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J Bacteriol. 1994 September; 176(18): 5587–5600.
PMCID: PMC196760

The superfamily of heme-copper respiratory oxidases.

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  • Alge D, Peschek GA. Identification and characterization of the ctaC (coxB) gene as part of an operon encoding subunits I, II, and III of the cytochrome c oxidase (cytochrome aa3) in the cyanobacterium Synechocystis PCC 6803. Biochem Biophys Res Commun. 1993 Feb 26;191(1):9–17. [PubMed]
  • Anemüller S, Bill E, Schäfer G, Trautwein AX, Teixeira M. EPR studies of cytochrome aa3 from Sulfolobus acidocaldarius. Evidence for a binuclear center in archaebacterial terminal oxidase. Eur J Biochem. 1992 Nov 15;210(1):133–138. [PubMed]
  • Anemüller S, Schäfer G. Cytochrome aa3 from Sulfolobus acidocaldarius. A single-subunit, quinol-oxidizing archaebacterial terminal oxidase. Eur J Biochem. 1990 Jul 31;191(2):297–305. [PubMed]
  • Anraku Y. Bacterial electron transport chains. Annu Rev Biochem. 1988;57:101–132. [PubMed]
  • Babcock GT, Wikström M. Oxygen activation and the conservation of energy in cell respiration. Nature. 1992 Mar 26;356(6367):301–309. [PubMed]
  • Batut J, Daveran-Mingot ML, David M, Jacobs J, Garnerone AM, Kahn D. fixK, a gene homologous with fnr and crp from Escherichia coli, regulates nitrogen fixation genes both positively and negatively in Rhizobium meliloti. EMBO J. 1989 Apr;8(4):1279–1286. [PubMed]
  • Bott M, Bolliger M, Hennecke H. Genetic analysis of the cytochrome c-aa3 branch of the Bradyrhizobium japonicum respiratory chain. Mol Microbiol. 1990 Dec;4(12):2147–2157. [PubMed]
  • Bott M, Preisig O, Hennecke H. Genes for a second terminal oxidase in Bradyrhizobium japonicum. Arch Microbiol. 1992;158(5):335–343. [PubMed]
  • Brown S, Moody AJ, Mitchell R, Rich PR. Binuclear centre structure of terminal protonmotive oxidases. FEBS Lett. 1993 Feb 1;316(3):216–223. [PubMed]
  • Buse G, Hensel S, Fee JA. Evidence for cytochrome oxidase subunit I and a cytochrome c--subunit II fused protein in the cytochrome 'c1aa3' of Thermus thermophilus. How old is cytochrome oxidase? Eur J Biochem. 1989 Apr 15;181(1):261–268. [PubMed]
  • Calhoun MW, Hill JJ, Lemieux LJ, Ingledew WJ, Alben JO, Gennis RB. Site-directed mutants of the cytochrome bo ubiquinol oxidase of Escherichia coli: amino acid substitutions for two histidines that are putative CuB ligands. Biochemistry. 1993 Nov 2;32(43):11524–11529. [PubMed]
  • Calhoun MW, Lemieux LJ, Thomas JW, Hill JJ, Goswitz VC, Alben JO, Gennis RB. Spectroscopic characterization of mutants supports the assignment of histidine-419 as the axial ligand of heme o in the binuclear center of the cytochrome bo ubiquinol oxidase from Escherichia coli. Biochemistry. 1993 Dec 7;32(48):13254–13261. [PubMed]
  • Calhoun MW, Oden KL, Gennis RB, de Mattos MJ, Neijssel OM. Energetic efficiency of Escherichia coli: effects of mutations in components of the aerobic respiratory chain. J Bacteriol. 1993 May;175(10):3020–3025. [PMC free article] [PubMed]
