1001 A cure for most people with chronic hepatitis B infection — entecavir, a distinct advance on lamivudine.
1021 Don't be too surprised if thalidomide appears on the treatment list of a myeloma patient — it prolongs survival if given at the start of treatment, and works well in the elderly (Lancet page 825), but has a lot of side-effects.
1130 Patients over 70 who are taking antidepressants have a 68% chance of getting depressed again if they stop, reduced to 37% if they carry on. Continued psychotherapy makes no difference.
1157 A good review of acute confusional states (delirium) in the elderly. They can resolve completely with treatment of the cause, or mark a steep decline in a dementing process.
1231 An important pragmatic study from the STAR*D series shows that a third of patients who don't respond to one serotonin reuptake inhibitor (SRI) antidepressant will respond to a different one, or by changing to venlafaxine or bupropion.
1243 Another study from the series looks at adding another agent to the SRI citalopram — and again a third of patients benefited, this time from the addition of buspirone or bupropion.
1343 An old-fashioned egg-based vaccine has now been proved to provide antibodies to H5N1 influenza, should it ever become pandemic. Let's hope there are enough eggs about.