Search tips
Search criteria 


Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1976 January; 69(1): 49–51.
PMCID: PMC1864105

Comparative aspects of tumours of the central nervous system in the dog.


A wide variety of tumours of the brain occur in the dog, most commonly in the Boxer breed. Tumours may arise from the subependymal plate which may influence the parts of the brain destroyed and hence the pattern of clinical signs. Because of the small capacity of the dog's skull, vital neurological structures are quickly destroyed and the time course of these events is much shorter than in man. The high incidence of tumours in the Boxer would suggest that this breed might afford a useful model for clinical treatment using, for instance, cytotoxic agents.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (478K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Blakemore WF, Jolly RD. The subependymal plate and associated ependyma in the dog. An ultrastructural study. J Neurocytol. 1972 Jul;1(1):69–84. [PubMed]
  • Fischer K. Subependymale Zellproliferationen und Tumordisposition brachycephaler Hunderassen. Acta Neuropathol. 1967 May 5;8(3):242–254. [PubMed]
  • Lincoln SD, Gorham JR, Davis WC, Ott RL. Studies of old dog encephalitis. II. Electron microscopic and immunohistologic findings. Vet Pathol. 1973;10(2):124–129. [PubMed]
  • Lincoln SD, Gorham JR, Ott RL, Hegreberg GA. Etiologic studies of old dog encephalitis. I. Demonstration of canine distemper viral antigen in the brain in two cases. Vet Pathol. 1971;8(1):1–8. [PubMed]
  • Palmer AC, Malinowski W, Barnett KC. Clinical signs including papilloedema associated with brain tumours in twenty-one dogs. J Small Anim Pract. 1974 Jun;15(6):359–386. [PubMed]
  • Stavrou D, Kaiser E, Dahme E. Zur Orthologie und Pathologie der subependymalen Glia. Karyometrische Untersuchungen bei brachycephalen Hunden. Berl Munch Tierarztl Wochenschr. 1970 May 1;83(9):164–168. [PubMed]
  • WHITE RJ, MACCARTY CS. Cranial nerve function following total cerebral hemispherectomy in the monkey (Macaca rhesus). Proc Staff Meet Mayo Clin. 1959 Jan 7;34(1):22–29. [PubMed]

Articles from Proceedings of the Royal Society of Medicine are provided here courtesy of Royal Society of Medicine Press