  • Calhoun MW, Thomas JW, Hill JJ, Hosler JP, Shapleigh JP, Tecklenburg MM, Ferguson-Miller S, Babcock GT, Alben JO, Gennis RB. Identity of the axial ligand of the high-spin heme in cytochrome oxidase: spectroscopic characterization of mutants in the bo-type oxidase of Escherichia coli and the aa3-type oxidase of Rhodobacter sphaeroides. Biochemistry. 1993 Oct 12;32(40):10905–10911. [PubMed]
  • Cao J, Hosler J, Shapleigh J, Revzin A, Ferguson-Miller S. Cytochrome aa3 of Rhodobacter sphaeroides as a model for mitochondrial cytochrome c oxidase. The coxII/coxIII operon codes for structural and assembly proteins homologous to those in yeast. J Biol Chem. 1992 Dec 5;267(34):24273–24278. [PubMed]
  • Capaldi RA. Structure and function of cytochrome c oxidase. Annu Rev Biochem. 1990;59:569–596. [PubMed]
  • Castresana J, Lübben M, Saraste M, Higgins DG. Evolution of cytochrome oxidase, an enzyme older than atmospheric oxygen. EMBO J. 1994 Jun 1;13(11):2516–2525. [PubMed]
  • Chan SI, Li PM. Cytochrome c oxidase: understanding nature's design of a proton pump. Biochemistry. 1990 Jan 9;29(1):1–12. [PubMed]
  • Chepuri V, Gennis RB. The use of gene fusions to determine the topology of all of the subunits of the cytochrome o terminal oxidase complex of Escherichia coli. J Biol Chem. 1990 Aug 5;265(22):12978–12986. [PubMed]
  • Chepuri V, Lemieux L, Au DC, Gennis RB. The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases. J Biol Chem. 1990 Jul 5;265(19):11185–11192. [PubMed]
  • Denda K, Fujiwara T, Seki M, Yoshida M, Fukumori Y, Yamanaka T. Molecular cloning of the cytochrome aa3 gene from the archaeon (Archaebacterium) Halobacterium halobium. Biochem Biophys Res Commun. 1991 Nov 27;181(1):316–322. [PubMed]
  • Efiok BJ, Webster DA. A cytochrome that can pump sodium ion. Biochem Biophys Res Commun. 1990 Nov 30;173(1):370–375. [PubMed]
  • Fee JA, Yoshida T, Surerus KK, Mather MW. Cytochrome caa3 from the thermophilic bacterium Thermus thermophilus: a member of the heme-copper oxidase superfamily. J Bioenerg Biomembr. 1993 Apr;25(2):103–114. [PubMed]
  • Fu HA, Iuchi S, Lin EC. The requirement of ArcA and Fnr for peak expression of the cyd operon in Escherichia coli under microaerobic conditions. Mol Gen Genet. 1991 Apr;226(1-2):209–213. [PubMed]
  • Fujiwara T, Fukumori Y, Yamanaka T. Purification and properties of Halobacterium halobium "cytochrome aa3" which lacks CuA and CuB. J Biochem. 1989 Feb;105(2):287–292. [PubMed]
  • Fukaya M, Tayama K, Tamaki T, Ebisuya H, Okumura H, Kawamura Y, Horinouchi S, Beppu T. Characterization of a cytochrome a1 that functions as a ubiquinol oxidase in Acetobacter aceti. J Bacteriol. 1993 Jul;175(14):4307–4314. [PMC free article] [PubMed]
  • Gabel C, Maier RJ. Nucleotide sequence of the coxA gene encoding subunit I of cytochrome aa3 of Bradyrhizobium japonicum. Nucleic Acids Res. 1990 Oct 25;18(20):6143–6143. [PMC free article] [PubMed]
  • Garcia-Horsman JA, Barquera B, Escamilla JE. Two different aa3-type cytochromes can be purified from the bacterium Bacillus cereus. Eur J Biochem. 1991 Aug 1;199(3):761–768. [PubMed]
