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Logo of procrsmedFormerly medchtJournal of the Royal Society of MedicineProceedings of the Royal Society of Medicine
Proc R Soc Med. 1976; 69(Suppl 2): 88–89.
PMCID: PMC1864044

Gemfibrozil treatment: a comparison with clofibrate.


Gemfibrozil was found to be an effective hypotriglyceridaemic agent in types IV, IIb and V hyperlipoproteinaemia. When given at a dose level of 800 mg/day its activity was nearly of the same order of magnitude as 1.5 g/day of clofibrate.

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Selected References

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  • Cooper J, Geizerova H, Oliver MF. Letter: Clofibrate and gallstones. Lancet. 1975 May 10;1(7915):1083–1083. [PubMed]
  • Hess R, Stäubli W, Riess W. Nature of the hepatomegalic effect produced by ethyl-chlorophenoxy-isobutyrate in the rat. Nature. 1965 Nov 27;208(5013):856–858. [PubMed]
  • Pertsemlidis D, Panveliwalla D, Ahrens EH., Jr Effects of clofibrate and of an estrogen-progestin combination on fasting biliary lipids and cholic acid kinetics in man. Gastroenterology. 1974 Apr;66(4):565–573. [PubMed]
  • Stone MC, Thorp JM, Mills GL, Dick TB. Comparison of membrane filtration and nephelometry with analytical ultracentrifugation, for the quantitative analysis of low density lipoprotein fractions. Clin Chim Acta. 1970 Dec;30(3):809–828. [PubMed]

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