Search tips
Search criteria 


Logo of aacPermissionsJournals.ASM.orgJournalAAC ArticleJournal InfoAuthorsReviewers
Antimicrob Agents Chemother. 1981 September; 20(3): 410–414.
PMCID: PMC181711

Metronidazole Metabolism in Cultures of Entamoeba histolytica and Trichomonas vaginalis


Acetamide forms from metronidazole in cultures of either Entamoeba histolytica or Trichomonas vaginalis as it does in cultures of bacteria which are susceptible to this drug. Under aerobic conditions, the formation of acetamide is more rapid in a strain of T. vaginalis which is more susceptible to metronidazole. Thus, it appears that the formation of acetamide may be associated with the microbiocidal action of metronidazole.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (663K), or click on a page image below to browse page by page.

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)