  • García-Horsman JA, Berry E, Shapleigh JP, Alben JO, Gennis RB. A novel cytochrome c oxidase from Rhodobacter sphaeroides that lacks CuA. Biochemistry. 1994 Mar 15;33(10):3113–3119. [PubMed]
  • Gennis RB. Prokaryotic models for mitochondrial cytochrome c oxidase. Biochem Soc Trans. 1993 Nov;21(4):992–998. [PubMed]
  • Georgiou CD, Webster DA. Purification and partial characterization of the membrane-bound cytochrome o(561,564) from Vitreoscilla. Biochemistry. 1987 Oct 6;26(20):6521–6526. [PubMed]
  • Goldbeck RA, Einarsdóttir O, Dawes TD, O'Connor DB, Surerus KK, Fee JA, Kliger DS. Magnetic circular dichroism study of cytochrome ba3 from Thermus thermophilus: spectral contributions from cytochromes b and a3 and nanosecond spectroscopy of CO photodissociation intermediates. Biochemistry. 1992 Oct 6;31(39):9376–9387. [PubMed]
  • Gray KA, Grooms M, Myllykallio H, Moomaw C, Slaughter C, Daldal F. Rhodobacter capsulatus contains a novel cb-type cytochrome c oxidase without a CuA center. Biochemistry. 1994 Mar 15;33(10):3120–3127. [PubMed]
  • Gunsalus RP. Control of electron flow in Escherichia coli: coordinated transcription of respiratory pathway genes. J Bacteriol. 1992 Nov;174(22):7069–7074. [PMC free article] [PubMed]
  • Haltia T, Saraste M, Wikström M. Subunit III of cytochrome c oxidase is not involved in proton translocation: a site-directed mutagenesis study. EMBO J. 1991 Aug;10(8):2015–2021. [PubMed]
  • Hendler RW, Pardhasaradhi K, Reynafarje B, Ludwig B. Comparison of energy-transducing capabilities of the two- and three-subunit cytochromes aa3 from Paracoccus denitrificans and the 13-subunit beef heart enzyme. Biophys J. 1991 Aug;60(2):415–423. [PubMed]
  • Hill BC. The sequence of electron carriers in the reaction of cytochrome c oxidase with oxygen. J Bioenerg Biomembr. 1993 Apr;25(2):115–120. [PubMed]
  • Hill S, Viollet S, Smith AT, Anthony C. Roles for enteric d-type cytochrome oxidase in N2 fixation and microaerobiosis. J Bacteriol. 1990 Apr;172(4):2071–2078. [PMC free article] [PubMed]
  • Hosler JP, Ferguson-Miller S, Calhoun MW, Thomas JW, Hill J, Lemieux L, Ma J, Georgiou C, Fetter J, Shapleigh J, et al. Insight into the active-site structure and function of cytochrome oxidase by analysis of site-directed mutants of bacterial cytochrome aa3 and cytochrome bo. J Bioenerg Biomembr. 1993 Apr;25(2):121–136. [PubMed]
  • Hosler JP, Fetter J, Tecklenburg MM, Espe M, Lerma C, Ferguson-Miller S. Cytochrome aa3 of Rhodobacter sphaeroides as a model for mitochondrial cytochrome c oxidase. Purification, kinetics, proton pumping, and spectral analysis. J Biol Chem. 1992 Dec 5;267(34):24264–24272. [PubMed]
  • Hosler JP, Shapleigh JP, Tecklenburg MJ, Thomas JW, Kim Y, Espe M, Fetter J, Babcock GT, Alben JO, Gennis RB, et al. A loop between transmembrane helices IX and X of subunit I of cytochrome c oxidase caps the heme a-heme a3-CuB center. Biochemistry. 1994 Feb 8;33(5):1194–1201. [PubMed]
  • Ishizuka M, Machida K, Shimada S, Mogi A, Tsuchiya T, Ohmori T, Souma Y, Gonda M, Sone N. Nucleotide sequence of the gene coding for four subunits of cytochrome c oxidase from the thermophilic bacterium PS3. J Biochem. 1990 Nov;108(5):866–873. [PubMed]
