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Antimicrob Agents Chemother. Sep 1993; 37(9): 2033–2036.
PMCID: PMC188118
Activity of a nitrofurazone matrix urinary catheter against catheter-associated uropathogens.
J R Johnson, T Berggren, and A J Conway
Department of Medicine, University of Minnesota, Minneapolis 55455.
Nitrofurazone-coated urinary catheter segments inhibited 51 (75%) of 70 urinary bacterial isolates from patients with indwelling catheters. Inhibition zones correlated significantly with the nitrofurazone MIC (r2 = 0.79, P = 0.0001). All strains except the Pseudomonas spp. were inhibited by < or = 64 micrograms of nitrofurazone per ml. MICs of nitrofurazone and nitrofurantoin correlated significantly (r2 = 0.93, P = 0.0001).
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