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Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1960 February; 53(2): 71–80.
PMCID: PMC1871194

Biochemical Aspects of Ketosis

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • BEATTY CH, WEST ES. The effect of substances related to the tricarboxylic acid cycle upon ketosis. J Biol Chem. 1951 Jun;190(2):603–610. [PubMed]
  • COLE BT, ENGEL FL, FREDERICKS J. Sodium fluoroacetate diabetes: correlations between glycemia, ketonemia and tissue citrate levels. Endocrinology. 1955 Jun;56(6):675–683. [PubMed]
  • Davies HW, Haldane JB, Kennaway EL. Experiments on the regulation of the blood's alkalinity: I. J Physiol. 1920 Aug 19;54(1-2):32–45. [PubMed]
  • Edson NL. Ketogenesis-antiketogenesis: The influence of ammonium chloride on ketone-body formation in liver. Biochem J. 1935 Sep;29(9):2082–2094. [PubMed]
  • ENGEL FL. Some unexplained metabolic actions of pituitary hormones with a unifying hypothesis concerning their significance. Yale J Biol Med. 1957 Dec;30(3):201–223. [PMC free article] [PubMed]
  • ENGEL FL, ENGEL MG. The ketogenic activity of corticotropin, a presumed extra-adrenal action. Endocrinology. 1958 Feb;62(2):150–158. [PubMed]
  • ENGEL MG, ENGEL FL. Influence of cortisone on the ketogenic response to oxycel corticotropin. Endocrinology. 1958 Jan;62(1):75–77. [PubMed]
  • FASELLA P, TURANO C, BAGLIONI C, SILIPRANDI N. Action of citrate and oxalacetate on dietary and diabetic ketosis. Lancet. 1958 May 24;1(7030):1097–1097. [PubMed]
  • GESSERT RA, SHAW JC, CHUNG AC. Studies on ketosis in dairy cattle. XVII. The value of hydrocortisone therapy. J Am Vet Med Assoc. 1955 Sep;127(942):215–218. [PubMed]
  • HAGER SE, GREGERMAN RI, KNOX WE. p-Hydroxyphenylpyruvate oxidase of liver. J Biol Chem. 1957 Apr;225(2):935–947. [PubMed]
  • HIRD FJ, SYMONS RH. The metabolism of glucose and butyrate by the omasum of the sheep. Biochim Biophys Acta. 1959 Oct;35:422–434. [PubMed]
  • Jowett M, Quastel JH. Studies in fat metabolism: The formation and breakdown of acetoacetic acid in animal tissues. Biochem J. 1935 Sep;29(9):2181–2191. [PubMed]
  • KALNITSKY G, TAPLEY DF. A sensitive method for estimation of oxaloacetate. Biochem J. 1958 Sep;70(1):28–34. [PubMed]
  • KNOX WE, EDWARDS SW. Homogentisate oxidase of liver. J Biol Chem. 1955 Oct;216(2):479–487. [PubMed]
  • Krebs HA, Eggleston LV. Metabolism of acetoacetate in animal tissues. 2. Biochem J. 1948;42(2):294–305. [PubMed]
  • LINK RP, NEWTON DI, HUBER WG. The use of prednisolone in bovine ketosis. J Am Vet Med Assoc. 1957 Feb 1;130(3):137–140. [PubMed]
  • LYNEN F, HENNING U, BUBLITZ C, SORBO B, KROPLIN-RUEFF L. Der chemische Mechanismus der Acetessigsäurebildung in der Leber. Biochem Z. 1958;330(4):269–295. [PubMed]
  • Mackay EM, Sherrill JW, Barnes RH. THE ANTIKETOGENIC ACTIVITY OF SUCCINIC ACID. J Clin Invest. 1939 May;18(3):301–305. [PMC free article] [PubMed]
  • MAHLER HR. Role of coenzyme A in fatty acid metabolism. Fed Proc. 1953 Sep;12(3):694–702. [PubMed]
  • Maplesden DC. Propylene Glycol In The Treatment Of Ketosis. Can J Comp Med Vet Sci. 1954 Aug;18(8):287–293. [PMC free article] [PubMed]
  • PASSMORE R, JOHNSON RE. The modification of post-exercise ketosis (the Courtice-Douglas effect) by environmental temperature and water balance. Q J Exp Physiol Cogn Med Sci. 1958 Oct;43(4):352–361. [PubMed]
  • PENNINGTON RJ. The metabolism of short-chain fatty acids in the sheep. I. Fatty acid utilization and ketone body production by rumen epithelium and other tissues. Biochem J. 1952 May;51(2):251–258. [PubMed]
  • BERTHET J, RALL TW, SUTHERLAND EW. The relationship of epinephrine and glucagon to liver phosphorylase. IV. Effect of epinephrine and glucagon on the reactivation of phosphorylase in liver homogenates. J Biol Chem. 1957 Jan;224(1):463–475. [PubMed]
  • RECKNAGEL RO, POTTER VR. Mechanism of the ketogenic effect of ammonium chloride. J Biol Chem. 1951 Jul;191(1):263–275. [PubMed]
  • SARGENT F, 2nd, JOHNSON RE, ROBBINS E, SAWYER L. The effects of environment and other factors on nutritional ketosis. Q J Exp Physiol Cogn Med Sci. 1958 Oct;43(4):345–351. [PubMed]
  • SCHEPARTZ B. Inhibition and activation of the oxidation of homogentisic acid. J Biol Chem. 1953 Nov;205(1):185–192. [PubMed]
  • SCHULTZ LH. Treatment of ketosis in dairy cattle with sodium propionate. Cornell Vet. 1952 Jan;42(1):148–155. [PubMed]
  • SHAW WV, TAPLEY DF. Oxaloacetate in the livers of alloxan-diabetic rats. Biochim Biophys Acta. 1958 Nov;30(2):426–427. [PubMed]
  • STERN JR, COON MJ, DEL CAMPILLO A. Enzymes of fatty acid metabolism. III. Breakdown and synthesis of beta-keto fatty acids. J Biol Chem. 1956 Jul;221(1):1–14. [PubMed]
  • SUTHERLAND EW, CORI CF. Effect of hyperglycemic-glycogenolytic factor and epinephrine on liver phosphorylase. J Biol Chem. 1951 Feb;188(2):531–543. [PubMed]
  • SUTHERLAND EW, WOSILAIT WD. The relationship of epinephrine and glucagon to liver phosphorylase. I. Liver phosphorylase; preparation and properties. J Biol Chem. 1956 Jan;218(1):459–468. [PubMed]
  • TERNER C. The formation of acetoacetate in homogenates of the mammary gland. Biochem J. 1958 Nov;70(3):402–409. [PubMed]
  • WEINHOUSE S, MILLINGTON RH. A study of acetoacetate "turnover" in rat liver slices in vitro. J Biol Chem. 1951 Nov;193(1):1–10. [PubMed]

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