  • Jurtshuk P, Jr, Mueller TJ, Wong TY. Isolation and purification of the cytochrome oxidase of Azotobacter vinelandii. Biochim Biophys Acta. 1981 Sep 14;637(2):374–382. [PubMed]
  • Kai M, Yano T, Tamegai H, Fukumori Y, Yamanaka T. Thiobacillus ferrooxidans cytochrome c oxidase: purification, and molecular and enzymatic features. J Biochem. 1992 Dec;112(6):816–821. [PubMed]
  • Keefe RG, Maier RJ. Purification and characterization of an O2-utilizing cytochrome-c oxidase complex from Bradyrhizobium japonicum bacteroid membranes. Biochim Biophys Acta. 1993 Nov 2;1183(1):91–104. [PubMed]
  • Kelly M, Lappalainen P, Talbo G, Haltia T, van der Oost J, Saraste M. Two cysteines, two histidines, and one methionine are ligands of a binuclear purple copper center. J Biol Chem. 1993 Aug 5;268(22):16781–16787. [PubMed]
  • Kelly MJ, Poole RK, Yates MG, Kennedy C. Cloning and mutagenesis of genes encoding the cytochrome bd terminal oxidase complex in Azotobacter vinelandii: mutants deficient in the cytochrome d complex are unable to fix nitrogen in air. J Bacteriol. 1990 Oct;172(10):6010–6019. [PMC free article] [PubMed]
  • Kranz RG, Gennis RB. Immunological investigation of the distribution of cytochromes related to the two terminal oxidases of Escherichia coli in other gram-negative bacteria. J Bacteriol. 1985 Feb;161(2):709–713. [PMC free article] [PubMed]
  • Lappalainen P, Aasa R, Malmström BG, Saraste M. Soluble CuA-binding domain from the Paracoccus cytochrome c oxidase. J Biol Chem. 1993 Dec 15;268(35):26416–26421. [PubMed]
  • Lauraeus M, Haltia T, Saraste M, Wikström M. Bacillus subtilis expresses two kinds of haem-A-containing terminal oxidases. Eur J Biochem. 1991 May 8;197(3):699–705. [PubMed]
  • Lauraeus M, Wikström M. The terminal quinol oxidases of Bacillus subtilis have different energy conservation properties. J Biol Chem. 1993 May 25;268(15):11470–11473. [PubMed]
  • Lemieux LJ, Calhoun MW, Thomas JW, Ingledew WJ, Gennis RB. Determination of the ligands of the low spin heme of the cytochrome o ubiquinol oxidase complex using site-directed mutagenesis. J Biol Chem. 1992 Jan 25;267(3):2105–2113. [PubMed]
  • Lemma E, Schägger H, Kröger A. The menaquinol oxidase of Bacillus subtilis W23. Arch Microbiol. 1993;159(6):574–578. [PubMed]
  • Lübben M, Kolmerer B, Saraste M. An archaebacterial terminal oxidase combines core structures of two mitochondrial respiratory complexes. EMBO J. 1992 Mar;11(3):805–812. [PubMed]
  • Ludwig B. Terminal oxidases in Paracoccus denitrificans. Biochim Biophys Acta. 1992 Jul 17;1101(2):195–197. [PubMed]
  • Malmström BG, Aasa R. The nature of the CuA center in cytochrome c oxidase. FEBS Lett. 1993 Jun 28;325(1-2):49–52. [PubMed]
  • Mather MW, Springer P, Hensel S, Buse G, Fee JA. Cytochrome oxidase genes from Thermus thermophilus. Nucleotide sequence of the fused gene and analysis of the deduced primary structures for subunits I and III of cytochrome caa3. J Biol Chem. 1993 Mar 15;268(8):5395–5408. [PubMed]
