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A survey of 70 consecutive adults having surgery for intractable epilepsy in Gothenburg, Sweden, shows that the outcome at two years predicts that at 10 years, with 91% of those in remission at the former time remaining so.
Of the 65 survivors (two having died of causes related to epilepsy), 38 were free of seizures at a mean follow-up of 12.4 (range 8.6-16.2) years; a further eight had a greater than 75% reduction in the frequency of fits, and nine had a 50-75% reduction. Nine patients had a <50% reduction, and one had worsened.
Results were better in those who had had temporal lobe resection than in those who had had extratemporal: 65% (33 of 51) and 36% (5 of 14) of patients respectively were free of seizures. Use of anticonvulsant medication had reduced considerably, and 11 of the 65 survivors had stopped such treatment. There was no indication that patients had more cognitive or psychiatric morbidity than would be expected from a cohort who had experienced epilepsy for more than half their lives before being referred for surgery.