PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
 
Proc R Soc Med. 1961 May; 54(5): 403–405.
PMCID: PMC1869569

The Inhibition of Acetylcholinesterase by Organophosphorus Compounds and its Reversal [Abridged]

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (544K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • ALDRIDGE WN, DAVISON AN. The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. II. Diethyl p-nitrophenyl thionphosphate (E605) and analogues. Biochem J. 1952 Dec;52(4):663–671. [PubMed]
  • ASKEW BM. Oximes and atropine in sarin poisoning. Br J Pharmacol Chemother. 1957 Sep;12(3):340–343. [PubMed]
  • BERRY WK, DAVIES DR, GREEN AL. Oximes of alpha omega-diquaternary alkane salts as antidotes to organophosphate anticholinesterases. Br J Pharmacol Chemother. 1959 Jun;14(2):186–191. [PubMed]
  • DAVIES DR, GREEN AL. The kinetics of reactivation, by oximes, of cholinesterase inhibited by organophosphorus compounds. Biochem J. 1956 Aug;63(4):529–535. [PubMed]
  • ERDMANN WD. [Clinical experiences with the antidote pyridine-2-aldoxime methiodide (PAM) in E 605 poisoning. Selected cases]. Dtsch Med Wochenschr. 1960 Jun 3;85:1014–1016. [PubMed]
  • HOBBIGER F. Chemical reactivation of phosphorylated human and bovine true cholinesterases. Br J Pharmacol Chemother. 1956 Sep;11(3):295–303. [PubMed]
  • HOBBIGER F, PITMAN M, SADLER PW. Reactivation of phosphorylated acetocholinesterases by pyridinium aldoximes and related compounds. Biochem J. 1960 May;75:363–372. [PubMed]
  • HOBBIGER F, SADLER PW. Protection against lethal organophosphate poisoning by quaternary pyridine aldoximes. Br J Pharmacol Chemother. 1959 Jun;14(2):192–201. [PubMed]
  • HOLMES R. Discussion on poisoning with anticholinesterases. Proc R Soc Med. 1953 Oct;46(10):799–800. [PMC free article] [PubMed]
  • KARLOG O, NIMB M, POULSEN E. Parathion (bladan) forgiftning behandlet med 2-PAM (pyridyl-(2)-aldoxim-N-metyliodid). Ugeskr Laeger. 1958 Feb 6;120(6):177–183. [PubMed]
  • KOELLE GB. Histochemical demonstration of reactivation acetylcholinesterase in vivo. Science. 1957 Jun 14;125(3259):1195–1196. [PubMed]
  • NAMBA T, HIRAKI K. PAM (pyridine-2-aldoxime methiodide) therapy for alkyl-phosphate poisoning. J Am Med Assoc. 1958 Apr 12;166(15):1834–1839. [PubMed]
  • RUTLAND JP. The effect of some oximes in sarin poisoning. Br J Pharmacol Chemother. 1958 Dec;13(4):399–403. [PubMed]
  • WILSON IB. Designing of a new drug with antidotal properties against the nerve gas sarin. Biochim Biophys Acta. 1958 Jan;27(1):196–199. [PubMed]

Articles from Proceedings of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press