  • Matsushita K, Ebisuya H, Adachi O. Homology in the structure and the prosthetic groups between two different terminal ubiquinol oxidases, cytochrome a1 and cytochrome o, of Acetobacter aceti. J Biol Chem. 1992 Dec 5;267(34):24748–24753. [PubMed]
  • Matsushita K, Ebisuya H, Ameyama M, Adachi O. Change of the terminal oxidase from cytochrome a1 in shaking cultures to cytochrome o in static cultures of Acetobacter aceti. J Bacteriol. 1992 Jan;174(1):122–129. [PMC free article] [PubMed]
  • Matsushita K, Shinagawa E, Adachi O, Ameyama M. o-Type cytochrome oxidase in the membrane of aerobically grown Pseudomonas aeruginosa. FEBS Lett. 1982 Mar 22;139(2):255–258. [PubMed]
  • Matsushita K, Shinagawa E, Adachi O, Ameyama M. Cytochrome a1 of acetobacter aceti is a cytochrome ba functioning as ubiquinol oxidase. Proc Natl Acad Sci U S A. 1990 Dec;87(24):9863–9867. [PubMed]
  • Matsushita K, Takahashi K, Takahashi M, Ameyama M, Adachi O. Methanol and ethanol oxidase respiratory chains of the methylotrophic acetic acid bacterium, Acetobacter methanolicus. J Biochem. 1992 Jun;111(6):739–747. [PubMed]
  • Minagawa J, Mogi T, Gennis RB, Anraku Y. Identification of heme and copper ligands in subunit I of the cytochrome bo complex in Escherichia coli. J Biol Chem. 1992 Jan 25;267(3):2096–2104. [PubMed]
  • Minghetti KC, Goswitz VC, Gabriel NE, Hill JJ, Barassi CA, Georgiou CD, Chan SI, Gennis RB. Modified, large-scale purification of the cytochrome o complex (bo-type oxidase) of Escherichia coli yields a two heme/one copper terminal oxidase with high specific activity. Biochemistry. 1992 Aug 4;31(30):6917–6924. [PubMed]
  • Miyoshi-Akiyama T, Hayashi M, Unemoto T. Purification and properties of cytochrome bo-type ubiquinol oxidase from a marine bacterium Vibrio alginolyticus. Biochim Biophys Acta. 1993 Mar 1;1141(2-3):283–287. [PubMed]
  • Nobrega MP, Nobrega FG, Tzagoloff A. COX10 codes for a protein homologous to the ORF1 product of Paracoccus denitrificans and is required for the synthesis of yeast cytochrome oxidase. J Biol Chem. 1990 Aug 25;265(24):14220–14226. [PubMed]
  • Poole RK. Bacterial cytochrome oxidases. A structurally and functionally diverse group of electron-transfer proteins. Biochim Biophys Acta. 1983 Sep 15;726(3):205–243. [PubMed]
  • Preisig O, Anthamatten D, Hennecke H. Genes for a microaerobically induced oxidase complex in Bradyrhizobium japonicum are essential for a nitrogen-fixing endosymbiosis. Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3309–3313. [PubMed]
  • Puustinen A, Finel M, Haltia T, Gennis RB, Wikström M. Properties of the two terminal oxidases of Escherichia coli. Biochemistry. 1991 Apr 23;30(16):3936–3942. [PubMed]
  • Puustinen A, Finel M, Virkki M, Wikström M. Cytochrome o (bo) is a proton pump in Paracoccus denitrificans and Escherichia coli. FEBS Lett. 1989 Jun 5;249(2):163–167. [PubMed]
  • Puustinen A, Morgan JE, Verkhovsky M, Thomas JW, Gennis RB, Wikström M. The low-spin heme site of cytochrome o from Escherichia coli is promiscuous with respect to heme type. Biochemistry. 1992 Oct 27;31(42):10363–10369. [PubMed]
  • Quirk PG, Hicks DB, Krulwich TA. Cloning of the cta operon from alkaliphilic Bacillus firmus OF4 and characterization of the pH-regulated cytochrome caa3 oxidase it encodes. J Biol Chem. 1993 Jan 5;268(1):678–685. [PubMed]
  • Qureshi MH, Yumoto I, Fujiwara T, Fukumori Y, Yamanaka T. A novel aco-type cytochrome-c oxidase from a facultative alkalophilic Bacillus: purification, and some molecular and enzymatic features. J Biochem. 1990 Mar;107(3):480–485. [PubMed]
  • Raitio M, Jalli T, Saraste M. Isolation and analysis of the genes for cytochrome c oxidase in Paracoccus denitrificans. EMBO J. 1987 Sep;6(9):2825–2833. [PubMed]
  • Raitio M, Pispa JM, Metso T, Saraste M. Are there isoenzymes of cytochrome c oxidase in Paracoccus denitrificans? FEBS Lett. 1990 Feb 26;261(2):431–435. [PubMed]
  • Rice CW, Hempfling WP. Oxygen-limited continuous culture and respiratory energy conservation in Escherichia coli. J Bacteriol. 1978 Apr;134(1):115–124. [PMC free article] [PubMed]
  • Saiki K, Mogi T, Ogura K, Anraku Y. In vitro heme O synthesis by the cyoE gene product from Escherichia coli. J Biol Chem. 1993 Dec 15;268(35):26041–26044. [PubMed]
  • Santana M, Kunst F, Hullo MF, Rapoport G, Danchin A, Glaser P. Molecular cloning, sequencing, and physiological characterization of the qox operon from Bacillus subtilis encoding the aa3-600 quinol oxidase. J Biol Chem. 1992 May 25;267(15):10225–10231. [PubMed]
  • Saraste M. Structural features of cytochrome oxidase. Q Rev Biophys. 1990 Nov;23(4):331–366. [PubMed]
  • Saraste M, Castresana J. Cytochrome oxidase evolved by tinkering with denitrification enzymes. FEBS Lett. 1994 Mar 14;341(1):1–4. [PubMed]
  • Saraste M, Metso T, Nakari T, Jalli T, Lauraeus M, Van der Oost J. The Bacillus subtilis cytochrome-c oxidase. Variations on a conserved protein theme. Eur J Biochem. 1991 Jan 30;195(2):517–525. [PubMed]
  • Schrattenholz AS, Nawroth T, Dose K. Isolation and partial characterization of a cytochrome-o complex from chromatophores of the photosynthetic bacterium Rhodospirillum rubrum FR1. Eur J Biochem. 1989 May 15;181(3):689–694. [PubMed]
  • Scott RA, Zumft WG, Coyle CL, Dooley DM. Pseudomonas stutzeri N2O reductase contains CuA-type sites. Proc Natl Acad Sci U S A. 1989 Jun;86(11):4082–4086. [PubMed]
  • Shapleigh JP, Gennis RB. Cloning, sequencing and deletion from the chromosome of the gene encoding subunit I of the aa3-type cytochrome c oxidase of Rhodobacter sphaeroides. Mol Microbiol. 1992 Mar;6(5):635–642. [PubMed]
  • Shapleigh JP, Hosler JP, Tecklenburg MM, Kim Y, Babcock GT, Gennis RB, Ferguson-Miller S. Definition of the catalytic site of cytochrome c oxidase: specific ligands of heme a and the heme a3-CuB center. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4786–4790. [PubMed]
  • Shoji K, Yamazaki T, Nagano T, Fukumori Y, Yamanaka T. Thiobacillus novellus cytochrome c oxidase contains one heme alpha molecule and one copper atom per catalytic unit. J Biochem. 1992 Jan;111(1):46–53. [PubMed]
  • Solioz M, Carafoli E, Ludwig B. The cytochrome c oxidase of Paracoccus denitrificans pumps protons in a reconstituted system. J Biol Chem. 1982 Feb 25;257(4):1579–1582. [PubMed]
  • Sone N, Fujiwara Y. Effects of aeration during growth of Bacillus stearothermophilus on proton pumping activity and change of terminal oxidases. J Biochem. 1991 Dec;110(6):1016–1021. [PubMed]
  • Sone N, Fujiwara Y. Haem O2 can replace haem A in the active site of cytochrome c oxidase from thermophilic bacterium PS3. FEBS Lett. 1991 Aug 19;288(1-2):154–158. [PubMed]
  • Sone N, Kutoh E, Sato K. A cytochrome o-type oxidase of the thermophilic bacterium PS3 grown under air-limited conditions. J Biochem. 1990 Apr;107(4):597–602. [PubMed]
  • Sone N, Ogura T, Noguchi S, Kitagawa T. Proton pumping activity and visible absorption and resonance Raman spectra of a cao-type cytochrome c oxidase isolated from the thermophilic bacterium Bacillus PS3. Biochemistry. 1994 Feb 1;33(4):849–855. [PubMed]
  • Sone N, Yanagita Y. High vectorial proton stoichiometry by cytochrome c oxidase from the thermophilic bacterium PS3 reconstituted in liposomes. J Biol Chem. 1984 Feb 10;259(3):1405–1408. [PubMed]
  • Sone N, Yokoi F, Fu T, Ohta S, Metso T, Raitio M, Saraste M. Nucleotide sequence of the gene coding for cytochrome oxidase subunit I from the thermophilic bacterium PS3. J Biochem. 1988 Apr;103(4):606–610. [PubMed]
  • Surpin MA, Moshiri F, Murphy AM, Maier RJ. Genetic evidence for a fourth terminal oxidase in Bradyrhizobium japonicum. Gene. 1994 May 27;143(1):73–77. [PubMed]
  • Svensson B, Lübben M, Hederstedt L. Bacillus subtilis CtaA and CtaB function in haem A biosynthesis. Mol Microbiol. 1993 Oct;10(1):193–201. [PubMed]
  • Tano H, Ishizuka M, Sone N. The cytochrome C oxidase genes in blue-green algae and characteristics of the deduced protein sequence for subunit II of the thermophilic cyanobacterium Synechococcus vulcanus. Biochem Biophys Res Commun. 1991 Nov 27;181(1):437–442. [PubMed]
  • Thomas JW, Lemieux LJ, Alben JO, Gennis RB. Site-directed mutagenesis of highly conserved residues in helix VIII of subunit I of the cytochrome bo ubiquinol oxidase from Escherichia coli: an amphipathic transmembrane helix that may be important in conveying protons to the binuclear center. Biochemistry. 1993 Oct 19;32(41):11173–11180. [PubMed]
  • Thomas JW, Puustinen A, Alben JO, Gennis RB, Wikström M. Substitution of asparagine for aspartate-135 in subunit I of the cytochrome bo ubiquinol oxidase of Escherichia coli eliminates proton-pumping activity. Biochemistry. 1993 Oct 12;32(40):10923–10928. [PubMed]
  • Tzagoloff A, Capitanio N, Nobrega MP, Gatti D. Cytochrome oxidase assembly in yeast requires the product of COX11, a homolog of the P. denitrificans protein encoded by ORF3. EMBO J. 1990 Sep;9(9):2759–2764. [PubMed]
  • Uno T, Mogi T, Tsubaki M, Nishimura Y, Anraku Y. Resonance Raman and Fourier transform infrared studies on the subunit I histidine mutants of the cytochrome bo complex in Escherichia coli. Molecular structure of redox metal centers. J Biol Chem. 1994 Apr 22;269(16):11912–11920. [PubMed]
