J Cancer. 1994 May; 69(5): 957–960.
PMCID: PMC1968891

The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.

Abstract

Anticipatory nausea and vomiting (ANV) after repeated cycles of cytotoxic chemotherapy is thought to be a conditioned response to a conditioning stimulus. Good control of acute and delayed emesis may result in a lower incidence of ANV. We have analysed data from 574 chemotherapy patients who received granisetron as their antiemetic treatment during repeat cycle chemotherapy. Per treatment cycle, less than 10% of patients displayed symptoms of anticipatory nausea and 2% or less had symptoms of anticipatory vomiting. It is concluded that the use of granisetron as an antiemetic during the acute phase of chemotherapy may result in a lower incidence of ANV in patients undergoing repeat cycle chemotherapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
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Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK