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Logo of jroyalcgpracBJGP at RCGPBJGP at PubMed CentralJ R Coll Gen Pract at PubMed CentralRCGP homepage
J R Coll Gen Pract. 1986 November; 36(292): 510–511.
PMCID: PMC1960735

Variation in peak expiratory flow in children with asthma


Twice daily peak expiratory flow measurements were obtained at home from 65 asthmatic children and 34 non-asthmatic controls, and a measure of the daily variation in peak expiratory flow was calculated for each child (mean daily variation). Children aged less than 7.5 years appeared unable to provide reproducable peak expiratory flows, but above that age the mean of the mean daily variations was significantly higher for the asthmatics than the controls. This was true even on days when the asthmatics exhibited no wheeze or took no medication. The significance of the findings is discussed, and it is suggested that calculation of the mean daily variation might assist in the assessment of children presenting with atypical respiratory symptoms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Prior JG, Cochrane GM. Home-monitoring of peak expiratory flow rate using mini-Wright peak flow meter in diagnosis of asthma. J R Soc Med. 1980 Oct;73(10):731–733. [PubMed]
  • Hetzel MR, Clark TJ. Comparison of normal and asthmatic circadian rhythms in peak expiratory flow rate. Thorax. 1980 Oct;35(10):732–738. [PMC free article] [PubMed]
  • Muers MF. Diurnal variation in asthma. Arch Dis Child. 1984 Sep;59(9):898–901. [PMC free article] [PubMed]
  • Clark TJ. The Philip Ellman lecture. The circadian rhythm of asthma. Br J Dis Chest. 1985 Apr;79(2):115–124. [PubMed]
  • Speight N. The diagnosis and management of asthma in childhood. Practitioner. 1986 Jun;230(1416):549–552. [PubMed]
  • Toop LJ, Howie JG, Paxton FM. Night cough and general practice research. J R Coll Gen Pract. 1986 Feb;36(283):74–77. [PMC free article] [PubMed]

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