  • van der Oost J, Haltia T, Raitio M, Saraste M. Genes coding for cytochrome c oxidase in Paracoccus denitrificans. J Bioenerg Biomembr. 1991 Apr;23(2):257–267. [PubMed]
  • van der Oost J, Musacchio A, Pauptit RA, Ceska TA, Wierenga RK, Saraste M. Crystallization and preliminary X-ray analysis of the periplasmic fragment of CyoA-a subunit of the Escherichia coli cytochrome o complex. J Mol Biol. 1993 Feb 5;229(3):794–796. [PubMed]
  • van der Oost J, Lappalainen P, Musacchio A, Warne A, Lemieux L, Rumbley J, Gennis RB, Aasa R, Pascher T, Malmström BG, et al. Restoration of a lost metal-binding site: construction of two different copper sites into a subunit of the E. coli cytochrome o quinol oxidase complex. EMBO J. 1992 Sep;11(9):3209–3217. [PubMed]
  • van der Oost J, von Wachenfeld C, Hederstedt L, Saraste M. Bacillus subtilis cytochrome oxidase mutants: biochemical analysis and genetic evidence for two aa3-type oxidases. Mol Microbiol. 1991 Aug;5(8):2063–2072. [PubMed]
  • von Wachenfeldt C, de Vries S, van der Oost J. The CuAsite of the caa3-type oxidase of Bacillus subtilis is a mixed-valence binuclear copper centre. FEBS Lett. 1994 Feb 28;340(1-2):109–113. [PubMed]
  • von Wachenfeldt C, Hederstedt L. Molecular biology of Bacillus subtilis cytochromes. FEMS Microbiol Lett. 1992 Dec 15;100(1-3):91–100. [PubMed]
  • Wikström M. Identification of the electron transfers in cytochrome oxidase that are coupled to proton-pumping. Nature. 1989 Apr 27;338(6218):776–778. [PubMed]
  • Woese CR. Bacterial evolution. Microbiol Rev. 1987 Jun;51(2):221–271. [PMC free article] [PubMed]
  • Yamanaka T, Kamita Y, Fukumori Y. Molecular and enzymatic properties of "cytochrome aa3"-type terminal oxidase derived from Nitrobacter agilis. J Biochem. 1981 Jan;89(1):265–273. [PubMed]
  • Yang T. Tetramethyl-p-phenylenediamine oxidase of Pseudomonas aeruginosa. Eur J Biochem. 1982 Jan;121(2):335–341. [PubMed]
  • Yun CH, Beci R, Crofts AR, Kaplan S, Gennis RB. Cloning and DNA sequencing of the fbc operon encoding the cytochrome bc1 complex from Rhodobacter sphaeroides. Characterization of fbc deletion mutants and complementation by a site-specific mutational variant. Eur J Biochem. 1990 Dec 12;194(2):399–411. [PubMed]
  • Zamudio I, Kornblatt J, Nicholls P, Li Y, Cygler M. Preliminary studies on the crystallization of beef heart cytochrome c oxidase by vapor diffusion. Biochem Biophys Res Commun. 1990 Jun 29;169(3):1105–1110. [PubMed]
  • Zimmermann BH, Nitsche CI, Fee JA, Rusnak F, Münck E. Properties of a copper-containing cytochrome ba3: a second terminal oxidase from the extreme thermophile Thermus thermophilus. Proc Natl Acad Sci U S A. 1988 Aug;85(16):5779–5783. [PubMed]
  • Zumft WG. The biological role of nitric oxide in bacteria. Arch Microbiol. 1993;160(4):253–264. [PubMed]
  • Zumft WG, Braun C, Cuypers H. Nitric oxide reductase from Pseudomonas stutzeri. Primary structure and gene organization of a novel bacterial cytochrome bc complex. Eur J Biochem. 1994 Jan 15;219(1-2):481–490. [PubMed]

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